SARS-CoV-2 Cellular Infection and Therapeutic Opportunities: Lessons Learned from Ebola VirusReview Published on 2021-01-182022-10-31 Journal: Membranes [Category] COVID-19, [키워드] antibodies antivirals cellular cellular receptor clinical testing clinical therapy combating coronavirus SARS-CoV-2 Disease progression Ebola Ebola virus effective endocytic endocytosis facilitated help highly pathogenic host cell infect infected individuals Infection knowledge lesson life-threatening mechanism New coronavirus overlap Pandemics replicate Replication SARS-CoV-2 subsequent target cells Vaccine Vaccines viral entry virus viruses [DOI] 10.3390/membranes11010064 PMC 바로가기 [Article Type] Review
MERS-CoV: epidemiology, molecular dynamics, therapeutics, and future challengesReview Published on 2021-01-182022-10-28 Journal: Annals of Clinical Microbiology and Antimicrobials [Category] COVID-19, MERS, [키워드] affected Betacoronavirus challenges changes in Cluster Community coronavirus coronavirus 2 Cross-species transmission effective Epidemic Epidemiology event Factor Fatality rate genetic variability Genome highest highly pathogenic immunological inherent membrane MERS MERS-CoV Middle East molecular molecular dynamics Nosocomial infection nucleocapsid nucleotide occur open reading frames outbreak pandemic pathology Phylogeny predicted progression Protein Region reported Research respiratory respiratory sample SARS-CoV-2 Saudi Arabia Seven spike Spike protein structural proteins subsequent therapeutic Therapeutics Transmission viral infection zoonotic zoonotic transmission [DOI] 10.1186/s12941-020-00414-7 PMC 바로가기 [Article Type] Review
Evaluation of SARS-CoV-2 neutralizing antibodies using a vesicular stomatitis virus possessing SARS-CoV-2 spike proteinSARS-CoV-2 스파이크 단백질을 보유하는 수포성 구내염 바이러스를 이용한 SARS-CoV-2 중화항체 평가Research Published on 2021-01-122022-09-01 Journal: Virology Journal [Category] 진단, [키워드] Antibody titer Antibody titers biosafety biosafety level BSL-2 laboratory BSL-3 BSL2 chemiluminescence circumvent collected conditions coronavirus correlated COVID-19 Donor donors ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated examined expressing full length genus highly pathogenic hospitalized patient hospitalized patients Human IFA immunofluorescence assay Infection Live virus luciferase neutralization Neutralization assay neutralization test Neutralizing antibodies neutralizing antibody Novel coronavirus Occurrence pathogen PCR-negative performed Pseudotyped virus reduction Result SARS-CoV SARS-CoV-2 SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody SARS-CoV-2 spike protein sensitivity serum serum sample serum samples specificity Spike protein Spike proteins vesicular stomatitis virus virus infection VSV Whole blood with COVID-19 [DOI] 10.1186/s12985-021-01490-7 PMC 바로가기 [Article Type] Research
JAK-inhibitor and type I interferon ability to produce favorable clinical outcomes in COVID-19 patients: a systematic review and meta-analysisResearch Article Published on 2021-01-112022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, [키워드] 95% CI Antiviral candidate Clinical outcome conducted controls Coronaviruses COVID-19 COVID-19 patient COVID-19 patients cytokine release discharge disease Efficacy estimate highly pathogenic hospital discharge Human ICU admission indicated infection control interferon interferon treatment investigator janus medRxiv Meta-analysis Mortality non-randomized novel Novel coronavirus pandemic positive Randomized RCT recipient reduced respiratory infection Result risk SARS-CoV-2 searched significantly significantly increased Spread standard treatment supplementary material systematic review therapy These data treated Treatment Treatment outcome trials Type type I interferon viral infection virus while [DOI] 10.1186/s12879-020-05730-z PMC 바로가기 [Article Type] Research Article
H2V: a database of human genes and proteins that respond to SARS-CoV-2, SARS-CoV, and MERS-CoV infectionDatabase Published on 2021-01-072022-10-27 Journal: BMC Bioinformatics [Category] COVID-19, [키워드] accelerate Analysis Antiviral approved article caused cellular and molecular cellular pathway collected confirmed case coronavirus Coronavirus infection country COVID-19 pandemic database death develop expected Gene highly pathogenic human gene identify Impact impair Infection information measure MERS-CoV MERS-CoV infection molecular Novel coronavirus powerful tool Protein proteomic provide public health respond response Result SARS-CoV SARS-CoV-2 targets transcriptomic Treatment Vaccine viral infection viral pathogenesis viruses WHO [DOI] 10.1186/s12859-020-03935-2 PMC 바로가기 [Article Type] Database
