Omicron BA.2 Lineage, the “Stealth” Variant: Is It Truly a Silent Epidemic? A Literature ReviewOmicron BA.2 계보, "스텔스" 변종: 정말 조용한 전염병입니까? 문헌 검토Review Published on 2022-06-302022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antiviral drugs Asian BA.2 Characteristics coronavirus dominant Epidemic epidemic curve European event FIVE Immunity Infection Lineage lineages literature Monkeypox Neutralizing antibodies neutralizing antibody omicron Omicron variant outbreak pathogenicity predominant public health recombinant variant replication advantage review rising SARS-CoV-2 SARS-CoV-2 variant severe acute respiratory syndrome Coronavirus silence stealth variant. Transmissibility unlikely vaccination Vaccine variant Virological VoC XE [DOI] 10.3390/ijms23137315 PMC 바로가기 [Article Type] Review
Super Dominant Pathobiontic Bacteria in the Nasopharyngeal Microbiota Cause Secondary Bacterial Infection in COVID-19 Patients비인두 미생물총의 슈퍼 우세한 병원성 박테리아는 COVID-19 환자에서 2차 박테리아 감염을 유발합니다Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] Coronavirus, COVID19(2023년), SARS, 치료기술, [키워드] 16S rRNA 16S rRNA gene abundance accounted Acinetobacter aggravate analyzed Bacterial Bacterial infection bacterial pneumonia bacterial specy cause collected Community composed coronavirus disease Coronavirus disease 2019 Corynebacterium Coverage COVID-19 COVID-19 infection COVID-19 patient defined difference disease severity Diversity dominant fatality genus High-throughput sequencing Infection Influenza invasive Lower respiratory tract lower respiratory tract samples microbiota Mild mild COVID-19 patients mild infection mild infections nasopharyngeal nasopharyngeal microbiota nasopharynx pathobiontic bacteria pathogen Patient patients patients with SARS-CoV-2 Pneumonia previous study respiratory infectious disease respiratory tracts responsible rRNA Sample SARS-COV-2 infection secondary secondary bacterial infection secondary bacterial pneumonia Seven severe COVID-19 Severe COVID-19 Infection severe COVID-19 patients severe group severe pneumonia significantly significantly higher Staphylococcus upper upper and lower respiratory tracts upper respiratory tract variety was used [DOI] 10.1128/spectrum.01956-21 PMC 바로가기 [Article Type] Article
Monocytic-Myeloid Derived Suppressor Cells Suppress T-Cell Responses in Recovered SARS CoV2-Infected Individuals단핵구 골수 유래 억제 세포는 회복된 SARS CoV2에 감염된 개인의 T 세포 반응을 억제합니다Article Published on 2022-06-242022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료기술, 치료법, 치료제, [키워드] adaptive immune responses Antigen arginase caused CD11b CD14 CD33 CD57 Cell characterized clinical recovery coronavirus disease Coronavirus disease 2019 correlated COVID-19 CX3CR1 CXCL1 CXCL2 cytokine production Cytokine storm Cytokines depleting dominant downregulated DQA1 DQB1 effector memory expansion Frequency function functional functions Gene Expression HLA-B HLA-DQA1 HLA-DQB1 HLA-DR Hyperinflammatory Hyperinflammatory response IL-6 IL1β immune immune activation immune responses individual individuals infected individual Infection membrane monocytic-myeloid derived suppressor cells mononuclear cell NLRP3 nucleocapsid pathway Pathway analysis Pathways PBMC PD1 peptide peptide pool peptide pools Peripheral blood Peripheral blood mononuclear cells plasma quantity recall recovered regulate remained response RNA-Seq ROS SARS Coronavirus SARS coronavirus 2 SARS CoV2 infection shown spike glycoprotein subset suppress suppresse suppressed suppressor T cell T cell response T cell responses T-cell T-cell responses target TGFβ transcriptional transcriptomic transcriptomic (RNA-Seq). Vaccine viral infection virus [DOI] 10.3389/fimmu.2022.894543 PMC 바로가기 [Article Type] Article
Peptidome Surveillance Across Evolving SARS-CoV-2 Lineages Reveals HLA Binding Conservation in Nucleocapsid Among Variants With Most Potential for T-Cell Epitope Loss in Spike진화하는 SARS-CoV-2 계통에 걸친 펩티도돔 감시, 스파이크에서 T 세포 에피토프 손실 가능성이 가장 큰 변이체 중 뉴클레오캡시드에서 HLA 결합 보존 밝혀Article Published on 2022-06-232022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, 치료법, [키워드] Analysis Antigen B.1.1.529 binding candidate caused CD4+ T cell CD4+ T cells CD8+ comprehensive analysis concern conservation conserved Course COVID-19 disease dominant elicit epitope Epitopes Evidence Genome GISAID heterogeneity HLA immune response immune responses instance interest lineages Loss MOST Mutation N protein N proteins NCBI NIH nucleocapsid omicron pandemic peptide peptides performed Potential predicted Protein protein sequence provided Region remained S protein SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 lineage spike sustained T cells T-cell the N protein the S protein unique vaccination variant variants viral evolution viral variant Viral variants VoC VOCs Volume [DOI] 10.3389/fimmu.2022.918928 PMC 바로가기 [Article Type] Article
Correlation between Population Density and COVID-19 Cases during the Third Wave in Malaysia: Effect of the Delta Variant말레이시아의 제3의 물결 동안 인구 밀도와 COVID-19 사례 간의 상관관계: 델타 변형의 영향Article Published on 2022-06-172022-09-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 변종, [키워드] circulating correlated correlation correlation coefficient COVID-19 COVID-19 case COVID-19 cases cumulative Delta delta variant density described determine distribution dominant Effect higher risk incidence majority Malaysia measure Pearson Population population density spread of COVID-19 Third wave Transmission transmitted Wave [DOI] 10.3390/ijerph19127439 PMC 바로가기 [Article Type] Article
