Efficacy of genogroup 1 based porcine epidemic diarrhea live vaccine against genogroup 2 field strain in JapanResearch Published on 2018-02-022022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] Administered Antibody titer caused Clinical sign conditions control group diarrhea Efficacy epidemic diarrhea evaluated exhibited immune response Immunity Infectious disease Japan lactogenic Lactogenic immunity mortality rate negative control Newborn PEDV Porcine epidemic diarrhea Porcine epidemic diarrhea virus pregnant prevalent reduced Result serum significantly supplementary material survival rate Symptom the vaccine vaccination Vaccine virus Virus neutralization watery [DOI] 10.1186/s12985-018-0940-8 PMC 바로가기 [Article Type] Research
Evaluation of an accelerated hydrogen peroxide disinfectant to inactivate porcine epidemic diarrhea virus in swine feces on aluminum surfaces under freezing conditionsResearch Article Published on 2017-12-012022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] accelerated Accelerated hydrogen peroxide addition aluminum applied collected Concentration condition conditions Contact Contamination control group country determine Dilution Disinfection Efficacy epidemic diarrhea evaluated expected fecal glycol hydrogen peroxide inactivated infectious dose Infectivity inoculated negative and positive negative control nucleocapsid PEDV polymerase chain positive positive control Quantitative Randomly rectal swab representing Result reverse transcription RT-qPCR Seven Spread supplementary material Swab swine temperature Treatment treatment group virus was determined were used [DOI] 10.1186/s12917-017-1300-4 PMC 바로가기 [Article Type] Research Article
Case–control study of pathogens involved in piglet diarrheaResearch Article Published on 2016-01-112022-10-27 Journal: BMC Research Notes [Category] Coronavirus, MERS, [키워드] Affect affected anthelminthic antibiotic Bacterial Campylobacter Case–control study Clostridium perfringen Co-infection control group control groups coronavirus Coronaviruses determine Diagnosis diarrhea disease Eimeria epidemic diarrhea Escherichia coli evaluated fecal samples gastroenteritis host immune system Interaction Interpretation investigated involved Laboratory management Measures medication Occurrence pathogen pathogenic agent Piglets positive Prophylactic proportion protozoan parasites Result Salmonella statistically significant difference virus [DOI] 10.1186/s13104-015-1751-2 PMC 바로가기 [Article Type] Research Article
Daily consumption of ready-to-use peanut-based therapeutic food increased fat free mass, improved anemic status but has no impact on the zinc status of people living with HIV/AIDS: a randomized controlled trial바로 사용할 수 있는 땅콩 기반 치료 식품을 매일 섭취하면 무지방 질량이 증가하고 빈혈 상태가 개선되지만 HIV/AIDS 감염자의 아연 상태에는 영향을 미치지 않습니다. 무작위 대조 시험Research Article Published on 2016-01-042022-08-09 Journal: BMC Public Health [Category] 임상, [키워드] adjusted Admission affected AIDS Anemia anemic anemic status ART atomic absorption spectrometry Bio-Impedance Analysis Body body composition body fat body weight both groups clinical trial comparable Concentration conducted Control control group Controlled Controlled clinical trial CRP Daily daily recommended intake deficiency discharge energy fat Fat free mass fat-free mass food group hemoglobin HIV/AIDS Hospitalized Improving Individual dietary Infection iron Malnutrition measure muscle mass on admission patients percentage body fat plasma plasma zinc concentration PLWH positive Randomized controlled trial Randomly ready-to-use therapeutic food receive Recommended Dietary Allowances Registered remained Result Senegal severe malnutrition significantly standard hospital diet status sub-Saharan Africa the patient therapeutic Therapeutic food Treatment was determined was measured were measured Zinc zinc deficiency α1-AGP [DOI] 10.1186/s12889-015-2639-8 PMC 바로가기 [Article Type] Research Article
Epigenome-Guided Analysis of the Transcriptome of Plaque Macrophages during Atherosclerosis Regression Reveals Activation of the Wnt Signaling Pathway죽상경화증 퇴행 동안 플라크 대식세포의 전사체에 대한 후성유전체 분석은 Wnt 신호 전달 경로의 활성화를 보여줍니다Research Article Published on 2014-12-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activated Affect Analysis annotations approach arterial plaque macrophage arteries Atherosclerosis binding site canonical Cell cell motility cell type chromatin circulating condition control group demonstrated detect differentially expressed drug treatments eight element enrichment epigenomic eQTL Evidence expression foam cell functional Gene Expression humans identify in vitro in vivo increase Inflammation inflammatory disease inflammatory state innate immune system less Lipoproteins lowering Macrophage Macrophage response macrophage responses macrophages mice Migration molecular mouse model network overlap plaque plaque macrophage plaque macrophage response plaque macrophage responses plaque macrophages plaque regression plaques plasma lipoprotein plasma lipoproteins power promoter promoters reducing regressing plaque regressing plaques Regression Regression model regression models regulatory region response reversed risk significantly SNPs statins statistically Stimulation Systems biology TCF/LEF therapeutic target transcription factor transcription factors transcriptional change Transcriptome upregulated upregulated gene upregulated genes upstream validation study while Wnt Wnt signaling Wnt signaling pathway β-catenin [DOI] 10.1371/journal.pgen.1004828 PMC 바로가기 [Article Type] Research Article
