dockECR: Open consensus docking and ranking protocol for virtual screening of small moleculesdockECR: 소분자의 가상 스크리닝을 위한 개방형 합의 도킹 및 순위 지정 프로토콜Article Published on 2021-12-012022-09-11 Journal: Journal of molecular graphics & modelling [Category] SARS, 치료기술, 치료제, [키워드] accelerate addition applied approaches AutoDock AutoDock vina average Candidates co-crystallized complement Consensus crystal structure docking eight emerging disease evaluated Exponential consensus ranking Frame information Interaction library molecular molecular docking molecular dynamics Molecular dynamics simulation molecular dynamics simulations molecules Open source predicted protease Protein Protein target protocol ranking residue RMSD SARS-CoV-2 SARS-CoV-2 main protease SARS-CoV-2 virus small molecule targets the SARS-CoV-2 virus Treatment Virtual screening was used were used [DOI] 10.1016/j.jmgm.2021.108023 PMC 바로가기 [Article Type] Article
The effect of opening window position on aerosol transmission in an enclosed bus under windless environmentARTICLES Published on 2021-12-012022-10-28 Journal: Physics of Fluids [Category] COVID-19, [키워드] accelerate addition analyzed Characteristics Concentration Contact droplet effective examined expand high risk highest Infection potential risk PROTECT reducing Transmission transmission of SARS-CoV-2 Variation virus virus spread [DOI] 10.1063/5.0073171 PMC 바로가기 [Article Type] ARTICLES
Advances in the computational landscape for repurposed drugs against COVID-19COVID-19에 대한 용도가있는 약물에 대한 계산 환경의 발전Review Published on 2021-12-012022-08-31 Journal: Drug discovery today [Category] 신약개발, 치료제, [키워드] accelerate advance analyses caused clinical trials Compound Computational drug Computational drug repurposing COVID-19 COVID-19 pandemic de novo death distress docking Docking and molecular dynamics drug drugs Efficacy effort highlight Host in silico Interaction limitation list machine learning mechanism methodology molecular molecular docking molecular dynamics network analysis pathway predicted produced recent Repository Repurposed drug Research SARS-CoV-2 Structure-guided machine learning Viral protein Viral proteins Virus–host interaction network analysis. [DOI] 10.1016/j.drudis.2021.07.026 PMC 바로가기 [Article Type] Review
Modelling long-term COVID-19 impacts on the U.S. workforce of 2029Research Article Published on 2021-12-012022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] accelerate acquisition activities anticipated changes in cognitive COVID COVID-19 COVID-19 pandemic Critical decrease employment engage Health illness Impact impacts increases in Injury knowledge labor less physical Result stability Statistics subject while [DOI] 10.1371/journal.pone.0260797 PMC 바로가기 [Article Type] Research Article
Identification of Novel Malaria Transmission-Blocking Vaccine Candidates새로운 말라리아 전파 차단 백신 후보 식별Cellular and Infection Microbiology Published on 2021-11-302022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] Coronavirus, MERS, SARS, 말라리아, [키워드] accelerate addition approach candidate children clinical development Control COVID-19 develop Efficacy effort Human humans identification immuno-profiling include malaria measure morbidity and mortality novel Plasmodium Plasmodium falciparum reached reactogenicity reduce reduced required Research reverse vaccinology Significant significantly sub-Saharan Africa the WHO Transmission Transmission-blocking vaccine (TBV) Vaccine Vaccines wheat germ cell-free system (WGCFS) widespread [DOI] 10.3389/fcimb.2021.805482 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Pediatric COVID-19 Therapeutics Seizing the Right Research and Development Opportunities to Accelerate Access for Children소아 코비드 19 치료제 어린이의 접근을 가속화 할 수있는 올바른 연구 및 개발 기회를 포착Commentary Published on 2021-11-262022-09-10 Journal: The Pediatric Infectious Disease Journal [Category] SARS, 신약개발, [키워드] accelerate Accelerator access Adults benefit children COVID-19 development lower risk opportunity outcome pediatric pediatrics Perspective Prognosis Research research and development right SARS-CoV-2 therapeutic therapeutic interventions therapeutic trials Therapeutics Trial understanding [DOI] 10.1097/INF.0000000000003331 PMC 바로가기 [Article Type] Commentary
Assessing Values and Preferences Toward SARS-CoV-2 Self-testing Among the General Population and Their Representatives, Health Care Personnel, and Decision-Makers: Protocol for a Multicountry Mixed Methods StudyProtocol Published on 2021-11-262022-10-29 Journal: JMIR Research Protocols [Category] COVID-19, [키워드] accelerate Accessibility Analysis analyzed Assessing Care coded Community Complete conducted counseling country COVID-19 cross-sectional survey Decision-making determine diagnose diagnostic dissemination effective enrolled Enrollment event General population Health Health care worker health care workers health system Identifier identify India Indonesia infected individual inquiry Kenya Laboratory lack Local Mixed methods multisite National Nigeria objective participant patient groups Population preference Prevent protocol provide quarantine raise report response Result Safe SARS-CoV-2 SARS-CoV-2 testing Screening self-testing South specificity Spread Surveillance Testing transcribed Transmission value widespread [DOI] 10.2196/33088 PMC 바로가기 [Article Type] Protocol
The Impact of the COVID-19 Pandemic on Oncology Care and Clinical TrialsReview Published on 2021-11-252022-10-31 Journal: Cancers [Category] COVID-19, [키워드] accelerate affected approval approved Cancer cancer patient Cancer patients Cancer screening Care caused clinical Clinical practice clinical trial clinical trials conducted coronavirus coronavirus disease COVID-19 COVID-19 situation diagnose drugs healthcare healthcare service Impact initial management oncology pandemic Patient recruitment Regulatory SARS-CoV-2 seeking simple subsequent Symptoms Therapies Treatment treatments for COVID-19 Trial undergo vaccination Vaccine virus [DOI] 10.3390/cancers13235924 PMC 바로가기 [Article Type] Review
Broadening symptom criteria improves early case identification in SARS-CoV-2 contacts증상 기준을 넓히면 SARS-CoV-2 접촉자의 조기 사례 식별이 향상됩니다.Original Research Article Published on 2021-11-252022-09-11 Journal: The European Respiratory Journal [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] accelerate Accuracy added average canonical Case isolation Cohort cohorts Community Contact Contact tracing criteria criterion datasets diagnostic value greater headache identify IMPROVE improvement Improvements include Inclusion independent individual Infection information likelihood ratio muscle aches PCR-confirmed PCR-positive Prevent provided quantified recruited reduce reduction in remained Result SARS-CoV-2 SARS-CoV-2 transmission sensitivity sore throat specificity speed Symptom Taste test dataset training dataset uninfected [DOI] 10.1183/13993003.02308-2021 PMC 바로가기 [Article Type] Original Research Article
Risk factors associated with prolonged viral clearance in patients with a refractory course of COVID-19: a retrospective studyVirology Published on 2021-11-232022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] 95% CI accelerate Analysis Aspartate aminotransferase association AST Characteristics Clinical characteristics cohort of patient Course COVID-19 enrolled Factor Fever hazard Huoshenshan Hospital illness onset independent risk factor indicated material median Multivariate analysis Patient performed ranged refractory Reinfection Result Retrospective study Risk factors SARS-CoV-2 SARS-CoV-2 IgG Serum level study cohort suggested Treatment viral clearance [DOI] 10.7717/peerj.12535 PMC 바로가기 [Article Type] Virology