Ivermectin – Page 13 – Communicable Diseases Research

Attenuation of clinical and immunological outcomes during SARS‐CoV‐2 infection by ivermectin

이버멕틴에 의한 SARS-CoV-2 감염 중 임상 및 면역학적 결과의 약화

Article

Published on 2021-07-122022-09-11
Journal: EMBO Molecular Medicine [Category] MERS, SARS, 변종,

Key summary of German national treatment guidance for hospitalized COVID-19 patients Key pharmacologic recommendations from a national German living guideline using an Evidence to Decision Framework (last updated 17.05.2021)

Original Paper

Published on 2021-07-062022-10-29
Journal: Infection [Category] COVID-19, COVID19(2023년), MERS, SARS,

[키워드] added analyses Analysis anticoagulation bleeding Consensus Corticosteroid COVID-19 decision eight Evidence executive framework Guidance Hospitalized hospitalized COVID-19 patient hospitalized patient IL-6 antagonist Inpatient Interpretation Intervention Ivermectin Living guideline Living meta-analysis Meta-analysis National Patient plasma progressive disease Prophylactic recommendation Result risk risk factor routine care SARS-CoV-2 SARS-COV-2 infection selected Standard of care supplemental oxygen supported systematic review therapy Tocilizumab Treatment Venous Thromboembolism VTE WHO with COVID-19
[DOI] 10.1007/s15010-021-01645-2 PMC 바로가기 [Article Type] Original Paper

Pharmacological Treatment of Patients with Mild to Moderate COVID-19: A Comprehensive Review

Review

Published on 2021-07-052022-10-29
Journal: International Journal of Environmental Research an [Category] COVID-19, SARS,

The effect of cattle-administered ivermectin and fipronil on the mortality and fecundity of Anopheles arabiensis Patton

소에 투여된 이버멕틴과 피프로나일이 아노펠레스 아라비엔시스 패튼의 사망률과 생식력에 미치는 영향

Research

Published on 2021-07-022024-08-08
Journal: Parasites & Vectors [Category] 말라리아,

[키워드] Anopheles arabiensis cattle Endectocides Fipronil Ivermectin livestock malaria vector control
[DOI] 10.1186/s13071-021-04846-8 PMC 바로가기 [Article Type] Research

Ivermectin to prevent hospitalizations in patients with COVID-19 (IVERCOR-COVID19) a randomized, double-blind, placebo-controlled trial

Ivermectin Covid-19 환자 (Ivercor-Covid19)의 입원을 예방하기위한 Ivermectin 무작위, 이중 맹검, 위약 대조 시험

Randomized Controlled Trial

Published on 2021-07-022022-08-13
Journal: BMC Infectious Diseases [Category] 임상, 치료제,

[키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus age Arm Chain Reaction changed conducted coronavirus coronavirus disease COVID-19 determine Disease progression dose double-blind Efficacy End points evaluated events groups had no high-risk population Hospitalization hospitalizations Inclusion individual individuals with COVID-19 invasive invasive mechanical invasive mechanical ventilatory support invasive MVS Ivermectin ivermectin group ivermectin treatment limitation measure median time negativity no significant differences no significant effect objective Odds ratio outcome outcomes Patient patient’s weight patients patients with COVID-19 Placebo placebo group placebo-controlled study placebo-controlled trial polymerase chain polymerase chain reaction positive nasal swab Prevent prevent disease progression Primary outcome Randomized randomized, double-blind, placebo-controlled study required respiratory Result SARS-CoV-2 SARS-CoV2 Scientific community secondary outcome Secondary outcomes severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significant difference significant differences significant effect statistically statistically significant difference study enrollment supplementary material symptom onset telephone the median time Treatment Trial Trial registration ventilatory support
[DOI] 10.1186/s12879-021-06348-5 PMC 바로가기 [Article Type] Randomized Controlled Trial

Repurposing approved drugs as inhibitors of SARS-CoV-2 S-protein from molecular modeling and virtual screening