Tracking the molecular evolution and transmission patterns of SARS-CoV-2 lineage B.1.466.2 in Indonesia based on genomic surveillance data게놈 감시 데이터를 기반으로 인도네시아에서 SARS-CoV-2 계통 B.1.466.2의 분자 진화 및 전파 패턴 추적Article Published on 2022-06-162022-09-11 Journal: Virology Journal [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Algorithm Asia B.1.466.2 variant Characteristics circulating Complete Continuous coronavirus country Coverage COVID-19 database delta variant determine distribution dominant downloaded dropped effective Effective population size effective reproduction number Evolution exponential growth genome sequence genomic Genomic surveillance GISAID growth Indonesia Infection island less likelihood Lineage lineages Metadata molecular N439K Non-synonymous mutation Nsp3 nucleotide parameter performed Phylogenesis Phylogenetic analysis Phylogeny phylogeography Population size Prevalence public health reached reconstructed reported Reproduction number SARS-CoV-2 lineage SARS-CoV-2 variant SARS-CoV-2 variants sequence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Single nucleotide variant single nucleotide variants spatiotemporal Spread statistical strain suggested Surveillance surveillance data Transmission transmission pattern transmission patterns Transmission patterns. tropical unique variant Wuhan-Hu-1 [DOI] 10.1186/s12985-022-01830-1 PMC 바로가기 [Article Type] Article
Absence of neutralizing antibodies against the Omicron SARS-CoV-2 variant in convalescent sera from individuals infected with the ancestral SARS-CoV-2 virus or its Gamma variantArticle Published on 2022-06-162022-11-15 Journal: Clinics [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] antibody convalescent sera dominant effective evaluate Gamma Gamma variant Hospitalization in vitro individual individuals Infection Mild moderate Neutralizing antibodies neutralizing antibody Neutralizing antibody response omicron Omicron variant pandemic positive Protective protective antibodies SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 virus sera serum strain Symptom the SARS-CoV-2 variant variants [DOI] 10.1016/j.clinsp.2022.100068 PMC 바로가기
Definition of an Indoor Air Sampling Strategy for SARS-CoV-2 Detection and Risk Management: Case Study in KindergartensSARS-CoV-2 탐지 및 위험 관리를 위한 실내 공기 샘플링 전략의 정의: 유치원 사례 연구Article Published on 2022-06-162022-09-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 치료기술, [키워드] aerosol aerosol transmission Aerosols Air monitoring Analysis bioaerosol sampling case study children Completeness conducted COVID-19 Critical Definition detection dominant droplet droplet transmission Effectiveness Evidence Future hazard identification hygiene Italy kindergarten lack management Prevent reduce Research risk Risk assessment risk assessment and control Risk management sampling sampling plan SARS-CoV-2 SARS-COV-2 infection School Spread standard guideline. Strategy tested Transmission uniformity Ventilation virus virus transmission [DOI] 10.3390/ijerph19127406 PMC 바로가기 [Article Type] Article
Clinical outcomes associated with SARS-CoV-2 Omicron (B.1.1.529) variant and BA.1/BA.1.1 or BA.2 subvariant infection in Southern California Research Published on 2022-06-082022-10-05 Journal: Nature Medicine [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] acute respiratory syndrome Admission B.1.1.529 B.1.617.2 change clinical Clinical outcome coronavirus COVID-19 death Delta delta variant dominant explained hazard ratio healthcare Healthcare system Hospital admission Hospitalization immune protection individual Infection infections intensive care Lower mechanical ventilation occurred omicron outcome progression public health reduced reduced risk risk SARS-CoV-2 SARS-CoV-2 lineage severity Surveillance symptomatic vaccinated against COVID-19 variant [DOI] 10.1038/s41591-022-01887-z [Article Type] Research
High-Throughput Adaptable SARS-CoV-2 Screening for Rapid Identification of Dominant and Emerging Regional Variants우성 및 신흥 지역 변이의 신속한 식별을 위한 처리량이 높은 적응형 SARS-CoV-2 스크리닝Article Published on 2022-06-072022-09-11 Journal: American journal of clinical pathology [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age approach Care Chain Reaction coronavirus Cycle threshold value Delta delta variant detect detection dominant Dynamic system E484K Effectiveness genotyping Health Health care Health care system health system highlight hospital identification IMPROVE Increases Infection median pandemic polymerase chain reaction Rapid reactive reduced Regional RT-PCR SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants screened Screening screening program selective Sequencing severe acute respiratory syndrome Coronavirus severe disease strain Surveillance Targeted testing Transmissibility utility variant Variant identification variant of concern variant screening variants viral sequence [DOI] 10.1093/ajcp/aqab212 PMC 바로가기 [Article Type] Article