MERS-CoV – Page 13 – Communicable Diseases Research

Computational Modeling of T Cell Hypersensitivity during Coronavirus Infections Leading to Autoimmunity and Lethality

자가 면역 및 치사율로 이어지는 코로나바이러스 감염 중 T 세포 과민증의 전산 모델링

Article

Published on 2022-03-222022-09-11
Journal: Computational and Mathematical Methods in Medicine [Category] SARS, 변종,

[키워드] Analysis angiotensin antiviral drug Autoimmune response autoimmune responses Autoimmunity binding CD147 COVID-19 COVID-19 treatment Critical Delta determinant determinants develop docking domain hACE2 human Angiotensin-converting enzyme Hyperactivation implication in silico indicated individuals infected with SARS-CoV-2 Interaction investigated involved isoform leading lethality memory T cell memory T cells MERS MERS-CoV modeling molecular molecular docking molecular dynamics not affect omicron Omicron variants outcome outcomes Patient performed polar interaction polar interactions Protein binding provide receptor receptors residue resulting SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein severe COVID-19 shown Spike protein suggested T cell T cells the SARS-CoV-2 transmembrane glycoprotein Treatment variants of SARS-CoV-2 viral spike protein
[DOI] 10.1155/2022/9444502 PMC 바로가기 [Article Type] Article

From delta to Omicron: S1-RBD/S2 mutation/deletion equilibrium in SARS-CoV-2 defined variants

델타에서 오미크론으로: SARS-CoV-2 정의된 변이체에서 S1-RBD/S2 돌연변이/결실 평형

Review

Published on 2022-03-102022-09-11
Journal: Gene [Category] MERS, SARS, 변종, 유전자 메커니즘, 진단,

Targeting the Interaction Between Spike Protein and Nucleocapsid Protein for Suppression and Detection of Human Coronavirus OC43

인간 코로나바이러스 OC43의 억제 및 검출을 위한 스파이크 단백질과 뉴클레오캡시드 단백질 간의 상호작용 표적화

Article

Published on 2022-03-102022-09-11
Journal: Frontiers in Immunology [Category] SARS, 변종, 치료기술, 치료법, 치료제,

[키워드] anti-HCoV-OC43 anti-HCoV-OC43 N antibody bait and prey C-terminal domain Cell colds conserved coronavirus detect detection ELISA fusion protein HCoV HCoV-OC43 Human human coronavirus human coronavirus OC43 in vitro Infection inhibit interact Interaction investigated MERS MERS-CoV monoclonal antibody N protein N proteins Novel coronavirus nucleocapsid nucleocapsid protein OC43 Penetrating peptide prey producing Protein protein expression Replication replication of SARS-CoV-2 reported S protein SARS-CoV-2 spike Spike protein suppression target targeting the S protein Therapeutics upper respiratory tract variants virus virus detection
[DOI] 10.3389/fimmu.2022.835333 PMC 바로가기 [Article Type] Article

Comparative analysis of alignment-free genome clustering and whole genome alignment-based phylogenomic relationship of coronaviruses

Research Article

Published on 2022-03-082022-10-28
Journal: PLoS ONE [Category] COVID-19, SARS,

Escape and Over-Activation of Innate Immune Responses by SARS-CoV-2: Two Faces of a Coin

SARS-CoV-2에 의한 타고난 면역 반응의 탈출 및 과잉 활성화: 동전의 두 얼굴

Review

Published on 2022-03-042022-09-11
Journal: Viruses [Category] Coronavirus, SARS, 유전자 메커니즘,

[키워드] addition cellular receptor coin coronavirus CoV COVID-19 pathogenesis CoVs Cytokines Defense disease dysregulated escape evade face Host human population IFN IFN signaling pathways IL-1 IL-1 family cytokine IL-1 family cytokines IL-18 IL-1β immune responses Inflammasome inflammasome activation inflammasomes Innate innate immune innate immune response innate immune responses innate immune system Innate immunity interferon invading pathogens MERS MERS-CoV Multiple Pathogenesis Pathogens potential mechanism potential mechanisms Prognosis pyroptosis Recognition response SARS-CoV-1 SARS-CoV-2 with COVID-19
[DOI] 10.3390/v14030530 PMC 바로가기 [Article Type] Review

Drug repurposing for SARS-CoV-2 main protease: Molecular docking and molecular dynamics investigations

Research article

Published on 2022-03-012022-10-05
Journal: Biochemistry and Biophysics Reports [Category] 신약개발,

Developing pan-β-coronavirus vaccines against emerging SARS-CoV-2 variants of concern

우려되는 신종 SARS-CoV-2 변이체에 대한 범-β-코로나바이러스 백신 개발

Article

Published on 2022-03-012022-09-11
Journal: Trends in immunology [Category] SARS, 변종, 비임상,

CD4 + T cells from COVID-19 mRNA vaccine recipients recognize a conserved epitope present in diverse coronaviruses

Clinical Trial

Published on 2022-03-012022-10-04
Journal: The Journal of Clinical Investigation [Category] MERS, SARS, 임상,

Polysaccharides and Their Derivatives as Potential Antiviral Molecules

Review

Published on 2022-02-182022-10-28
Journal: Viruses [Category] COVID-19, COVID19(2023년), Fulltext, SARS,

Classical and Next-Generation Vaccine Platforms to SARS-CoV-2: Biotechnological Strategies and Genomic Variants

SARS-CoV-2에 대한 고전 및 차세대 백신 플랫폼: 생명공학 전략 및 게놈 변이

Review

Published on 2022-02-182022-09-10
Journal: International Journal of Environmental Research an [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘,

[키워드] aAPC Ad5-nCoV adaptive Amino acid amino acids animals antibody applied B.1.1.7 B1.351 BBIBP-CorV bind Biotechnology BNT Cell classical clinical trial consequence CoronaVac coronavirus COVID-19 COVID-19 vaccine COVID-19 vaccines CoVs D614G Deletion demonstrated dendritic cell dendritic cells domain escape Evolution genomic variant genomic variants HCoV HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 high affinity HKU1 hosts Human humans inactivated incorporation inhibit INO-4800 JNJ-78436735 lentiviral Lentiviral vector LV-SMENP-DC MERS-CoV molecular mRNA mRNA-1273 mutated nCoV New new SARS-CoV-2 new strain NL63 NVX-CoV2373 vaccine P.1 pathogen Pathogens platform Protein RBD receptor ACE2 Receptor-binding domain recombinant vaccine recombinant vaccines replacement residue responsible RNA vaccines S protein SARS-CoV SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 variants strain Strains Strategy subunits technological platforms tested the S protein Transmissibility trials Vaccine vaccine production Vaccines variant variants variety Viral virus-like particles β-coronavirus β-CoV β-CoVs
[DOI] 10.3390/ijerph19042392 PMC 바로가기 [Article Type] Review