Intubated – Page 13 – Communicable Diseases Research

Successful treatment of intubation-induced severe neurogenic post-extubation dysphagia using pharyngeal electrical stimulation in a COVID-19 survivor: a case report

Case Report

Published on 2021-03-222022-10-30
Journal: Journal of Medical Case Reports [Category] COVID-19, SARS,

Interleukin-6 blocking agents for treating COVID-19: a living systematic review

COVID-19 치료를 위한 인터루킨-6 차단제: 살아있는 체계적인 검토

Meta-Analysis

Published on 2021-03-182022-09-11
Journal: The Cochrane database of systematic reviews [Category] 임상, 진단,

[키워드] 95% CI adverse event adverse events age all-cause mortality anti-IL6 approach articles available data average baseline benefit Bia blocking agent blocking agents Brazil can not Care certainty certainty of evidence China clinical Clinical improvement Cochrane COVID-19 Study Register collected data conducted coronavirus disease Coronavirus disease 2019 COVID-19 Critical Critical disease Data collection death defined disease disease severity Efficacy and safety eight evaluate evaluated Evidence excluded FIVE Follow-up France Health Organization heterogeneity hospital discharge identify IL-6 IL-6 blocking Immune system dysfunction immunosuppressive incidence Inclusion individual individual patient data meta-analyses Inflammation interleukin interleukin 6 interleukin 6 (IL-6 Intubated intubated patient intubated patients Italy male mechanical ventilation Meta-analysis methodology Mild moderate Mortality multicentre nine no increase not intubated organ support Other outcomes outcome outcomes oxygen participant Participants Patient patient data patients with COVID-19 peer-reviewed people with COVID-19 Placebo platform Platform trial progression proportion protocol randomised randomised controlled trial Randomised controlled trials ranged RCT RCTs reduce Registered registry reported risk of bia Safety sarilumab score searched Selection Serious Adverse Event Serious Adverse Events Seven severe coronavirus disease severity siltuximab standard care Standard of care subgroups of patient systematic review Tocilizumab Tolerance Treatment Trial trial participant trial participants trials unlikely USA WHO World Health Organization
[DOI] 10.1002/14651858.CD013881 PMC 바로가기 [Article Type] Meta-Analysis

Clinical and epidemiological characteristics and outcomes of patients hospitalized for COVID-19 in Douala, Cameroon

Observational Study

Published on 2021-03-082022-10-04
Journal: The Pan African Medical Journal [Category] MERS, 임상,

[키워드] accounted Admission age analysed Analysis analyzed average Cameroon Characteristics clinical Clinical characteristics Clinical improvement conducted coronavirus disease cough country COVID-19 COVID-19 pandemic diabete disease Dyspnea Effect effective epidemiological Epidemiology Fever globe high mortality Hospital stay Hospitalised patients in-hospital mortality intensive care Intubated male management medical condition mortality rate outcome outcomes oxygen supplementation parameter Patient patients hospitalized Pneumonia polymerase chain presenting protocols radiological features real-time reverse transcriptase reducing reported resources Result retrospective Spread Wuhan
[DOI] 10.11604/pamj.2021.38.246.28169 PMC 바로가기 [Article Type] Observational Study

Antihypertensive Drugs and COVID-19 Risk: A Cohort Study of 2 Million Hypertensive Patients

Observational Study

Published on 2021-03-032022-10-05
Journal: Hypertension (Dallas, Tex. : 1979) [Category] SARS, 임상,

[키워드] ACE ACE inhibitor ACE inhibitors angiotensin receptor blocker Angiotensin receptor blockers Angiotensin-converting enzyme angiotensin-converting enzyme inhibitors antihypertensive ARB ARBs associations blocker calcium channel blockers cardiovascular disease CCB CCBs chronic respiratory disease Cohort coronavirus disease COVID-19 COVID-19 hospitalization database diabetes died drug end point Evidence examined excluded French hazard ratio Hospital stay Hospitalization Hospitalized hypertension hypertensive patient hypothese hypotheses inhibitor insurance Intubated limit lower risk Mortality Patient patients treated pharmacoepidemiology positive prevalent primary end point raise receptor renal risk treated
[DOI] 10.1161/HYPERTENSIONAHA.120.16314 PMC 바로가기 [Article Type] Observational Study

