Impact of High-Dose Prophylactic Anticoagulation in Critically Ill Patients With COVID-19 PneumoniaObservational Study Published on 2021-06-012022-10-05 Journal: Chest [Category] 임상, [키워드] 95% CI accounted Anticoagulant anticoagulant therapy anticoagulation bleeding clinical collected consecutive patient Controlled trial COVID-19 Critically ill patient defined dose eight favor French hazard ratio hemorrhage hemorrhagic events high risk High-dose ICU ICU admission Ill Impact incidence increased risk laboratory data Patient Probability Prophylactic Prophylaxis Pulmonary embolism recorded reduced risk reduction in risk SARS-COV-2 infection standardized protocol therapeutic thrombosis thrombotic thrombotic complication Treatment with COVID-19 [DOI] 10.1016/j.chest.2021.01.017 PMC 바로가기 [Article Type] Observational Study
COVID-19 Era Social Isolation among Older AdultsReview Published on 2021-05-182022-10-31 Journal: Geriatrics [Category] COVID-19, [키워드] Adults approach common conducted connection consequence Consequences COVID-19 Critical database greater Health highlight identify Impact indicate Isolation literature review measure Older Older adults pandemic Prevent protocol reduced risk released Research resource Safety social connectedness social distancing social isolation social recession virus website while worsened [DOI] 10.3390/geriatrics6020052 PMC 바로가기 [Article Type] Review
Systematic review and meta-analysis of tocilizumab in persons with coronavirus disease-2019 (COVID-19)코로나바이러스 감염증-2019(COVID-19) 환자에 대한 토실리주맙의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-05-172022-09-12 Journal: Leukemia [Category] MERS, SARS, 임상, 진단, [키워드] 2019-nCoV 95% confidence interval Analysis Boolean operator Boolean operators Cohort Cohort studies cohort study Control coronavirus coronavirus disease coronavirus disease-2019 COVID-19 death determine discharged Efficacy Endpoint Hospitalization ICU admission Immunotherapy Infectious diseases Invasive mechanical ventilation Jadad scale Meta-analysis not decreased performed question Randomized randomized trial reduced risk relative Relative risk review risk of death SARS-CoV-2 searched Secondary infection secondary infections subject Tocilizumab was used Web of Science with COVID-19 [DOI] 10.1038/s41375-021-01264-8 PMC 바로가기 [Article Type] Meta-Analysis
Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines on covid-19 related symptoms, hospital admissions, and mortality in older adults in England: test negative case-control study화이자-바이오엔텍 및 옥스포드-아스트라제네카 백신이 영국 노인의 코로나19 관련 증상, 입원 및 사망률에 미치는 효과: 음성 사례 대조 연구 테스트Observational Study Published on 2021-05-132022-09-11 Journal: The BMJ [Category] Fulltext, SARS, 변종, 임상, [키워드] 95% confidence interval Admission Admissions Adults B.1.1.7 B.1.1.7 variant baseline BNT162b2 case-control study ChAdOx1 ChAdOx1-S Chain Reaction Combined commenced COVID-19 symptoms death deaths dose duration of follow-up Effect effective Effectiveness Effects England higher odd higher odds hospital Hospital admission Hospital admissions immunisation individuals Mortality nine Odds ratio of BNT162b2 Older outcome Oxford-AstraZeneca participant Pfizer-BioNTech polymerase chain polymerase chain reaction positive Primary outcomes protection reached reduced risk reduction in reported symptom risk risk of infection SARS-CoV-2 infections second dose severe disease single dose Symptom symptomatic symptomatic COVID-19 symptomatic disease Symptoms System Test test negative the vaccine vaccination Vaccine variant [DOI] 10.1136/bmj.n1088 PMC 바로가기 [Article Type] Observational Study
Impact of in-hospital discontinuation with angiotensin receptor blockers or converting enzyme inhibitors on mortality of COVID-19 patients: a retrospective cohort studyCOVID-19 환자의 사망률에 대한 지오텐신 수용체 차단제 또는 전환 효소 억제제의 병원 내 중단의 영향: 후향적 코호트 연구Research Article Published on 2021-05-122022-09-10 Journal: BMC Medicine [Category] SARS, 치료제, [키워드] 95%CI ACEi ACEi/ARB ACEIs adjusted Admission Adult patient Analysis angiotensin angiotensin receptor blocker Angiotensin receptor blockers angiotensin-converting enzyme inhibitor angiotensin-converting enzyme inhibitors ARB ARBs carried Cohort cohorts conditions contrary COVID-19 COVID-19 pandemic Cox regression model death diabete diabetes discharge drug enzyme First wave hazard ratio hazard ratios head Head-to-head comparison heart failure High-risk patients hospital hospitals HRs Hypothesis Impact IMPROVE In-hospital In-hospital death in-hospital mortality in-hospital mortality rate in-hospital mortality rates In-hospital treatment increased the risk inhibitor intention-to-treat male mediators Mortality mortality rate mortality risk no difference obesity Older Patient patients with obesity PCR-confirmed PCR-confirmed diagnosis propensity scores Receptor Blockers reduced reduced risk Renin-angiotensin system inhibitors Result retrospective cohort study selected severity significantly lower Spain Spread subject supplementary material survival survival analysis the disease treat Treatment [DOI] 10.1186/s12916-021-01992-9 PMC 바로가기 [Article Type] Research Article
