Identification of NCAM that interacts with the PHE-CoV spike proteinResearch Published on 2010-09-242022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] adhesion antibody antiviral therapies association binding blocked cDNA library Cell cells cellular cellular molecule coronavirus Critical double-stranded found identification Infection inhibited interact Interaction molecule Neural Protein required Result S glycoproteins S protein screened siRNA Spike protein T7 target target cells viral life cycle virus infection [DOI] 10.1186/1743-422X-7-254 PMC 바로가기 [Article Type] Research
Mutagenesis of the transmembrane domain of the SARS coronavirus spike glycoprotein: refinement of the requirements for SARS coronavirus cell entryResearch Published on 2009-12-242022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] assays cell entry cell-cell fusion cells characteristic Critical cysteine cysteines described domain glycine hydrophobic investigated lysine membrane fusion motif Particle pseudotyped Receptor binding residue Result SARS Coronavirus SARS CoV SARS-CoV Spike protein target cells the S protein transmembrane domain viral membrane virus [DOI] 10.1186/1743-422X-6-230 PMC 바로가기 [Article Type] Research
Generation of human antibody fragments recognizing distinct epitopes of the nucleocapsid (N) SARS-CoV protein using a phage display approachResearch Article Published on 2005-09-192022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, [키워드] acute respiratory syndrome antibody antibody fragment Antiviral compound approach cause characterized coated with antigen described detect diagnostic test disease domain ELISA epitope Generation high mortality rate Human immunocytochemistry immunohistochemistry in vitro Infected Isolation MONITOR N protein neutralizing antibody nucleocapsid Particle Prevent Protein reagent recognize recognizing Result SARS epidemic SARS virus SARS-CoV SARS-CoV N protein scFv selected severe Spread target cells treat Vaccine Vero cells virus was used [DOI] 10.1186/1471-2334-5-73 PMC 바로가기 [Article Type] Research Article