AKR1B10, One of the Triggers of Cytokine Storm in SARS-CoV2 Severe Acute Respiratory Syndrome
AKR1B10, SARS-CoV2 중증 급성 호흡기 증후군에서 사이토카인 폭풍의 방아쇠 중 하나
Article
Published on
Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘,
Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘,
[키워드] Activation
Acute respiratory failure
AKR1B10
Analysis
biological plausibility
cell types
contribute
COVID-19
cytokine
Cytokine storm
Cytokines
died
drug treatment
enzyme
experiment
expression
extracellular vesicle
Extracellular vesicles
Factor
form
gene encoding
highlight
hospitalised COVID-19 patient
hospitalised COVID-19 patients
Hypothesis
identify
IL-1β
IL-6
increased expression
induce
Inflammation
inhibitor
interleukin
interleukin-1β
interleukin-6
involved
lipopolysaccharides
LPS
lung
lung cells
Macrophage
macrophages
management
measurement
modulation
Occurrence
outcomes
over-expression
Patient
pharmacological target
Preventing
pro-inflammatory
pro-inflammatory cytokine
pro-inflammatory cytokines
Protein
reduced
reducing
Reductase
respiratory
Respiratory failure
SARS-CoV2
secreted
sera
severe forms of COVID-19
severity
significantly
storm
systemic impact
the cytokine storm
the disease
TNF α
TNFα
transcriptomic data
transferred
treated
Trigger
Tumor
tumor necrosis
tumor necrosis factor
[DOI] 10.3390/ijms23031911 PMC 바로가기 [Article Type] Article
[DOI] 10.3390/ijms23031911 PMC 바로가기 [Article Type] Article