Natural language processing of radiology reports to investigate the effects of the COVID-19 pandemic on the incidence and age distribution of fracturesCOVID-19 대유행이 골절의 발병률 및 연령 분포에 미치는 영향을 조사하기 위한 방사선 보고서의 자연어 처리Scientific Article Published on 2021-04-132022-09-10 Journal: Skeletal Radiology [Category] COVID19(2023년), Fulltext, MERS, SARS, 치료기술, [키워드] age Analysis automated automatically average can be used changes in children COVID-19 pandemic distribution Effect elbow emergency condition F 1 score Fracture fractures hospital identify incidence material natural language natural language processing objective pandemic Pathologies pathology Patient presenting Radiographs radiological Radiological reports radiology Real-time monitoring reported Result shown significant decrease significantly significantly lower Trigger use case [DOI] 10.1007/s00256-021-03760-5 PMC 바로가기 [Article Type] Scientific Article
Is butyrate a natural alternative to dexamethasone in the management of CoVID-19?Review Published on 2021-04-062022-10-31 Journal: F1000Research [Category] COVID-19, SARS, [키워드] acute respiratory distress affected anti-inflammatory effect anti-inflammatory properties Butyrate butyric acid caused coronavirus 2 Coronavirus disease 2019 Corticosteroid COVID-19 Critical Cytokine storm death Deleterious Dexamethasone effective fatty Fatty acid gut microbiota hyperinflammation immune response Infection management Micronutrient oxidative stress Pathologies patients Probiotics produced reduce reduction respiratory respiratory viral infections Serious Adverse Event shown syndrome the cytokine storm the gut-lung axis the patient use of corticosteroid [DOI] 10.12688/f1000research.51786.1 PMC 바로가기 [Article Type] Review
Network Meta-Analysis on the Mechanisms Underlying Alcohol Augmentation of COVID-19 PathologiesCOVID-19 병리의 알코올 증강의 기본 메커니즘에 대한 네트워크 메타 분석Meta-Analysis Published on 2021-04-012022-08-31 Journal: Alcoholism, clinical and experimental research [Category] MERS, meta-analysis, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect affected alcohol alcohol consumption Analysis anti-inflammatory mediator anti-inflammatory mediators augmentation base bioRxiv caused cellular metabolism changes in clinician conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients cytokine Cytokines dataset early phase Effect ENhance Ethanol EtOH Fever fibrosis Gene Expression gene expression profile GEO GEO database glucocorticoid Glucocorticoid receptor hepatic fibrosis HMGB1 homeostasis hyperinflammatory phase IL-1 IL-1β IL-6 IL-6 signaling pathways Inflammation Inflammatory mediators Ingenuity Pathway Analysis Ingenuity Pathway Analysis. inhibiting IPA JUN knowledge base lung mapped mediators Meta-analysis metabolism molecule molecules network Network meta-analysis Neuroinflammation pandemic Pathologies pathway Pathways Patient predicted receptor respiratory retrieved risk RNA-sequencing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 proteins sequencing data severe acute respiratory syndrome Coronavirus signaling pathway STAT systemic inflammation TNF transcription factors Viral viral infections worldwide crisis [DOI] 10.1111/acer.14573 PMC 바로가기 [Article Type] Meta-Analysis
[Impact of COVID-19 on the presentation and course of acute appendicitis in paediatrics]Observational Study Published on 2021-04-012022-10-05 Journal: Anales de pediatria [Category] 임상, [키워드] Acute appendicitis age Apendicitis aguda Apendicitis complicada Appendicitis Care children clinical complication Complicaciones postoperatorias Complicated appendicitis complications Course COVID-19 COVID-19 pandemic decrease diagnosed Diagnosis English Health Hospitalization increase in intraoperative material Observational cohort study Pandemia pandemic Pathologies Patient Perforación Perforation postoperative Postoperative Complications severity significant difference Spanish surgical pathology the disease [DOI] 10.1016/j.anpedi.2020.12.003 PMC 바로가기 [Article Type] Observational Study
Amino acid sensing pathway: A major check point in the pathogenesis of obesity and COVID-19아미노산 감지 경로: 비만과 코로나19 발병의 주요 체크포인트Review Published on 2021-04-012022-09-11 Journal: Obesity Reviews [Category] SARS, 유전자 메커니즘, [키워드] Activation aggravate Amino acid amino acid sensor GCN2 amino acids antiviral response Comorbidities Comorbidity correlation COVID-19 COVID-19 susceptibility deficiency effective GCN2 Host host cell host cells Hyperactivation IL-1β increase Infection Inflammation inhibiting interleukin interleukin-1 beta intestinal inflammation mammalian mechanism mitigate Mortality mTOR obesity obesogenic opposite overnutrition oxygen Pathogenesis Pathologies pathway pro-inflammatory cytokine Rapamycin reactive oxygen species reactive oxygen specy Replication reprogramming ROS SARS-CoV-2 serum shown suppresse susceptibility translation translational viral infections Viremia while with COVID-19 [DOI] 10.1111/obr.13221 PMC 바로가기 [Article Type] Review