Association of Calcitriol Supplementation with Reduced COVID-19 Mortality in Patients with Chronic Kidney Disease: A Population-Based StudyArticle Published on 2021-05-052022-10-28 Journal: Biomedicines [Category] COVID-19, [키워드] acute lung injury addition analyzed association benefit calcitriol chronic Chronic kidney disease controls COVID-19 COVID-19 mortality COVID-19 pandemic COVID-19 severity dose Effect experimental model individual Mortality multivariable outcome Patient reduced reduced risk renal function risk SARS-CoV2 infection severe COVID-19 shown treated patients Treatment variable Vitamin D [DOI] 10.3390/biomedicines9050509 PMC 바로가기 [Article Type] Article
Common variants at 21q22.3 locus influence MX1 and TMPRSS2 gene expression and susceptibility to severe COVID-19Research article Published on 2021-04-232022-10-05 Journal: iScience [Category] 유전자 메커니즘, [키워드] advanced age association Blood chromosome 21 clinical presentation Common variant Comorbidities Control coronavirus disease correlated COVID-19 disease European explain expression Factor FIVE Gene Expression Genetic genetic analysis genetic factor genetics Genome-wide association study Genomics Hospitalized Host host antiviral response implicated individual initiative locus Male sex Manifestations minor allele MX1 Pathogenesis performed potential therapeutic target reduced risk risk factor severe COVID-19 Single nucleotide polymorphism SNPs susceptibility TMPRSS2 [DOI] 10.1016/j.isci.2021.102322 [Article Type] Research article
Effects of Regular Physical Activity on the Immune System, Vaccination and Risk of Community-Acquired Infectious Disease in the General Population: Systematic Review and Meta-AnalysisSystematic Review Published on 2021-04-202022-10-28 Journal: Sports Medicine (Auckland, N.z.) [Category] Coronavirus, MERS, SARS, [키워드] 95% CI activity antibody association CD4 cell cell count CINAHL clinically Cochrane Central Cochrane guideline Concentration conducted controls COVID-19 database diagnosed Diseases Effect ENhance Evidence examined group hazard ratio hospitalisation IgA immune immune response immune system Immunoglobulin increase individuals infections Infectious disease Intervention mean difference Meta-analysis moderate Mortality neutrophil count Non-communicable disease objective parameters physical activity prospective observational study protocol PsycINFO Quantitative random-effects model randomised controlled trial reduced risk Registered Regular reported Resilience Result review risk risk reduction salivary searched selected Seven supplementary material System Systemic review vaccination Web of Science were excluded [DOI] 10.1007/s40279-021-01466-1 PMC 바로가기 [Article Type] Systematic Review
Women’s Depressive Symptoms during the COVID-19 Pandemic: The Role of PregnancyArticle Published on 2021-04-182022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] age Anxiety children Complete COVID-19 Depression depressive symptom determine Effect ENhance events experiment Factor Future Health healthy identify Increased less media mental health mother Obstetric offspring pandemic positive Pregnancy pregnant pregnant women Questionnaires recruited reduced risk reported Resilience risk risk factor role Stress Stress Scale Support susceptibility women [DOI] 10.3390/ijerph18084298 PMC 바로가기 [Article Type] Article
Personal protective equipment for reducing the risk of COVID-19 infection among health care workers involved in emergency trauma surgery during the pandemic: An umbrella reviewReview Article Published on 2021-04-122022-10-30 Journal: The journal of trauma and acute care surgery [Category] COVID-19, MERS, SARS, [키워드] adhere approach Assessing assessment automated broad evidence synthesis Canada Care conducted Contagion Controlled country COVID-19 criteria decontamination development Effect effective Efficacy ENhance equipment Evidence evidence-based practice eye feasible global health Health health care facility Health care worker health care workers hydrogen peroxide Infection involved Mask Masks measure moderate N95 masks N95 respirator not affect observational study overcome patients Personal protective equipment platform PPE Prospective Protective Quality recommendations reduce reduced risk reducing reduction in Registered reported resources Respirator reuse review risk risk of COVID-19 surgical trauma Trauma surgery ultraviolet Umbrella review [DOI] 10.1097/TA.0000000000003073 PMC 바로가기 [Article Type] Review Article