Alterations of lipid metabolism provide serologic biomarkers for the detection of asymptomatic versus symptomatic COVID-19 patients지질 대사의 변화는 무증상 COVID-19 환자와 증상이 있는 COVID-19 환자의 검출을 위한 혈청학적 바이오마커를 제공합니다Article Published on 2021-07-092022-09-10 Journal: Scientific Reports [Category] SARS, 바이오마커, 임상, 치료기술, [키워드] alteration Asymptomatic asymptomatic individual Asymptomatic individuals attenuate Biochemistry Biomarker Biomarkers Care convalescent COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 samples demonstrated Early detection early treatment elevated exhibited Health Health care help heterogeneous Illness severity individual involved lipid metabolism Lipidomics majority moderate moderate to severe negative controls positive Predictive markers pro-inflammatory response pro-inflammatory responses Protein reduced Regulation SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2-infected patient SARS-CoV-2-infected patients selective serum serum sphingolipid serum sphingolipids severe disease severity of COVID-19 sphingolipid sphingolipids sphingosine Spread symptomatic symptomatic COVID-19 Symptoms the disease Viral viral infection viral infections western blotting [DOI] 10.1038/s41598-021-93857-7 PMC 바로가기 [Article Type] Article
Nationwide Seroprevalence of SARS-CoV-2 in Saudi Arabia사우디 아라비아에서 SARS-CoV-2의 전국적인 유행성Article Published on 2021-07-012022-09-12 Journal: Journal of infection and public health [Category] MERS, SARS, 진단, [키워드] addition antibody Asymptomatic Biochemistry caused co-morbidity collected COVID-19 COVID-19 cases COVID-19 infection COVID-19 pandemic COVID-19 patients Critical demographics determine estimate Estimated estimates Evidence groups Hail HCW HCWs healthcare worker healthy blood donor healthy blood donors hypertension in-house ELISA indicate Infection Jeddah Kingdom lab Mild National Non-COVID-19 pandemic Patient positive control Prevalence prevalence of COVID-19 reactive Region regions reported respiratory RT-PCR SARS-CoV-2 SARS-CoV-2 seroprevalence Saudi Arabia sera serological Seroprevalence serum sample serum samples statistical subset virus spread [DOI] 10.1016/j.jiph.2021.04.006 PMC 바로가기 [Article Type] Article
Abnormal Liver Biochemistry Tests and Acute Liver Injury in COVID-19 Patients: Current Evidence and Potential PathogenesisReview Published on 2021-07-012022-11-01 Journal: Diseases [Category] COVID-19, [키워드] Acute acute respiratory syndrome alanine aminotransferase alkaline phosphatase ALP ALT Aspartate aminotransferase AST Biochemistry Cancer Care cause Cell chronic disease cirrhosis Clinical outcome conducted coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients current develop disease disease severity drugs function Health care system Hepatitis hepatocellular Hepatocellular carcinoma hepatocytes hypoxia impacted incidence individual Infection Injury involved liver Liver injury Mortality Pathogenesis pathogenic mechanism Potential Prognostic marker resulting SARS-CoV-2 serum severity Significant systematic review systemic inflammatory response Test tests the disease therapeutic total bilirubin [DOI] 10.3390/diseases9030050 PMC 바로가기 [Article Type] Review
Serum IL-6: A potential biomarker of mortality among SARS-CoV-2 infected patients in Mexico혈청 IL-6: 멕시코의 SARS-CoV-2 감염 환자 사망의 잠재적 바이오마커Article Published on 2021-07-012022-09-11 Journal: Cytokine [Category] SARS, 바이오마커, [키워드] age average average age Biochemistry Biomarker carried cohort study collected correlated correlation COVID-19 COVID-19 case COVID-19 cases COVID-19 patient CRP cutoff value cytokine Cytokine storm Cytokines demographic determine Frequency hospitalized COVID-19 patient hospitalized COVID-19 patients IL-6 IL-6 level immunoassays Indicator individual infected patient infected patients Inflammatory cytokines interleukin interleukin 6 interleukin 6 (IL-6 LDH lymphocyte Lymphocyte count men Mexico Mortality Patient Peninsula Regional reported SARS-CoV-2 SARS-CoV-2 infected patient Sensitivity and specificity Serum level serum levels severity significantly higher survival survival group were measured women Yucatan Yucatan Peninsula [DOI] 10.1016/j.cyto.2021.155543 PMC 바로가기 [Article Type] Article
Effect of artificial liver blood purification treatment on the survival of critical ill COVID-19 patients인공 간 혈액 정화 치료가 코로나19 중환자 생존에 미치는 영향Multicenter Study Published on 2021-07-012022-09-11 Journal: Artificial organs [Category] SARS, 바이오마커, 치료기술, [키워드] 28-day mortality age analyzed artificial liver blood purification average average age baseline data Biochemistry block Blood Blood purification blood routine examination Case-control clinical Clinical data collected comparison control group coronavirus coronavirus disease Coronavirus disease 2019 coronavirus SARS-CoV-2 COVID-19 COVID-19 patient COVID-19 pneumonia Critical Critically ill cytokine Cytokine storm Effect enrolled IL-6 Infection Inflammatory mediators initial symptoms intensification interleukin-6 key factor Laboratory laboratory examinations liver median mediators morbidity Mortality multicenter no difference no significant difference nucleic acid open Patient persistence Pneumonia Pneumonia Severity Index Prospective Study reducing serum Serum IL-6 serum IL-6 level Severe case severe cases Sex significant difference significant increase significantly Stage survival the cytokine storm the patient therapy Treatment treatment group two group two groups Viral viral nucleic acid vital signs [DOI] 10.1111/aor.13884 PMC 바로가기 [Article Type] Multicenter Study
