Genetic Mapping of Specific Interactions between Aedes aegypti Mosquitoes and Dengue Viruses이집트숲모기(Aedes aegypti Mosquitoes)와 뎅기열 바이러스(Dengue Viruses) 간의 특정 상호작용의 유전적 매핑Research Article Published on 2013-08-012022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Aede assigned Author contribute correlation Critical Defense defense mechanisms Dengue dengue virus dengue viruses detected determine discriminatory power explained Factor Factors G×G interaction G×G interactions Genetic genetic architecture genetic factors genetic loci genetic mapping Genome Genotype Health Host host-pathogen interaction immune responses Interaction interactions invertebrate invertebrates isolate loci mapped mapping marker mechanism mechanisms molecular mechanism molecular mechanisms Mosquito mosquito-virus natural population outcome pathogen pathogen genotype pathogen genotypes Pathogens Patient patients phenotype phenotypic phenotypic variation physical Region remained serotype significantly Specific specificity the mosquito Variation vector virus virus isolate viruses [DOI] 10.1371/journal.pgen.1003621 PMC 바로가기 [Article Type] Research Article
Genome-Wide Association Mapping in Dogs Enables Identification of the Homeobox Gene, NKX2-8 , as a Genetic Component of Neural Tube Defects in Humans개의 게놈 전반에 걸친 연관 매핑을 통해 인간의 신경관 결함의 유전적 구성 요소인 호메오박스 유전자 NKX2-8 식별 가능Research Article Published on 2013-07-182022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] addition affected Analysis animal animal models Author birth defects Brain canine Care caused Central nervous system chromosome closure codon Combination comparable complex component condition contribute costly defect develop disease dog during pregnancy dysraphism embryonic ENCODE environmental factors etiology Evidence ExoN exons expected explain expressed failure found frameshift frameshift mutation general term Genes Genetic Genetic studies genetics Genome genome-wide association genomic region home environment Homeobox Human human population human populations humans identification identify in addition to interactions lead malformation mapped mapping mechanism Medical care molecular basis morbidity and mortality multifactorial Mutation Neural neural tube Neural tube defect Neural tube defects NKX2 NKX2-8 NTD NTDs occur pathology Patient performed predicted Pregnancy premature stop codon Protein rare variant Rare variants receive Regulatory regulatory gene reported resulting secondary to sequenced Sequencing significantly skin Soft tissue spina bifida spinal cord spinal dysraphism Structure Taking tissue tissues tube vertebral column Weimaraner [DOI] 10.1371/journal.pgen.1003646 PMC 바로가기 [Article Type] Research Article
Mapping of PARK2 and PACRG Overlapping Regulatory Region Reveals LD Structure and Functional Variants in Association with Leprosy in Unrelated Indian Population GroupsPARK2 및 PACRG 겹치는 규제 영역의 매핑은 관련 없는 인도 인구 그룹의 나병과 관련된 LD 구조 및 기능적 변이를 나타냅니다.Research Article Published on 2013-07-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 한센병, [키워드] a major Affect assay association Author caused China clinical forms compared declined different disease disease pathogenesis Frequency Gene Gene Expression genetic background Genome genomic region granulomatous infection groups health problem heterogeneity Host human gene human genes impairment India Infection Infectious disease leprosy mapping Mycobacterium Mycobacterium leprae North organism other variant other variants PACRG Pathogenesis peripheral nerves Population population group population groups populations Prevalence provide public health reason for Region regulatory region replicated Replication reported reporter saturated several gene several genes significantly skin SNP SNPs Structure structures susceptibility the disease therapy upstream [DOI] 10.1371/journal.pgen.1003578 PMC 바로가기 [Article Type] Research Article
Mapping Environmental Suitability for Malaria Transmission, Greece말라리아 전파를 위한 환경 적합성 매핑, 그리스Dispatch Published on 2013-05-012024-08-13 Journal: Emerging Infectious Diseases [Category] 말라리아, [키워드] Greece Infectious diseases malaria mapping parasites Transmission vector-borne infections [DOI] 10.3201/eid1905.120811 PMC 바로가기 [Article Type] Dispatch
A high-resolution geospatial surveillance-response system for malaria elimination in Solomon Islands and Vanuatu솔로몬 제도와 바누아투에서 말라리아 제거를 위한 고해상도 지리공간 감시-대응 시스템Research Published on 2013-03-212024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Geographic Information Systems (GIS) Malaria elimination mapping Spatial decision support systems (SDSS) Surveillance [DOI] 10.1186/1475-2875-12-108 PMC 바로가기 [Article Type] Research
The effects of urbanization on global Plasmodium vivax malaria transmission도시화가 전 세계 말라리아 원인균인 플라스모디움 비박스 전파에 미치는 영향Research Published on 2012-12-052024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Dominant Anopheles vectors mapping Plasmodium vivax urbanization [DOI] 10.1186/1475-2875-11-403 PMC 바로가기 [Article Type] Research
The WWARN Antimalarial Quality SurveyorWWARN 항말라리아 품질 조사기Article Published on 2012-05-012024-08-14 Journal: Pathogens and Global Health [Category] 말라리아, [키워드] Falsified malaria mapping Medicines substandard [DOI] 10.1179/204777312X13419245939520 PMC 바로가기
The SARS Coronavirus S Glycoprotein Receptor Binding Domain: Fine Mapping and Functional CharacterizationResearch Published on 2005-08-252022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] ACE2 Alanine amino acid residue appear binding binding energy Cell characterization characterized cloned contribute decrease determined eight expressed expression functional Glutamine glycoprotein glycosylation glycosylation site identify immune responses include indicate initiated kDa lack Li mapping mechanism molecular weight Mutagenesis mutated Mutation not affect R426 RBD receptor receptor ACE2 reduced required residue residues S RBD SARS Coronavirus significantly Simultaneous submitted suggested the RBD the receptor-binding domain These data [DOI] 10.1186/1743-422X-2-73 PMC 바로가기 [Article Type] Research