Oseltamivir in seasonal influenza: cumulative experience in low- and high-risk patientsArticle Published on 2010-04-012023-06-23 Journal: Journal of Antimicrobial Chemotherapy [Category] 신종인플루엔자, [키워드] Efficacy Prophylaxis Safety Treatment [DOI] 10.1093/jac/dkq012 PMC 바로가기 [Article Type] Article
Autoimmune Hepatitis: Single-center Experience of Clinical Presentation, Response to Treatment and Prognosis in Saudi ArabiaOriginal Article Published on 2010-04-012023-08-30 Journal: Saudi journal of gastroenterology : official journ [Category] E형 간염, [키워드] Autoimmune hepatitis clinical presentation Laboratory features Saudi Arabia Treatment [DOI] 10.4103/1319-3767.61235 PMC 바로가기 [Article Type] Original Article
Exacerbated Innate Host Response to SARS-CoV in Aged Non-Human PrimatesResearch Article Published on 2010-02-052022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] acute lung injury acute respiratory distress acute respiratory syndrome advanced age age analyses Analysis anti-inflammatory action ARDS Author cause Comprehensive contributed coronavirus correlated develop different differential expression diminishe disease displaying exacerbated expression Gene genomic H5N1 host response IFN-β IL-8 in viral increase in individual individuals Infection Inflammation influenza A Innate Intervention life-threatening Lungs macaque macaques Microarray modulation molecular mRNA level NF-κB outcome pandemic pathogen Pathogenesis pathology Pathways Patient primate pro-inflammatory gene expression Protective provide reduce reduced Replication response reveal SARS-CoV SARS-CoV infection severe severe pathology severity shown significantly significantly more syndrome Treatment type I Type I IFN type I interferon viral infection viral replication viral respiratory virus infection virus replication without affecting [DOI] 10.1371/journal.ppat.1000756 PMC 바로가기 [Article Type] Research Article
Avian coronavirus infectious bronchitis virus susceptibility to botanical oleoresins and essential oils in vitro and in vivoArticle Published on 2010-01-212022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] addition Administering Botanical extracts Clinical sign Compound coronavirus CPE, cytopathic effects Dilution disease effective EID50, 50% embryo infectious dose ELISA, enzyme linked immunosorbent assay essential oils examined expected greater HMA, hexamethylene amiloride Host IBV IBV, infectious bronchitis virus in vitro in vivo Infection Infectious Bronchitis Virus investigated knowledge Laboratory lesion Massachusett MHV, mouse hepatitis virus Natural ingredients Oleoresins PBS, phosphate buffered saline protection reduced RFLP, restriction fragment length polymorphism RT-PCR, Reverse transcriptase-polymerase chain reaction SARS-CoV, Severe Acute Respiratory Syndrome virus serotype severity SPF, specific pathogen free susceptibility TCID50, 50% tissue culture infectious dose Transmission Treatment Vero E6 cell Viral RNA virucidal virus Virus challenge virus inactivation virus titer viruses was determined [DOI] 10.1016/j.virusres.2010.01.006 PMC 바로가기 [Article Type] Article
Cleavage of the SARS Coronavirus Spike Glycoprotein by Airway Proteases Enhances Virus Entry into Human Bronchial Epithelial Cells In VitroResearch Article Published on 2009-11-172022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] 16HBE ACE2 ACE2 binding Activation acute respiratory syndrome against SARS-CoV airway Amino acid Analysis arginine residue bronchial bronchial epithelial cell cell entry Chromatography cleavage cleaved coronavirus demonstrated dependent on different Efficacy Efficiency exhibited expand expressing expression Extracellular finding full-length glycoprotein host cell HPLC Human implication in vitro investigated lack liquid mechanism molecular basis mutant not affect performance potential therapeutic agent protease Proteases Protein R667 R797 Receptor binding regulate Respiratory system S-protein SARS-CoV SARS-CoV infection Sequencing shown spike susceptibility susceptible Treatment trimer trypsin viral entry viral envelope virus virus entry [DOI] 10.1371/journal.pone.0007870 PMC 바로가기 [Article Type] Research Article