Severe acute respiratory syndrome coronavirus 2-induced acute aortic occlusion: a case report

Case Report

Published on 2021-03-022022-10-30
Journal: Journal of Medical Case Reports [Category] COVID-19, SARS,

[키워드] absence acute respiratory syndrome Antibiotics Aortic occlusion appear arteries C-reactive protein Care Case report coronavirus coronavirus disease COVID-19 D-dimer died dry cough elevated evaluated febrile ferritin fevers Healthcare provider Hospitalization hypoxemic immune increasingly Infection inflammatory cascades initiated Injury intensive care Intubated lactate dehydrogenase male non-rebreather mask outcome past medical history Patient Pneumonia polymerase chain positive positive airway pressure proceed promote prothrombotic prothrombotic state reverse transcription Shortness of breath subumbilical supplemental oxygen Support Symptom the patient thrombosis thrombotic complication Thrombotic complications Vascular vascular disease vascular tissue venous X-ray
[DOI] 10.1186/s13256-021-02692-x PMC 바로가기 [Article Type] Case Report

A multicenter study on epidemiological and clinical characteristics of 125 newborns born to women infected with COVID-19 by Turkish Neonatal Society

Clinical Trial

Published on 2021-03-012022-10-04
Journal: European journal of pediatrics [Category] 임상,

[키워드] Anxiety breast milk Breastfeeding Care Cesarean section Clinical characteristics conducted COVID-19 died disease severity enrolled epidemiological evaluate expressed Impact infected with COVID-19 information intensive care intensive care unit Intubated intubation Isolation room lack Limited Maternal mechanical ventilation Mortality mother multicenter multicenter cohort study Neonatal Neonates Newborn NICU outcome outcomes parent positive positive RT-PCR Pregnancy pregnant women Preterm birth risk Sample SARS-CoV-2 Society Support tracheal Transmission Turkey with COVID-19 women
[DOI] 10.1007/s00431-020-03767-5 PMC 바로가기 [Article Type] Clinical Trial

Tracheal Tube Obstruction Due to Hemoptysis Associated With Pulmonary Infarction in a Patient With Severe COVID-19 Pneumonia

Emergency Medicine

Published on 2021-02-272022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] accompanied acute respiratory syndrome Admission Anticoagulant anticoagulant therapy Blood Case report coronavirus COVID-19 Cytokine storm decrease Diagnosis discharged Disseminated intravascular coagulation dropped eight endotracheal tube excessive immune response extracorporeal membrane oxygenation Factor hemoptysis hospital Hypoxemia hypoxic incidence Infarction Inflammation initiated intensive care Intubated Japanese obstruction oxygen saturation PaO Patient patients with COVID-19 Pharyngeal swab positive pulmonary pulmonary embolism (PE) risk of infection severe coronavirus disease Severe COVID-19 pneumonia suction suggested Support tested the patient thrombotic complication Thrombotic complications tracheal tube tube ventilator Volume VV-ECMO were used
[DOI] 10.7759/cureus.13599 PMC 바로가기 [Article Type] Emergency Medicine

From SARS-CoV-2 hematogenous spreading to endothelial dysfunction: clinical-histopathological study of cutaneous signs of COVID-19

SARS-CoV-2 혈행성 확산에서 내피 기능 장애까지: COVID-19의 피부 징후에 대한 임상-조직병리학적 연구

Case Reports

Published on 2021-02-252022-09-11
Journal: Diagnostic Pathology [Category] MERS, 치료기술,

[키워드] Activation Arterioles Atypical Atypical pneumonia Azithromycin Capillaries capillary Case report caused Chest Chest CT Coagulopathy conducted correlation COVID-19 Cytokines dermatitis died disorder Disruption edema edematous endothelial Endothelial cell endothelial cells Endothelial dysfunction endothelial integrity Endothelial swelling ENhance erythematous erythroderma expression extravasation granulocyte Ground-glass opacities healing hematogenous histological Histopathology Hospitalized Hydroxychloroquine immune system impairment inflammatory cell inflammatory cells initiated Injury intensive care unit Intubated Lopinavir Lopinavir-ritonavir lung microvascular permeability Morphological Nasopharyngeal swab Neck non-specific papillary dermis Patient perivascular Pneumonia positive Rash respiratory respiratory symptom respiratory symptoms Reticular dermis Ritonavir SARS-CoV-2 SARS-COV-2 infection Seven skin spongiosis swelling tested Tocilizumab transferred treated trunk upper limbs vascular abnormalities Viral with COVID-19
[DOI] 10.1186/s13000-021-01075-6 PMC 바로가기 [Article Type] Case Reports

