Inhibition of SARS Pseudovirus Cell Entry by Lactoferrin Binding to Heparan Sulfate ProteoglycansResearch Article Published on 2011-08-222022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] ACE2 addition against SARS-CoV aggregation Analysis angiotensin-converting enzyme 2 binding binding site Cell cell entry cells Defense disease disrupt dose-dependent manner experiment functional Host host cell host cells Host immune response Infection inhibit inhibited inhibition inhibitory Interaction Invasion investigated involved lactoferrin neutrophil NK cell Pathogenesis prevented previous study protective role Proteoglycan pseudovirus pseudovirus infection receptor reported respiratory SARS-CoV severe shown Spike protein suggested sulfate Treatment [DOI] 10.1371/journal.pone.0023710 PMC 바로가기 [Article Type] Research Article
On the Treatment of Airline Travelers in Mathematical ModelsResearch Article Published on 2011-07-252022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] Airline assist assumption change component Critical facilitated Human Infected Infectious disease mathematical mathematical model Model pathogen public health significantly Spread Travel Treatment [DOI] 10.1371/journal.pone.0022151 PMC 바로가기 [Article Type] Research Article
Action Mechanisms of Lithium Chloride on Cell Infection by Transmissible Gastroenteritis CoronavirusResearch Article Published on 2011-05-062022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] Action added Analysis Annexin anti-apoptotic Apoptosis assay bronchitis caspase-3 Cell Cell culture cell lines concerning coronavirus Coronaviruses detected different DNA viruses dose dose-dependent manner effective epidemic diarrhea expression flow cytometry found Genes herpes simplex virus IBV immunofluorescence in vitro indicated Infection infectious inhibit inhibited inhibitory effect initial investigated late stage LiCl lithium Lithium chloride (LiCl mechanism MTT not affected nuclei plaque Post-infection Real-time PCR reported RNA virus RT-PCR staining TGEV Transcription transmissible gastroenteritis virus Treatment vaccinia virus virus [DOI] 10.1371/journal.pone.0018669 PMC 바로가기 [Article Type] Research Article
Human rhinovirus infection in young African children with acute wheezingResearch Article Published on 2011-03-152022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, [키워드] African age analysed Analysis caused Characteristics children circulating clinical disease Culture deaths detect detected determine enrolled Fisher group hospital Hospitalized HRV Human In-hospital increasingly Infection information intensive care métapneumovirus Mild moderate monoclonal antibody morbidity MOST nasal swab occurred other respiratory virus PCR-based assays presenting presenting symptom respiratory virus Result reverse transcription PCR rhinovirus South therapy to screen Treatment Trigger viral infection was performed was used wheezing [DOI] 10.1186/1471-2334-11-65 PMC 바로가기 [Article Type] Research Article
Patient considerations in the management of multiple sclerosis: development and clinical utility of oral agentsReview Published on 2011-02-272024-09-04 Journal: Molecular pharmacology [Category] 대상포진, [키워드] adherence decisions multiple sclerosis Treatment [DOI] 10.2147/PPA.S10506 PMC 바로가기 [Article Type] Review
PLP2 of Mouse Hepatitis Virus A59 (MHV-A59) Targets TBK1 to Negatively Regulate Cellular Type I Interferon Signaling PathwayResearch Article Published on 2011-02-182022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] Activation acute respiratory syndrome assays catalytic domain cells cellular complex conserved coronavirus cytoplasm deubiquitinase domain dose-dependent manner DUB ENCODE Evidence experiment finding identification IFN IFN signaling IFN signaling pathway IFN transcription IFN-β in vitro inactivated inactive Infection inhibit inhibited innate immune system IRF3 MHV-A59 mouse mouse hepatitis virus nonstructural protein 3 Nsp3 nuclear translocation overexpression Papain-like protease phosphorylate PLP2 Prevent principal Proteins receptor reduced Regulatory Replication reporter shown Spread supported target TBK1 TNF TRAF3 Treatment Type type I interferon upstream [DOI] 10.1371/journal.pone.0017192 PMC 바로가기 [Article Type] Research Article
Abatacept in the treatment of polyarticular JIA: development, clinical utility, and place in therapyReview Published on 2011-01-262024-09-04 Journal: Drug Design, Development and Therapy [Category] 대상포진, [키워드] abatacept juvenile idiopathic arthritis Treatment [DOI] 10.2147/DDDT.S16489 PMC 바로가기 [Article Type] Review
Distinct Patterns of IFITM-Mediated Restriction of Filoviruses, SARS Coronavirus, and Influenza A VirusResearch Article Published on 2011-01-062022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] Acidic Author bypasse bypassed cathepsin L Cell cellular cellular tropism circumvent compared Control cytoplasm described did not reduce Ebola Ebola virus Endocytic pathway ENhance example Express expression Factors Filovirus glycoprotein highly pathogenic IAV IFITM IFITM1 IFITM3 indicate Infection infectious influenza A virus inhibit inhibited innate immune system interfere late stage less limit lysosomal modulate murine observation pathogenic viruses pattern plasma membrane Protein Proteins pseudovirions receptor Replication restrict restriction restriction factor SARS Coronavirus SARS-CoV transmembrane transmembrane protein Treatment viral replication virion virus viruses [DOI] 10.1371/journal.ppat.1001258 PMC 바로가기 [Article Type] Research Article
Canine InfluenzaArticle Published on 2010-09-012023-05-31 Journal: The Veterinary Clinics of North America. Small Animal Practice [Category] 조류인플루엔자, [키워드] canine Diagnosis Epidemiology Influenza prevention Treatment [DOI] 10.1016/j.cvsm.2010.07.005 PMC 바로가기 [Article Type] Article
Oseltamivir in human avian influenza infectionArticle Published on 2010-04-012023-05-31 Journal: Journal of Antimicrobial Chemotherapy [Category] 조류인플루엔자, [키워드] clinical H5N1 pre-clinical Prophylaxis Treatment [DOI] 10.1093/jac/dkq013 PMC 바로가기 [Article Type] Article