Inducible Bronchus-Associated Lymphoid Tissue Elicited by a Protein Cage Nanoparticle Enhances Protection in Mice against Diverse Respiratory VirusesResearch Article Published on 2009-09-232022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] accelerate accelerated antibody production Antigen appear Asymptomatic B cell CAGE cause CD4+ T cell clearance described destruction develop different disparate dose ENhance finding functional Host immune response immune response immune responses Immune-mediated Immunity independent Infection Inflammation influenza viruses inherent less limit lung lung damage Lymphoid tissue mechanisms morbidity nanoparticle novel virus pathogen Primary infection primary viral infection protection protective immune response Protein pulmonary viral recruitment Replication respiratory respiratory virus Safe SARS-coronavirus significant decrease significantly significantly increased specificity survival Treatment Vaccination strategies viral antigens viral clearance virus [DOI] 10.1371/journal.pone.0007142 PMC 바로가기 [Article Type] Research Article
Novel Biomarkers for the Diagnosis of Urinary Tract Infection—A Systematic Review요로 감염 진단을 위한 새로운 바이오마커 - 체계적인 검토Review Published on 2009-08-052022-08-08 Journal: Biomarker Insights [Category] Biochemistry, [키워드] age asymptomatic bacteriuria Atypical bacteriuria Biomarker Clinical management conducted criteria database diabetics diagnose Diagnosis Diagnostic accuracy Diagnostic Criteria evaluated extreme immunocompromised individuals IMPROVE individual Infection interleukin interleukin 6 kidney transplant recipients methodology morbidity novel novel biomarkers paucity of data pediatric Population Prevalence procalcitonin procalcitonin level pyelonephritis Reporting review searched serum severity shown spinal cord Spinal cord injury STARD subgroup tract Treatment Urinalysis urinary urinary tract infection urinary tract infections urine culture UTI PMC 바로가기 [Article Type] Review
Brucella endocarditis with splenic abscess: a report of the first case diagnosed in KoreaCase Reports Published on 2009-02-282023-06-02 Journal: Yonsei medical journal [Category] 조류인플루엔자, [키워드] Brucella abortus brucellosis Endocarditis splenic abscess Treatment [DOI] 10.3349/ymj.2009.50.1.142 PMC 바로가기 [Article Type] Case Reports
A Case of Multidrug-Resistant Salmonella enterica Serovar Typhi Treated with a Bench to Bedside Approach다제내성 살모넬라 엔테리카 세로바르 타이피 치료 사례: 벤치에서 침대까지 접근법journal-article Published on 2009-01-012024-08-02 Journal: Yonsei Medical Journal [Category] 살모넬라증, [키워드] multi-drug resistance Salmonella enterica serovar Typhi Treatment [DOI] 10.3349/ymj.2009.50.1.147 [Article Type] journal-article
SARS-Coronavirus Replication/Transcription Complexes Are Membrane-Protected and Need a Host Factor for Activity In VitroResearch Article Published on 2008-05-022022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] activity acute respiratory syndrome addition Author cause centrifugation characteristic complex complexes connection Critical cytoplasm cytoplasmic Degradation dependent on develop digestion dissect eight enzyme Enzymes Factor fraction functional genomic RNA Host host cell membranes host cells in vitro in vitro activity Infected infected cell life-threatening membrane membrane structure membrane structures membranes non-structural protein NSP Nsps polyproteins precursor produced protease PROTECT protein synthesis released remained replicate Replication required RNA RNA synthesis robust RTC SARS-coronavirus SARS-CoV SARS-CoV-infected cells Structure subgenomic mRNA subgenomic mRNA synthesis subunit susceptible Transcription Treatment viral genome replication Viral RNA viral RNA synthesis virus-induced membrane structure virus-induced membrane structures [DOI] 10.1371/journal.ppat.1000054 PMC 바로가기 [Article Type] Research Article