genomes – Page 13 – Communicable Diseases Research

Genomic and Phenotypic Analysis of COVID-19-Associated Pulmonary Aspergillosis Isolates of Aspergillus fumigatus

Aspergillus fumigatus의 COVID-19 관련 폐 아스페르길루스증 분리물의 게놈 및 표현형 분석

Research Article

Published on 2021-06-092022-09-10
Journal: Microbiology Spectrum [Category] MERS, SARS, 변종, 유전자 메커니즘,

SARS-CoV-2 mutations in Brazil: from genomics to putative clinical conditions

브라질의 SARS-COV-2 돌연변이 : 유전체학에서 추정 임상 조건까지

Article

Published on 2021-06-072022-09-10
Journal: Scientific Reports [Category] MERS, SARS, 변종, 유전자 메커니즘, 치료제,

Interactive SARS-CoV-2 mutation timemaps

대화형 SARS-CoV-2 돌연변이 타임맵

Brief Report

Published on 2021-06-032022-09-11
Journal: F1000Research [Category] MERS, 변종,

V367F Mutation in SARS-CoV-2 Spike RBD Emerging during the Early Transmission Phase Enhances Viral Infectivity through Increased Human ACE2 Receptor Binding Affinity

초기 전파 단계에서 나타나는 SARS-CoV-2 스파이크 RBD의 V367F 돌연변이는 증가된 인간 ACE2 수용체 결합 친화도를 통해 바이러스 감염성을 향상시킵니다

Virus-Cell Interactions

Published on 2021-06-022022-09-10
Journal: Journal of Virology [Category] SARS, 변종, 유전자 메커니즘, 진단,

[키워드] ACE2 ACE2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affinity Analysis analyzed angiotensin assays binding binding affinity caused circulating coronavirus CoV COVID-19 COVID-19 pandemic Critical domain dominant dominant mutations drug ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay Genome genomes hot spot Human human ACE2 human Angiotensin-converting enzyme humans in silico Increased indicated infect infectious Infectivity MDs molecular dynamics Molecular dynamics simulation molecular dynamics simulations mutant Mutation nonsynonymous Novel coronavirus pandemic of COVID-19 pangolin pangolin CoV phase Phylogenetic analysis provide Pseudotyped virus RBD RBD mutation RBD mutations receptor Receptor binding Receptor-binding domain (RBD) Recombination Research respiratory SARS-CoV-2 SARS-CoV-2 isolate SARS-CoV-2 isolates SARS-CoV-2 RBD SARS-CoV-2 spike protein SARS-CoV-2 variant selection pressure severe acute respiratory syndrome Coronavirus spike spike mutation spike mutations Spike protein Support surface plasmon surface plasmon resonance Surveillance sustained the RBD the SARS-CoV-2 trajectory Transmission V367F Vaccine Vaccines variant variants Viral viral infectivity viral tropism zoonotic infections zoonotic origin
[DOI] 10.1128/JVI.00617-21 PMC 바로가기 [Article Type] Virus-Cell Interactions

Extensive C->U transition biases in the genomes of a wide range of mammalian RNA viruses; potential associations with transcriptional mutations, damage- or host-mediated editing of viral RNA

Research Article

Published on 2021-06-012022-10-29
Journal: PLoS Pathogens [Category] COVID-19, MERS, SARS,

[키워드] accounted adaptive aligned ANOVA antiretroviral APOBEC association Caliciviridae change coding region Combination component contribute Coronaviridae dataset disease driven by Evidence Evolution Extensive fixation Flaviviridae Frequency Generation time genetic change Genome genome sequence genomes genomic HCV HIV-1 homoplasy identity infecting investigated mammalian mammals mechanism mechanisms multivariable analysis Mutation mutations Neutral Occurrence parameter phylogenetically provide random replicate Replication reported representing retrovirus RNA RNA secondary structure RNA virus RNA viruses SARS Coronavirus SARS-CoV-2 sequence sequence variability significantly subset Substitution thought transcriptional upstream Viral RNA virus while
[DOI] 10.1371/journal.ppat.1009596 PMC 바로가기 [Article Type] Research Article

