Immune Response in Myocardial Injury: In Situ Hybridization and Immunohistochemistry Techniques for SARS-CoV-2 Detection in COVID-19 AutopsiesMolecular Biosciences Published on 2021-10-262022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] Activation acute respiratory syndrome aggregate Autopsy cardiac ischemia caused CD4 CD8 cellular distribution changes in Combination component contribute coronavirus COVID-19 COVID-19 case cytokine detection disease FFPE histological hybridization ICU IFNγ IHC immune Inflammation Injury intensive care lung molecular morbidity and mortality multiplex Myocardium naïve nucleocapsid protein other organ Patient patients PCR PCR-positive performed Platelet positive Post-mortem Protein response S-protein SARS-CoV-2 SARS-CoV-2 qRT-PCR selected serology specimens spike Support T cells technique tissue vessel viral infection while widespread [DOI] 10.3389/fmolb.2021.658932 PMC 바로가기 [Article Type] Molecular Biosciences
In-Depth Longitudinal Comparison of Clinical Specimens to Detect SARS-CoV-2Article Published on 2021-10-212022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] asked clinical clinical symptom collected Complete coronavirus disease COVID-19 COVID-19 pandemic COVID-19 testing Diagnosis exhibited first positive gold standard highest Isolation longitudinal longitudinal analysis nasopharyngeal sample Nasopharyngeal swab Nasopharyngeal swab specimens nasopharynx Oropharyngeal oropharyngeal swabs participant Patient PCR test percentage persist persistence positive questionnaire rectal rectal specimen repeated Saliva sampling SARS-CoV-2 sensitivity specimen specimens Swab swabs symptom duration symptom onset tested Throat [DOI] 10.3390/pathogens10111362 PMC 바로가기 [Article Type] Article
Respiratory Pathogen Coinfections in SARS-CoV-2-Positive Patients in Southeastern Wisconsin: A Retrospective Analysis위스콘신 남동부의 SARS-CoV-2-양성 환자의 호흡기 병원체 동시 감염: 후향적 분석Research Article Published on 2021-10-202022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Adenovirus all age group all age groups analyzed children Coinfection coinfections collected coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Diagnosis disease severity enterovirus etiological agent female health authorities hosts human metapneumovirus impacted IMPROVE include Infection Influenza influenza A influenza B laboratory-confirmed male median age métapneumovirus nucleic acid pathogen Pathogens Patient polymicrobial infection polymicrobial infections Population positive Prognosis public health public health authorities public health authority respiratory respiratory pathogen respiratory pathogen panel respiratory virus respiratory viruses Retrospective analysis Retrospective study returned rhinovirus risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 patient SARS-CoV-2 patients SARS-CoV-2-positive patient SARS-CoV-2-positive patients severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specimen specimens Surveillance susceptible susceptible hosts tested Treatment viruses were used with COVID-19 [DOI] 10.1128/Spectrum.00831-21 PMC 바로가기 [Article Type] Research Article
Asymptomatic COVID-19 Adult Outpatients identified as Significant Viable SARS-CoV-2 Shedders무증상 COVID-19 성인 외래환자, 생존 가능한 SARS-CoV-2 셰더로 확인Article Published on 2021-10-182022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 치료기술, [키워드] adult outpatient Asymptomatic Cell culture Clinical management COVID-19 Ct values epidemiological French Health Infection infection control Infectious diseases measure median value occupational health Outpatient populations positive Quantitative recommendation respiratory RNA RNA load RNA loads RT-PCR assay SARS-CoV-2 SARS-CoV-2 RNA detection Significant significantly higher specimens subject symptomatic Transmission upper respiratory tract Viable Viral Viral load [DOI] 10.1038/s41598-021-00142-8 PMC 바로가기 [Article Type] Article
Concordance between PCR-based extraction-free saliva and nasopharyngeal swabs for SARS-CoV-2 testingResearch Article Published on 2021-10-152022-10-31 Journal: HRB Open Research [Category] COVID-19, [키워드] 95% CI Accuracy acute respiratory syndrome analysed Analysis Asymptomatic Cohort Concordance coronavirus correlation COVID-19 testing demonstrated detect extraction-free method gene target gold standard greater hospital invasive less matching Nasopharyngeal swab nasopharyngeal swabs NPs nucleic acid participant Population positive processed protocol RdRP recruited Result RNA RT-qPCR Saliva saliva specimens saliva test SalivaDirect SARS-CoV-2 SARS-CoV-2 testing SARS-CoV2 sensitivity significant difference specificity specimens symptomatic Symptomatic patients [DOI] 10.12688/hrbopenres.13353.2 PMC 바로가기 [Article Type] Research Article