H2V: a database of human genes and proteins that respond to SARS-CoV-2, SARS-CoV, and MERS-CoV infectionH2V: SARS-CoV-2, SARS-CoV, MERS-CoV 감염에 반응하는 인간 유전자 및 단백질 데이터베이스Database Published on 2021-01-072022-09-01 Journal: BMC Bioinformatics [Category] 유전자 메커니즘, 진단, [키워드] accelerate Analysis Antiviral antiviral agent approved article caused cellular and molecular cellular pathway cellular pathways collected confirmed case coronavirus Coronavirus infection Coronavirus infections country CoV infection COVID-19 pandemic database death develop Economy expected Gene highly pathogenic human body human gene human genes identify Impact impair Infection information measure MERS MERS-CoV MERS-CoV infection molecular Novel coronavirus powerful tool Protein proteomic provide public health respond response Result SARS-CoV SARS-CoV-2 Society targets these viruses transcriptomic Treatment Vaccine Viral viral infection viral infections viral pathogenesis viruses WHO [DOI] 10.1186/s12859-020-03935-2 PMC 바로가기 [Article Type] Database
H2V: a database of human genes and proteins that respond to SARS-CoV-2, SARS-CoV, and MERS-CoV infectionDatabase Published on 2021-01-072022-10-27 Journal: BMC Bioinformatics [Category] Coronavirus, COVID-19, Fulltext, MERS, [키워드] accelerate Analysis Antiviral approved article caused cellular and molecular cellular pathway collected confirmed case coronavirus Coronavirus infection country COVID-19 pandemic database death develop expected Gene highly pathogenic human gene identify Impact impair Infection information measure MERS-CoV MERS-CoV infection molecular Novel coronavirus powerful tool Protein proteomic provide public health respond response Result SARS-CoV SARS-CoV-2 targets transcriptomic Treatment Vaccine viral infection viral pathogenesis viruses WHO [DOI] 10.1186/s12859-020-03935-2 PMC 바로가기 [Article Type] Database
Use of the informational spectrum methodology for rapid biological analysis of the novel coronavirus 2019-nCoV: prediction of potential receptor, natural reservoir, tropism and therapeutic/vaccine targetBrief Report Published on 2021-01-062022-10-31 Journal: F1000Research [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV ACE2 acute respiratory syndrome affecting Analysis biological activity candidate cell entry coronavirus domain drug Epidemic highly pathogenic Host humans identify in silico analysis indicate indicated Infection MERS methodology Middle East modulating new virus Novel coronavirus pandemic Pathogenesis performed Protein putative receptor receptor S1 protein SARS SARS-CoV SARS-CoV-2 suggested syndrome targets the SARS-CoV-2 therapeutic Treatment Vaccine viral infection virus Wuhan coronavirus Wuhan, China [DOI] 10.12688/f1000research.22149.4 PMC 바로가기 [Article Type] Brief Report
The cytokine storm and COVID-19사이토카인 폭풍과 코로나19Review Published on 2021-01-012022-09-11 Journal: Journal of medical virology [Category] Fulltext, MERS, 임상, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Antiviral cause of death caused Clinical data close contact component coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity cytokine Cytokine storm death feature Features global pandemic highly pathogenic literature review pathophysiological mechanisms Patient public health respiratory respiratory droplet Respiratory droplets SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe COVID-19 severity Spread the cytokine storm Treatment Vaccine with COVID-19 Wuhan Wuhan, China [DOI] 10.1002/jmv.26232 PMC 바로가기 [Article Type] Review
COVID-19 – The clinical consequences of social isolation and the relation with sleep bruxism and comorbiditiesOverviews Published on 2021-01-012022-10-28 Journal: Sleep Science [Category] COVID-19, [키워드] adverse effect Anxiety Anxiety obesity association Bruxism cause clinical condition clinical consequence Comorbidity conditions coronavirus COVID-19 COVID-19 disease disease drug Gastroesophageal reflux highly pathogenic Isolation overlapping pandemic patients professional severity Sleep bruxism sleep quality social isolation the disease [DOI] 10.5935/1984-0063.20210004 PMC 바로가기 [Article Type] Overviews