Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody
Research Article
[키워드] acute respiratory syndrome
addition
administration
against SARS-CoV
antibodies
antibody
approach
bats
binding
binding activity
biochemical
clade
Complete
conserved
coronavirus
COVID-19
COVID-19 pandemic
CoVs
Efficacy
Epidemic
epitope
Evolution
Human
Human monoclonal antibody
in vivo
Lung pathology
Lungs
mouse model
Mouse models
murine model
neutralization breadth
neutralize
neutralized
overlap
pathogenic coronavirus
progeny
Prophylactic
provided
Receptor binding domain
receptor binding site
recognize
sarbecovirus
Sarbecoviruses
SARS-CoV
SARS-CoV-2
SARS-like virus
SARS-related virus
Science
screened
survivor
targeting
the receptor-binding domain
therapeutic
variants
viral replication
yeast
zoonotic spillover
[DOI] 10.1126/science.abf4830 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1126/science.abf4830 PMC 바로가기 [Article Type] Research Article