Stem cell therapy for COVID-19: Possibilities and challengesReview Published on 2020-11-012023-07-12 Journal: Cell biology international [Category] SARS, [키워드] acellular therapy coronavirus COVID-19 Mesenchymal stem cells pandemic stem cells [DOI] 10.1002/cbin.11440 PMC 바로가기 [Article Type] Review
Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Platform to Study SARS-CoV-2 Related Myocardial InjuryArticle Published on 2020-10-232023-07-11 Journal: Circulation journal : official journal of the Japanese Circulation Society [Category] SARS, [키워드] COVID-19 myocarditis SARS-CoV-2 stem cells [DOI] 10.1253/circj.CJ-20-0881
Potential application of mesenchymal stem cells and their exosomes in lung injury: an emerging therapeutic option for COVID-19 patientsReview Published on 2020-10-152022-10-29 Journal: Stem Cell Research & Therapy [Category] COVID-19, MERS, SARS, [키워드] acute lung injury alveolar fluid clearance applicability approved ARDS characterized clinical study clinical trial clinical trials Consensus correlation COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients effective effective therapy Efficacy endothelial ENhance epithelial Exosome global public health highlight impacted Infection International less lung mechanism of action mesenchymal stem cell MSC MSC therapy MSCs Pneumonia Potential promote reduce Registered risk Safe SARS-CoV-2 stem cell stem cells the cytokine storm the SARS-CoV-2 therapeutic therapeutic effect therapeutic option therapy Thromboembolism treat treating COVID-19 patients Treatment unique [DOI] 10.1186/s13287-020-01963-6 PMC 바로가기 [Article Type] Review
Alveolar cells under mechanical stressed niche: critical contributors to pulmonary fibrosisReview Published on 2020-10-142022-10-30 Journal: Molecular Medicine [Category] Coronavirus, MERS, SARS, [키워드] Activation Alter alveolar cells alveolar epithelium arise capillary Cell cellular COVID-19 patient Critical cytoskeletal Effect endothelial cells Epigenetic epithelial epithelial cells Extracellular matrix fibroblast fibroblasts fibrosis Gas exchange generate Injury Local Lung fibrosis Macrophage Mast cells mechanical stress Mechanical stress niche mechanical ventilation Mild pathology pulmonary pulmonary fibrosis receive Regulation repeated severe hypoxemia stages stem cells subject subsequent Supportive treatment tissue variety vascular permeability [DOI] 10.1186/s10020-020-00223-w PMC 바로가기 [Article Type] Review
Structural Variants Create New Topological-Associated Domains and Ectopic Retinal Enhancer-Gene Contact in Dominant Retinitis Pigmentosa구조적 변이체는 우성 색소성 망막염에서 새로운 위상 관련 도메인 및 이소성 망막 인핸서-유전자 접촉을 생성합니다Article Published on 2020-10-052022-08-07 Journal: American Journal of Human Genetics [Category] 유전자 메커니즘, [키워드] adRP affected Altered binding site blindness breakpoint Cell characterized Chr17q22 complex Contact Control creation differential expression disease domain dominant dominant retinitis pigmentosa ectopic ectopic expression enhancer enhancers Epigenetic Families fibroblast fibroblasts Gain of function GDPD GDPD1 Genome sequencing genomic genomic region genotyping Hi-C highlight increased expression individual individuals investigated leads LINC01476 locus loss of vision mechanism Mendelian diseases modeling Molecular diagnosis New photoreceptor photoreceptor precursors cells pluripotent stem cell PPCs precursor qPCR resulting Retinal retinal enhancer retinal expression retinal organoid retinal organoids retinal-specific enhancer Retinitis retinitis pigmentosa RNA RP17 stem cells Structural variant structural variants SVs topologically associated domains transcription factors vision was performed whole-genome sequencing YPEL2 [DOI] 10.1016/j.ajhg.2020.09.002 PMC 바로가기 [Article Type] Article