Rapid COVID-19 Molecular Diagnostic System Using Virus Enrichment PlatformArticle Published on 2021-10-062022-10-27 Journal: Biosensors [Category] COVID-19, [키워드] Accuracy acute respiratory syndrome alleviate amplify caused Community coronavirus coronavirus disease COVID-19 detect diagnosis of COVID-19 diagnostic diagnostic test enrichment fluoride healthcare hydrophilic Infection isothermal amplification lateral flow molecular molecular diagnostics nasopharyngeal nucleic acid amplification pandemic pandemic era platform Prevent public health Rapid rapid diagnostics reduce reverse transcription RNA RNA extraction robust sample preparation SARS-CoV-2 specimens Spread System therapeutic intervention virus virus enrichment [DOI] 10.3390/bios11100373 PMC 바로가기 [Article Type] Article
Rapid COVID-19 Molecular Diagnostic System Using Virus Enrichment PlatformArticle Published on 2021-10-062022-10-27 Journal: Biosensors [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] Accuracy acute respiratory syndrome alleviate amplify caused Community coronavirus coronavirus disease COVID-19 detect diagnosis of COVID-19 diagnostic diagnostic test enrichment fluoride healthcare hydrophilic Infection isothermal amplification lateral flow molecular molecular diagnostics nasopharyngeal nucleic acid amplification pandemic pandemic era platform Prevent public health Rapid rapid diagnostics reduce reverse transcription RNA RNA extraction robust sample preparation SARS-CoV-2 specimens Spread System therapeutic intervention virus virus enrichment [DOI] 10.3390/bios11100373 PMC 바로가기 [Article Type] Article
Rapid COVID-19 Molecular Diagnostic System Using Virus Enrichment Platform바이러스 농축 플랫폼을 사용한 빠른 CovID-19 분자 진단 시스템Article Published on 2021-10-062022-09-01 Journal: Biosensors [Category] 진단, 치료기술, 치료제, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus alleviate amplify caused clinic Community coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 detect diagnosis of COVID-19 diagnostic diagnostic test diagnostic tests enrichment fluoride hand healthcare hydrophilic Infection isothermal amplification LAMP lateral flow Loop-mediated isothermal amplification medical staff molecular molecular diagnostics myriad nasopharyngeal nucleic acid nucleic acid amplification pandemic pandemic era platform Prevent public health Rapid rapid diagnostics reduce respiratory reverse transcription RNA RNA extraction robust sample preparation SARS-CoV-2 severe acute respiratory syndrome Coronavirus specimens Spread System therapeutic intervention virus virus enrichment viruses [DOI] 10.3390/bios11100373 PMC 바로가기 [Article Type] Article
Reliable Diagnostics of SARS-CoV-2 Infections Using One- and Two-Gene Molecular Tests for a Viral RNA Detection—Results Questioning Previous ObservationsArticle Published on 2021-10-052022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] ORF1ab gene S gene 2019-nCoV Anatolia BD MAX™ System Becton Dickinson Biotechnology carried COVID-19 detection discrepancy E gene East effective evaluate evaluated Frequency Genes Inc. İstanbul new virus nine novel observation PCR positive product researcher RNA RNA detection SARS-CoV-2 SARS-CoV-2 RNA detection SARS-CoV-2 S gene sensitivity Spain specimens Spread statistically significant difference swabs System target gene Target genes Test the Coronaviridae time Turkey USA Viral RNA [DOI] 10.3390/diagnostics11101839 PMC 바로가기 [Article Type] Article
Bacterial and fungal ventilator associated pneumonia in critically ill COVID-19 patients during the second wave2차 유행 동안 중환자 COVID-19 환자의 박테리아 및 곰팡이 인공 호흡기 관련 폐렴Article Published on 2021-10-012022-09-11 Journal: Journal of infection and public health [Category] SARS, 치료기술, [키워드] 95% CI 95% confidence interval Acinetobacter admitted to ICU antimicrobial antimicrobial resistance antimicrobial susceptibility Aspergillus Bacteria Bacterial Bacterial infections Candida caused Chest collected coronavirus disease Corticosteroid Corticosteroids COVID-19 COVID-19 patient Critical Critically ill critically ill COVID-19 patients Culture diabetes Diabetes Mellitus diagnosed disease element followed by fungal fungi Hypothyroidism ICUs identify intensive care unit intensive care units isolate isolates Klebsiella pneumoniae MDR mechanical ventilation Mucor multi outcomes pandemic Patient PDR Pneumonia pneumoniae positive respiratory Respiratory samples risk factor Risk factors SARS-CoV2 second wave specimen specimens subsequent susceptibility Tocilizumab Treatment VAP ventilator Ventilator associated pneumonia [DOI] 10.1016/j.jiph.2021.08.003 PMC 바로가기 [Article Type] Article