분자 모델링 및 가상 스크리닝으로부터 SARS-COV-2 S- 단백질의 억제제로 승인 된 약물을 재구성

Article

Published on 2021-07-012022-08-31
Journal: Journal of biomolecular structure & dynamics [Category] SARS, 신약개발, 치료제,

[키워드] angle approach approved drug approved drugs best binding energy calculated candidate Candidates clinical trial clinical trials complexes COVID-19 COVID-19 outbreak database disease docking domain drug drug design FDA approved Drugs Formula group human cell in vitro Infection inhibit inhibitors of SARS-CoV-2 Ivermectin library Ligand MD simulation MD simulations MM/PBSA molecular molecular dynamics Molecular modeling Novel coronavirus performed protein complexes RBD RBD region Receptor-binding domain Replication repurposing residues responsible S-protein SARS-CoV-2 SARS-CoV-2 virus selected solvate solvent spike Spike protein surface area target the SARS-CoV-2 transition Vaccine Viral viral replication Virtual screening water were used
[DOI] 10.1080/07391102.2020.1772885 PMC 바로가기 [Article Type] Article

Ivermectin and mortality in patients with COVID-19: A systematic review, meta-analysis, and meta-regression of randomized controlled trials

코로나19 환자의 이버멕틴과 사망률: 무작위 대조 시험의 체계적인 검토, 메타 분석 및 메타 회귀

Meta-Analysis

Published on 2021-07-012022-09-11
Journal: Diabetes & metabolic syndrome [Category] SARS, 신약개발, 임상,

[키워드] age Analysis benefit certainty of evidence ClinicalTrials control group coronavirus COVID-19 database databases decreased mortality diabete diabetes double-blinded hypertension inception intervention group Ivermectin Meta-analysis meta-regression Mortality Patient patients with COVID-19 Placebo placebo-controlled Primary outcome Randomized controlled trial RCT RCTs reduction reported required risk risk ratio SARS-CoV-2 sensitivity analysis severe COVID-19 Sex Standard of care statistical significance subgroup analysis systematic literature search systematic review therapy was performed was reduced
[DOI] 10.1016/j.dsx.2021.102186 PMC 바로가기 [Article Type] Meta-Analysis

Environmental impact assessment of COVID-19 therapeutic solutions. A prospective analysis

Research article

Published on 2021-07-012022-10-05
Journal: The Science of the total environment [Category] SARS, 치료제,

Niosomal versus nano-crystalline ivermectin against different stages of Trichinella spiralis infection in mice

Article

Published on 2021-07-012023-06-22
Journal: Parasitology research [Category] 조류인플루엔자,

[키워드] Angiogenesis Inflammation Ivermectin Mallory stains Niosomes oxidative stress trichinellosis
[DOI] 10.1007/s00436-021-07172-1

Self-prescribed Ivermectin use is associated with a lower rate of seroconversion in health care workers diagnosed with COVID, in a dose-dependent response

자가 처방 Ivermectin 사용은 용량 의존적 반응에서 COVID로 진단된 의료 종사자의 낮은 혈청 전환율과 관련이 있습니다

Article

Published on 2021-07-012022-09-11
Journal: The Brazilian journal of infectious diseases : an [Category] SARS, 진단, 치료기술,

[키워드] abdominal pain age antibody Brazil Clinical efficacy Cohort consequence COVID COVID-19 cross-sectional cross-sectional study cytokine Cytokines diagnosed diagnosed with COVID-19 diarrhea disease severity dose dose-dependent drug Effectiveness evaluate the effect evaluated Evidence groups HCW Health care Health care worker health care workers immune response immunomodulatory effects Impact impairment in vitro increasingly Ivermectin lack less mechanism mononuclear cell mononuclear cells multiple dose multiple doses Neutralizing antibodies neutralizing antibody Pain participant Patient PBMC PBMCs performed Peripheral blood Peripheral blood mononuclear cells Professor purified rate of seroconversion Reinfection reported risk SARS-CoV-2 SARS-CoV-2 treatment Seroconversion Side-effect Spike protein stimulated stratified Treatment treatment of COVID-19 women
[DOI] 10.1016/j.bjid.2021.101603 PMC 바로가기 [Article Type] Article