Transcriptional and Non-Transcriptional Activation, Posttranslational Modifications, and Antiviral Functions of Interferon Regulatory Factor 3 and Viral Antagonism by the SARS-CoronavirusSARS-Coronavirus에 의한 Interferon Regulatory Factor 3과 Viral Antagonism의 전사 및 비전사 활성화, 번역 후 변형, 항바이러스 기능Review Published on 2021-03-292022-09-10 Journal: Viruses [Category] SARS, 유전자 메커니즘, [키워드] absence activated Activation addition antagonism Antiviral Apoptosis cause cellular concert coronavirus Critical defend demonstrated dual enzyme Factor function functions Host IFNβ immune responses immune system infected cells Infection inhibit innate antiviral immunity innate immune innate immune responses interferon interferon regulatory factor interferon-stimulated gene interferon-stimulated genes invading pathogen invading pathogens IRF3 ISGs limit mechanism mice Pathogens Pathologies pathway posttranslational modification posttranslational modifications protective immunity protein stability PTMs regulate Regulatory responsible restrict RIPA SARS-CoV-2 signaling pathways Stage susceptibility therapy this system transcription factor transcriptional transcriptional activity Trigger Viral viral antagonism viral infections Viral protein Viral proteins virus virus infection virus replication virus spread virus-infected cells viruses [DOI] 10.3390/v13040575 PMC 바로가기 [Article Type] Review
Using artificial intelligence to improve COVID-19 rapid diagnostic test result interpretation인공 지능을 사용하여 COVID-19 신속한 진단 테스트 결과 해석 개선422 Published on 2021-03-232022-09-12 Journal: Proceedings of the National Academy of Sciences of [Category] SARS, 진단, [키워드] Classifier clinician color confidence COVID-19 COVID-19 pandemic creating evaluated IMPROVE Interpretation Laboratory machine learning Pathologies Patient positive Precision Rapid diagnostic test RDT RDTs reduce SARS-CoV-2 serological smartphone application [DOI] 10.1073/pnas.2019893118 PMC 바로가기 [Article Type] 422
Evolution of Pathology Patterns in Persons Who Died From COVID-19 in Italy: A National Study Based on Death CertificatesMedicine Published on 2021-03-222022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] age Care cause of death Certificate changed circulation coded Comorbidities Comorbidity complex Complication coronavirus disease COVID-19 death death certificate Deceased defined determine diabete Diagnosis died disease epidemic wave Factor Frequency health system hospitals hypertensive ICD individual ischemic heart disease Italy knowledge less Mortality much lower neoplasm Older Pathologies Patient patients patients with COVID-19 pattern Person Pneumonia positive protocol provided reached reduction Respiratory failure resulting SARS-CoV-2 significantly higher Surveillance survival tested the epidemic Treatment virus [DOI] 10.3389/fmed.2021.645543 PMC 바로가기 [Article Type] Medicine
Developing therapeutic approaches for twenty-first-century emerging infectious viral diseases Reviews Published on 2021-03-152022-10-05 Journal: Nature Medicine [Category] SARS, 신약개발, 유전자 메커니즘, 진단, 치료제, [키워드] accelerate antibody Antiviral approach approved combination therapy coronavirus disease COVID-19 develop Developing Direct-acting antivirals disease drug drug resistance drugs Effectiveness effort Epidemic events expected Immune-mediated offer outbreak Outbreaks pandemic pandemic virus Pandemics Pathologies Population recorded reduce Research Therapeutic approach therapeutic potential therapeutic window These data viral disease virus while [DOI] 10.1038/s41591-021-01282-0 [Article Type] Reviews
Taking a step down on the reconstruction ladder for head and neck reconstruction during the COVID-19 pandemicResearch Article Published on 2021-03-082022-10-28 Journal: BMC Surgery [Category] COVID-19, [키워드] age approach benefit Cancer Combination COVID-19 pandemic defect females flap Follow-up HCW Head and neck reconstruction Health health system involved male metal MOST Mucormycosis mucosa myocutaneous flap Pathologies Patient patients pectoralis Pedicled flaps in free flap era PPE protocols Reconstruction in COVID 19 pandemic Region Result Squamous cell carcinoma surgical survived Taking tongue Treatment unique was done was used [DOI] 10.1186/s12893-021-01134-1 PMC 바로가기 [Article Type] Research Article