Evidence of SARS-CoV-2-Specific T-Cell-Mediated Myocarditis in a MIS-A CaseMIS-A 사례에서 SARS-CoV-2-특이적 T-세포 매개 심근염의 증거Case Reports Published on 2021-12-092022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 cd-hit CDR3 sequences clone collected coronavirus Diagnosis died Epitopes evidence of Gut healthy heart Inflammation Inflammatory macrophages MIS-A myocardial necrosis myocarditis Necrosis respiratory SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-CoV-2 epitopes SARS-CoV-2 RNA selected sequence Sequencing severe acute respiratory syndrome Coronavirus specimen syndrome T cell receptor (TCR) T-cell T-cell receptor T-cells target TCR TCRs tested tissue-repair [DOI] 10.3389/fimmu.2021.779026 PMC 바로가기 [Article Type] Case Reports
COVID-19: A New Horizon in Congenital Heart DiseasesPediatrics Published on 2021-12-082022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] 95% CI ACE ACE inhibitor addition analyzed angiotensin receptor blocker cardiac disorder Cardiac surgery CHD Chest CT children collected congenital congenital heart disease coronavirus disease COVID-19 COVID-19 infection COVID-19 pandemic demographics demonstrated died discharged disease enzyme female heart high risk Horizon ICU admission Infection infections inhibitor intensive care IQR lung involvement median age median interval myocarditis New not different Odds ratio pandemic participant Patient pediatric Physical examination positive prevalence of COVID-19 previous study pulmonary hypertension recruited reported risk RT-PCR significantly higher surgical susceptible suspicious patient symptomatic the healthy the patient Two patient worsening [DOI] 10.3389/fped.2021.582043 PMC 바로가기 [Article Type] Pediatrics
The risk of transmission of the novel coronavirus (SARS-CoV-2) with human heart valve transplantation: evaluation of cardio-vascular tissues from two consecutive heart donors with asymptomatic COVID-19인간 심장 판막 이식으로 신종 코로나바이러스(SARS-CoV-2) 전파 위험: 무증상 COVID-19가 있는 2명의 연속 심장 기증자의 심혈관 조직 평가Case Reports Published on 2021-12-012022-09-11 Journal: Cell and tissue banking [Category] SARS, 치료기술, [키워드] ACE2 Allograft Aortic valve Asymptomatic Asymptomatic COVID-19 Cardiomyopathy clinically coronavirus COVID-19 cytoplasmic dilated cardiomyopathy donation Donor donors eosinophilic myocarditis heart Heart transplantation Heart valves hearts Homograft hypertrophic hypertrophic cardiomyopathy immunostaining life-threatening LIGHT light microscopy living donors Microscopy Mild mitral mitral valve myocarditis Myocardium Novel coronavirus nucleus Obstructive performed positive Presence pulmonary Pulmonary valve receiving Research risk risk of transmission RT-PCR SARS-CoV-2 SARS-CoV-2 test tested tissue Tissue banking Tissue Transplantation tissues Transmission tricuspid tricuspid valve Viral transmission virus virus transmission wall [DOI] 10.1007/s10561-021-09913-z PMC 바로가기 [Article Type] Case Reports
Disentangling post-vaccination symptoms from early COVID-19Research paper Published on 2021-12-012022-10-04 Journal: EClinicalMedicine [Category] 치료기술, [키워드] 1:1 Asymptomatic AUC, area under the curve bMEM, Bayesian mixed-effect model BMI, Body mass index BNT162b2 ChAdOx1 nCoV-19 chronic CI, Confidence interval clinical information Community Comorbidities conducted cough Council COVID COVID-19 COVID-19 detection COVID-19, Coronavirus disease 2019 criteria Critical CSS CSS, COVID Symptoms Study demographic Department DI, Data invalid Early detection Engineering fatigue Fever finding foundation funding headache heart identifying individual infection control injection IQR, inter quartile range KCL, King's College London LFAT, Lateral flow antigen test Local LR, Logistic Regression Medical Research Council Mobile technology MOST myalgia NHS UK, National Health Service of the United Kingdom O-AZ, Oxford-AstraZeneca adenovirus-vectored vaccine overlap Oxford-AstraZeneca adenovirus-vectored vaccine participant Participants PB, Pfizer-BoiNTech mRNA vaccine Pfizer-BioNTech mRNA vaccine positive post-vaccination symptom presenting Prevent profile prospective observational study public health reduce reported symptom RF, Random forest ROC, Receiver operating curve rtPCR, Reverse transcription polymerase chain reaction SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test SARS-CoV-2, Severe acute respiratory syndrome-related coronavirus-2 Science Self-reported symptoms sensitivity Seven severe acute respiratory syndrome‐related coronavirus 2 (SARS-CoV-2) severe acute respiratory syndrome‐related coronavirus 2 (SARS-CoV-2) Side-effect Side-effects Spread Symptom Symptoms systemic symptom tested UK, United Kingdom of Great Britain and Nothern Ireland vaccination were recorded with COVID-19 [DOI] 10.1016/j.eclinm.2021.101212 PMC 바로가기 [Article Type] Research paper
Heart, Lung and Circulation in the COVID-19 Era: About COVID-19, Not Just About COVID-19Editorial Published on 2021-12-012022-10-05 Journal: Heart, Lung and Circulation [Category] Coronavirus, SARS, 유전자 메커니즘, [키워드] Bibliometrics Cardiovascular innovations COVID-19 heart Position statements [DOI] 10.1016/j.hlc.2021.10.001 [Article Type] Editorial