Impact of intravenous lidocaine on clinical outcomes of patients with ARDS during COVID-19 pandemia (LidoCovid): A structured summary of a study protocol for a randomised controlled trial

COVID-19 대유행 중 ARDS 환자의 임상 결과에 대한 정맥내 리도카인의 영향(LidoCovid): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2021-02-112022-09-10
Journal: Trials [Category] MERS, 임상,

[키워드] 1:1 24 hour 24 hours acute renal failure acute respiratory distress acute respiratory distress syndrome Admission adverse event adverse events age albumin All participant All participants Anti-inflammatory effects approved aPTT ARDS Atrial fibrillation Bacterial Berlin Beta Bicarbonate biological sample biological samples blinded Blinding blockers blood count bolus bronchospasm cardiac rhythm Cardiogenic shock Care care providers Child bearing clinical Clinical data Clinical outcome clinical study collected Commission comparator complete blood count Complication computer-generated Concentration conducted Consumption control group cough COVID-19 COVID-19 pneumonia Covid-19 subgroup CRP D-dimers delirium diagnostic Disease progression disorders dissemination distribution Distribution ratio dosage Effect element ethics committee evaluate the effect evaluated Evolution experimental group extubation ferritin fibrinogen FiO2 followed by following form France French Gas exchange HCG Hospitalized hypnotics ICU IL-6 Ileus Impact incidence include inclusion criteria Inflammation Inflammatory marker inflammatory markers intensive care intensive care unit interval intervention group intravenous Intubated investigator LDH Length lidocaine Local local anaesthetics Local anesthetics Lymphocytes moderate moderate to severe Modification molecular mechanisms of pharmacological action Mortality NaCl number objective Older opioids outcome Pandemia PaO2 PaO2/FiO2 ratio parallel group participant Patient patients with ARDS PCT Phase 3 Placebo placebo-controlled Platelets Pneumonia pneumopathy Pneumothorax Prevent Primary outcome protection Protective protocol QTc random randomisation randomised randomised controlled trial randomize Randomized Randomly receive Recovery time recruitment Registered Renal Dialysis renal failure report respiratory distress RT-PCR Sample size SARS-CoV2 infection secondary endpoint Secondary endpoints sedated Severe acute respiratory syndrome severe ARDS Shock Social Security Social security system sore throat status Stratification stroke Study protocol supplementary material surgical syndrome tetraplegia thromboembolic Thromboembolic event timepoint Toxicity Treatment Trial Trial registration triglycerides troponin two group two groups university vasopressors Ventilation ventilator ventilator-free day Ventilator-free days website women written Informed Consent
[DOI] 10.1186/s13063-021-05095-x PMC 바로가기 [Article Type] Letter

Clinical characteristics and outcomes of critically ill COVID-19 patients in Tokyo: a single-center observational study from the first wave

도쿄의 중환자 COVID-19 환자의 임상 특성 및 결과: 첫 번째 물결의 단일 센터 관찰 연구

Observational Study

Published on 2021-02-092022-09-10
Journal: BMC Infectious Diseases [Category] MERS, 임상, 치료제,

[키워드] Admission age analyzed center characteristic Characteristics clinical Clinical course clinically coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critically ill Day death died discharged early phase elevated extracorporeal membrane oxygenation Favipiravir First wave High dose Hospital stay ICU In-hospital death Inflammatory intensive care intensive care unit Intubated investigated Japan Japanese Laboratory laboratory finding laboratory findings Laboratory-confirmed COVID-19 lymphocyte majority male marker mechanical ventilation median median age Methylprednisolone Mortality neutrophil Neutrophil-to-lymphocyte ratio observational study on admission one patient outcome oxygen oxygen supplementation pandemic Patient patients peaked receiving reflected Result retrospective single-center Steroids survival survivor Systemic steroid systemic steroids Tokyo tracheostomy trend two patients Ventilation ventilator was performed was used
[DOI] 10.1186/s12879-021-05840-2 PMC 바로가기 [Article Type] Observational Study