High-dose dietary zinc oxide mitigates infection with transmissible gastroenteritis virus in pigletsResearch Article Published on 2014-03-282022-10-28 Journal: BMC veterinary research [Category] Coronavirus, MERS, [키워드] added addition Apoptosis cause chloride Concentration control group coronavirus cytokine decrease detectable diarrhea Diseases down-regulation Electrophysiology epithelial evaluate the effect fecal Fecal consistency Final gastroenteritis group groups humoral immune response IFN in vivo incidence Infection interferon intestinal intestinal tract mechanism mitigate Morphometry mucosal immune OAS oral physiological PROTECT protective effect receiving reduce response Result secretion serum antibody response severity shown SLC30A1 SLC30A5 SLC39A4 stimulate TGEV three group transmissible gastroenteritis virus villus virus virus infection was performed Zinc zinc oxide Zinc transporters [DOI] 10.1186/1746-6148-10-75 PMC 바로가기 [Article Type] Research Article
Detection of human coronaviruses in simultaneously collected stool samples and nasopharyngeal swabs from hospitalized children with acute gastroenteritisResearch Published on 2013-02-052022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] 95% CI 95% confidence interval age Asymptomatic children collected Control control group coronavirus detected detected in stool detection Elective surgery etiology gastroenteritis Gastrointestinal infection healthy control healthy controls Hospitalized Human Human coronavirus human coronavirus nasopharyngeal Nasopharyngeal swab NP swab NP swabs Occurrence Odds ratio Patient Prevalence Probability real time recalled respiratory infection respiratory symptom respiratory symptoms Result RT-PCR significantly higher Stool Stool sample stools Swab tested Viral gastroenteritis virus [DOI] 10.1186/1743-422X-10-46 PMC 바로가기 [Article Type] Research
Comparative Genomics of Korean Infectious Bronchitis Viruses (IBVs) and an Animal Model to Evaluate Pathogenicity of IBVs to the Reproductive OrgansArticle Published on 2012-10-302022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Amino acid analysis Analysis animal animal model applied backbone Comparative Comparative genomics control group different Efficacy Gene Genome genomic Genomics Genotype IBV identity inactivated Infection Infectious Bronchitis Virus inhibited Korean lesions Massachusett maturation Model nucleotide ovarian ovarian follicle formation oviduct pathogenicity recombinant virus Recombination reproductive organ strain Vaccine virus was performed [DOI] 10.3390/v4112670 PMC 바로가기 [Article Type] Article
Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS VirusResearch Article Published on 2012-04-202022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] acute respiratory syndrome antibody C57BL/6 candidate vaccine caution challenge change changes in China component control group country dosage eosinophil evaluated exhibited ferret Histopathology Human hypersensitivity immunopathology inactivated indicated Infection infiltration Influenza initiated led to Live virus lung Lung disease mice NHP occurred Occurrence pathologic PBS pulmonary responses Result S protein SARS Coronavirus SARS-CoV SARS-CoV vaccine serum antibody Serum neutralizing antibody severe Significant reduction significantly spread to Th2-type the vaccine Vaccine Vaccine development virus VLP [DOI] 10.1371/journal.pone.0035421 PMC 바로가기 [Article Type] Research Article
Pathogenesis and Tissue Distribution of Avian Infectious Bronchitis Virus Isolate IRFIBV32 (793/B Serotype) in Experimentally Infected Broiler ChickensResearch Article Published on 2012-04-012022-10-29 Journal: The Scientific World Journal [Category] Coronavirus, [키워드] age Antibody titer Broiler bronchitis chicken Clinical sign collected control group demonstrated Depression detected digestive distribution exhibited experimental group indicated Infected Infectious Bronchitis Virus inoculated intranasally isolate kidney lung mild respiratory number of infected oviduct Randomly RNA serotype tissue Trachea two group various tissue viral disease Viral RNA virus virus detection was reduced [DOI] 10.1100/2012/402537 PMC 바로가기 [Article Type] Research Article