SARS-CoV-2 Infections and Viral Isolations among Serially Tested Cats and Dogs in Households with Infected Owners in Texas, USA

SARS-CoV-2 감염 및 미국 텍사스주에서 감염된 소유자가 있는 가정에서 연속 테스트를 거친 고양이와 개 사이의 바이러스 격리

Article

Published on 2021-05-192022-09-01
Journal: Viruses [Category] SARS, 변종, 진단,

[키워드] animals Asymptomatic cats circulating conducted Critical dog dogs ecological epidemiological Evidence evidence of Follow-up Genome genomes Health household household transmission include initial majority National Neutralizing antibodies no evidence of occur PCR-positive people with COVID-19 persistence positive reservoirs respiratory reverse zoonosis RT-PCR sampling SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody sequence Sequencing seroreversion Seven Swab transmission of SARS-CoV-2 understanding unique USA variant Viral Viral RNA virus virus isolation whole-genome sequences
[DOI] 10.3390/v13050938 PMC 바로가기 [Article Type] Article

Applying Genomic Epidemiology to Characterize a COVID-19 Outbreak in a Developmentally Disabled Adult Group Home Setting, Arizona

애리조나주 발달 장애 성인 그룹 가정 환경에서 COVID-19 발병을 특성화하기 위해 게놈 역학 적용

Public Health

Published on 2021-05-132022-09-11
Journal: Frontiers in Public Health [Category] MERS, SARS, 유전자 메커니즘,

Use of Genomics to Track Coronavirus Disease Outbreaks, New Zealand

뉴질랜드, 코로나바이러스 질병 발병을 추적하기 위한 유전체학 사용

Research

Published on 2021-05-012022-09-10
Journal: Emerging Infectious Diseases [Category] SARS, 유전자 메커니즘,

Global and local mutations in Bangladeshi SARS-CoV-2 genomes

방글라데시 SARS-CoV-2 게놈의 글로벌 및 로컬 돌연변이

Article

Published on 2021-05-012022-09-11
Journal: Virus research [Category] SARS, 변종,

[키워드] acute respiratory syndrome Amino acid amino acid change Analysis average Bangladesh circulating clade coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 D614G D614G mutation Deletion deletions Epidemiology European G614 variant Genome genomes indicated insertion isolates Local Missense mutations Mutation mutations ORF1 ORF1ab ORF3a Pathogenesis phylogenetic analyses predominant prevalent protein level protein levels reported respiratory RNA SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomic sequences SARS-CoV-2 virus SARS-CoV-2 viruses sequence sequences Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly higher spike glycoprotein synonymous transmitted unique Variation variations viruses whole genome whole genomes Whole-genome sequence
[DOI] 10.1016/j.virusres.2021.198390 PMC 바로가기 [Article Type] Article

Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and Other Coronaviruses: A Genome-wide Comparative Annotation and Analysis

Comparative Study

Published on 2021-05-012022-10-04
Journal: Molecular and cellular biochemistry [Category] SARS, 신약개발,

[키워드] alleviate Analysis analyzed annotation cause Comparative coronavirus coronavirus 2 COVID-19 death develop diagnostic difficulty in breathing disease dry cough eight facilitate Factors Fatality rate Fever Genome genome map genomes genomic geographical location Host Human identify IFR include infecting Infection involved less MERS Middle East Mild Mutation mutational rate novel Other other coronavirus outbreak pandemic peptide Phylogenetic analysis Phylogenomics polymorphism predicted rate of infection researcher respiratory SARS-CoV SARS-CoV2 sequenced severe cases severe respiratory illness similarity SNP SNPs SSR Symptom transcriptional UTR UTR. virus virus infection WHO whole genome World Health Organization Wuhan
[DOI] 10.1007/s11010-020-04027-8 PMC 바로가기 [Article Type] Comparative Study