Trends and targets of various types of stem cell derived transfusable RBC substitution therapy: Obstacles that need to be converted to opportunity다양한 형태의 줄기세포 유래 수혈적혈구 대체요법의 동향 및 목표: 기회로 전환되어야 할 장애물Review Published on 2020-10-012022-09-11 Journal: Transfusion and apheresis science : official journ [Category] 비임상, [키워드] approach artificial artificial intelligence Bioreactors Blood Blood Group blood supply breath Cell cellular clinical trial Combination complex Compliance COVID-19 Critical Culture dependency Donor Efficiency embryonic employment example expansion Expansion media GMP GMP regulatory processes hematological Hematopoietic stem cell hematopoietic stem cells highlight in vitro In-vitro induced Induced pluripotent stem cell life maintenance media metabolic pathway metabolic pathways metabolite metabolites New obstacle outbreak overcome pandemic produced RBC RBCs regenerative regenerative medicine Regulatory required Safe stability STEM stem cell stem cells target Transfusable RBC bioproducts. transfusion trend Variability [DOI] 10.1016/j.transci.2020.102941 PMC 바로가기 [Article Type] Review
Evaluation of pulmonary complications in patients undergoing allogenic stem cell transplantationResearch Published on 2020-10-012024-09-02 Journal: The Egyptian Journal of Bronchology [Category] 대상포진, [키워드] Allogenic transplantation pulmonary complications stem cells [DOI] 10.1186/s43168-020-00032-z PMC 바로가기 [Article Type] Research
The Potential Use of Mesenchymal Stem Cells and Their Derived Exosomes as Immunomodulatory Agents for COVID-19 PatientsReview Article Published on 2020-09-242022-10-29 Journal: Stem Cells International [Category] COVID-19, [키워드] acute respiratory disease acute respiratory distress acute respiratory syndrome adhere administration affected agent alveolar inflammation ARDS Bone marrow Cell cell-based therapies clinical trial coronavirus COVID-19 COVID-19 patient COVID-19 patients disease Efficacy epithelia example Exosome highlight lung injuries MSC MSCs pandemic pathological condition patients Pneumonia Potential Quality control respiratory tract risk SARS-CoV-2 shown significantly lower STEM stem cell stem cells Support syndrome therapeutic therapeutic potential therapy treating COVID-19 World Health Organization [DOI] 10.1155/2020/8835986 PMC 바로가기 [Article Type] Review Article
Infection of Brain Organoids and 2D Cortical Neurons with SARS-CoV-2 PseudovirusArticle Published on 2020-09-082022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] ACE2 Brain brain organoid brain organoids cortical cortical neuron COVID-19 embryonic expression host cell receptor increase in Infection lack mechanism Neural neurological Neuron neurons organ Organoid outbreak proportion pseudotyped SARS-CoV-2 pseudovirus reported SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 pseudovirus stem cells susceptibility sustained Symptom Viral load Viral particles were infected [DOI] 10.3390/v12091004 PMC 바로가기 [Article Type] Article
Immunomodulatory-based therapy as a potential promising treatment strategy against severe COVID-19 patients: A systematic reviewArticle Published on 2020-08-292022-10-04 Journal: International immunopharmacology [Category] MERS, SARS, 치료법, [키워드] acute respiratory syndrome antivirals available data carried clinical trial clinician Consensus coronavirus Corticosteroid Corticosteroids COVID-19 COVID-19 infection COVID-19 patients cytokine-targeted therapy database dosage effective effective therapy Efficacy eligible HCQ heterogeneous Hydroxychloroquine immune dysregulation immune system Immunomodulatory agents immunomodulatory drug immunomodulatory therapy Immunomodulatory-based therapy indicate inflammatory reactions information innate response Medicine Mesenchymal stem cells MSC novel coronavirus disease outbreak Panic Passive Passive immunotherapy provide reduce mortality regulate Safe SARS-CoV-2 severe COVID-19 severely ill patients severity Stage stem cell stem cells systematic literature search systematic review the disease Therapies therapy therapy for COVID-19 Treatment treatment approaches triggered Web of Science [DOI] 10.1016/j.intimp.2020.106942 PMC 바로가기 [Article Type] Article