Detailed Analyses of the Expression Patterns of Potential Severe Acute Respiratory Syndrome Coronavirus 2 Receptors in the Human Heart Using Single-Nucleus RNA SequencingCardiovascular Medicine Published on 2021-11-302022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] ACE2 ACE2 expression ACE2-positive cell acute respiratory syndrome adipocyte adipocytes analyzed ANPEP BSG cardiac injury cardiovascular complication Cell cell entry receptor cell types cells cellular receptor cellular receptors Characteristics clinical study coronavirus coronavirus 2 coronavirus disease COVID-19 determinant distribution expression expression features expression level fibroblast Frequency heart HSPA5 Human indicated Infection Injury Intervention investigated involved KREMEN1 mechanism NRP1 patients with COVID-19 pattern pericyte pericytes Potential receptor respiratory RNA RNA-Seq SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptor sequence similarity significantly significantly higher single-cell level subset susceptibility susceptible target transcriptional ventricular virus receptor [DOI] 10.3389/fcvm.2021.757362 PMC 바로가기 [Article Type] Cardiovascular Medicine
Is cardiac involvement prevalent in highly trained athletes after SARS-CoV-2 infection? A cardiac magnetic resonance study using sex-matched and age-matched controlsOriginal Research Published on 2021-11-292022-10-28 Journal: British journal of sports medicine [Category] COVID-19, COVID19(2023년), Fulltext, MERS, SARS, [키워드] age-matched control alteration Antibody test Asymptomatic Athletes athletic consequence controls COVID-19 cut-off diagnosed elevated Frequency functional greater groups healthy heart Immunoglobulin IQR less male median moderate myocarditis no difference objective parameters patients PCR prevalent protocol remained Result SARS-CoV-2 SARS-COV-2 infection sequence serum Swab test Symptom symptom severity symptomatic infection [DOI] 10.1136/bjsports-2021-104576 PMC 바로가기 [Article Type] Original Research
Corona Virus Disease 2019 (COVID-19) as a System-Level Infectious Disease With Distinct Sex Disparities2019년 코로나 바이러스 질병(COVID-19)은 성별 격차가 뚜렷한 시스템 수준 전염병Review Published on 2021-11-292022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커, [키워드] abnormality ACE2 acute respiratory syndrome coronavirus Affect angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 clotting system Coagulation Corona coronavirus COVID COVID-19 cytokine Cytokine storm Cytokine storms disparity endothelial cells endotheliopathy Endothelium explain expressed fatigue global pandemic heart help host cells hyper-inflammation hypercoagulability Immune cell immune cells immune system Immunity increased the risk interconnectedness kidney lead lung men Mortality multi-organ dysfunction neurons outcome physical physical fitness RAS recruitment reduced Renin renin-angiotensin system respiratory resulting SARS-CoV-2 SARS-CoV-2 entry severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity Sex Symptoms System Thromboembolism thrombosis Venous thrombosis [DOI] 10.3389/fimmu.2021.778913 PMC 바로가기 [Article Type] Review
Heart Rate in Patients with SARS-CoV-2 Infection: Prevalence of High Values at Discharge and Relationship with Disease SeverityArticle Published on 2021-11-282022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI Admission age arrhythmia autonomic bpm clinical history collected data Course COVID COVID-19 COVID-19 patient decrease defined discharge discharged disease dysfunction elevated enrolled evaluate Gender Haemoglobin heart heart rate hospital ICU Infection infection severity intensive care unit Laboratory test Linear model male marker mechanical ventilation occur patients hospitalized persistence pharmacological treatment Pneumonia predictor Prevalence prevalent quartile Rate relationship SARS-CoV-2 SARS-CoV2 infection Sepsis severe disease Significant strongly related subject Tachycardia the disease value variable vital signs [DOI] 10.3390/jcm10235590 PMC 바로가기 [Article Type] Article
The Impact of COVID-19 Pandemic on Management and Outcome in Patients with Heart FailureArticle Published on 2021-11-272022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] absence addressed affected age cardiovascular Care Clinical management Cohort Comorbidities competing COVID-19 COVID-19 pandemic death deaths decrease diabete Diagnosis died disease Effect evaluated failure functional Health Health Service heart heart failure Hospitalization hospitalizations Impact infected with COVID-19 initial lockdowns Male sex management medical service morbidity and mortality Mortality mortality rate Non-COVID-19 obesity outcome overall mortality pandemic Patient reduced renal dysfunction replaced respiratory infection SARS-CoV-2 significantly social distancing study period survival rate were infected with COVID-19 [DOI] 10.3390/jcm10235577 PMC 바로가기 [Article Type] Article