The relationship between serum erythropoietin, hepcidin, and haptoglobin levels with disease severity and other biochemical values in patients with COVID-19COVID-19 환자의 질병 중증도 및 기타 생화학적 수치와 혈청 에리트로포이에틴, 헵시딘, 합토글로빈 수치 간의 관계Comparative Study Published on 2021-07-012022-09-11 Journal: International journal of laboratory hematology [Category] SARS, 바이오마커, [키워드] affected analyzed Anemia biochemical Biochemistry Blood blood cell Cell control group coronavirus disease COVID-19 COVID-19 patient Critical Critical disease Deceased diagnosed with COVID-19 disease severity distribution EPO erythropoietin evaluate ferritin group groups haptoglobin Health health problem healthy volunteer hemoglobin hepcidin hospital Hospitalized ICU intensive care intensive care unit Intubated intubation iron iron homeostasis Iron metabolism mean value metabolism Mild Mortality nine participant Patient patient groups patients with COVID-19 positively correlated red blood cell serum severity shown significantly higher significantly lower Spread SPSS survived the mean the patient Transferrin Variation [DOI] 10.1111/ijlh.13479 PMC 바로가기 [Article Type] Comparative Study
Cross-sectional hospital-based study on the seroprevalence of hepatitis B virus markers among healthcare workers, NWR, CameroonArticle Published on 2021-07-012023-06-12 Journal: BMJ Open [Category] B형 간염, [키워드] Biochemistry Epidemiology public health Virology [DOI] 10.1136/bmjopen-2020-045716 PMC 바로가기
COVID‐19 and the liver – Lessons learnedSupplement Article Published on 2021-06-212022-10-30 Journal: Liver international : official journal of the Inte [Category] COVID-19, MERS, SARS, [키워드] Activation Autoimmune Biochemistry Characteristics characterized cirrhosis coronavirus disease Course COVID‐19 Critical current cytokine production Cytopathic effect disease disease severity elevated Epidemiology Fatty liver hepatocyte high risk hospitalized patient hypoxic Immune cell Immunosuppressive medication include increase in indicated individual Inflammatory response lesson liver Liver damage Liver disease Liver function Liver function test Liver injury Liver transplantation marker mechanism outcome pathological mechanism Patient receiving severity stages susceptibility virus [DOI] 10.1111/liv.14854 PMC 바로가기 [Article Type] Supplement Article
Monitoring Coronavirus Disease 2019: A Review of Available Diagnostic Tools코로나바이러스 질병 2019 모니터링: 사용 가능한 진단 도구 검토Review Published on 2021-06-072022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis Antibody detection Asymptomatic Betacoronavirus Biochemistry Blood caused Chain Reaction clinician colloidal gold coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia cytokine detection rate develop diagnosing diagnostic diagnostics effective ELISA field-effect transistor fluids global public health gold greater help imaging examination immunoassay immunoassays infected individuals Isolation Laboratory laboratory parameter monitoring Next-generation sequencing NGS other coronaviruses patients with COVID-19 PCR analysis plasma Pneumonia Population positive individuals protocol real-time reverse transcriptase–polymerase chain reaction respiratory respiratory tract reverse transcriptase review risk of transmission rRT-PCR SARS-CoV-2 SARS-CoV-2-positive individual Sensitivity and specificity serum severe acute respiratory syndrome Coronavirus species specimen Spread T cell the patient transistor Treatment virus with COVID-19 [DOI] 10.3389/fpubh.2021.672215 PMC 바로가기 [Article Type] Review
Urine biomarkers for the prediction of mortality in COVID-19 hospitalized patientsCOVID-19 입원 환자의 사망률 예측을 위한 소변 바이오마커Article Published on 2021-05-272022-09-10 Journal: Scientific Reports [Category] 바이오마커, 진단, [키워드] 95% CI 95%CI Acute kidney injury Admission Adult patients age AKI albumin alteration AUC Biochemistry Biomarker Biomarkers Blood Care Chronic kidney disease Clinical outcome clinical outcomes cohorts Combination correlated COVID-19 death evaluate evaluated Factor highest highlighting hospital hospital discharge hospitalized patient hospitalized patients ICU ICU admission in-hospital mortality intensive care intensive care unit Kidney disease Lactate lactate dehydrogenase logistic regression model Microbiology Mortality Nephrology observational study Occurrence parameter Patient positive Prognostic factor Prognostic factors reached recruited renal damage Renal involvement renal tubular cell renal tubular cells reported Risk factors ROC curves SARS-CoV-2 serum serum biomarker serum parameter severity sodium specific weight target tubular cells urinary Urine Urology with COVID-19 [DOI] 10.1038/s41598-021-90610-y PMC 바로가기 [Article Type] Article