Urinary cytokines correlate with acute kidney injury in critically ill COVID-19 patients비뇨기 사이토 카인은 중환자 Covid-19 환자에서 급성 신장 손상과 관련이 있습니다.Article Published on 2021-10-012022-08-31 Journal: Cytokine [Category] MERS, SARS, 바이오마커, [키워드] Acute kidney injury AKI analyzed Biomarker Biomarkers Clinical characteristics correlated correlation COVID-19 COVID-19 patient COVID-19 patients creatinine Critical Critical illness Critically ill cytokine cytokine level Cytokines ICU immune cell lineage immune cell lineages Inflammation Inflammatory cytokine Inflammatory cytokines intensive care investigated kidney Kidney injury kidney tissue marker multiplex Non-invasive Patient Proinflammatory cytokine proinflammatory cytokines renal damage significantly target upregulated upregulation urinary Urine was collected [DOI] 10.1016/j.cyto.2021.155589 PMC 바로가기 [Article Type] Article
CD99 and polymeric immunoglobulin receptor peptides deregulation in critical COVID-19: A potential link to molecular pathophysiology?중요한 COVID-19에서 CD99 및 고분자 면역글로불린 수용체 펩티드 규제 완화: 분자 병태생리학에 대한 잠재적 연결?Multicenter Study Published on 2021-10-012022-09-11 Journal: Proteomics [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] affected alpha-1-antitrypsin analysed antitrypsin capillary electrophoresis CD99 change changes collagen collected comparable Course COVID-19 COVID-19 disease Critical deregulation disease disease severity effective endothelial endothelial disease endothelial integrity Europe heart failure hypothese hypotheses identification Immunoglobulin induce Inflammation Kidney disease mass spectrometry mechanisms molecular Molecular Disease molecular mechanisms multicentre pathophysiological mechanism pathophysiology Patient PCR-confirmed COVID-19 patient PCR-confirmed COVID-19 patients peptide peptides PIGR Prospective Study receptor Restoring significant changes in significantly similarities similarity specific inflammation Stage Therapeutic approach tissue Urine WHO [DOI] 10.1002/pmic.202100133 PMC 바로가기 [Article Type] Multicenter Study
SGLT2-Inhibition reverts urinary peptide changes associated with severe COVID-19: An in-silico proof-of-principle of proteomics-based drug repurposingSGLT2-억제는 심각한 COVID-19와 관련된 요로 펩티드 변화를 되돌립니다: 프로테오믹스 기반 약물 용도 변경의 인-실리코 증거Article Published on 2021-10-012022-09-11 Journal: Proteomics [Category] MERS, SARS, 신약개발, 유전자 메커니즘, 진단, [키워드] approach change collected COVID-19 COVID-19 severity database dataset diagnostic drug Drug repurposing drug therapies drug treatment drugs Empagliflozin endothelial endothelial damage Germany Hypothesis in urine in vitro in-silico molecular observation participant patients without COVID-19 peptide peptides positive potential benefit potential benefits principle proof protective mechanisms proteome proteomics Randomized reflected Registered reversed selected severe COVID-19 SGLT2 inhibition significant changes in spironolactone Support Therapeutic benefit therapy Treatment trial testing Urine [DOI] 10.1002/pmic.202100160 PMC 바로가기 [Article Type] Article
The syndrome of inappropriate antidiuresis after vaccination against COVID-19: case reportCase Report Published on 2021-09-252022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] absence acute respiratory syndrome Administered anorexia Antidiuresis C-reactive protein Case report Clinical finding condition coronavirus COVID-19 vaccination creatinine described diagnosed Diagnosis effective euvolemic explained expressed fatigue Fever fluids Health hyponatremia inappropriate antidiuresis laboratory investigation male medications mRNA-based vaccine Pain Patient patients receiving regimen resolved serum osmolality serum sodium SIADH sodium symptomatic syndrome systemic reaction the patient the vaccine therapy TSH urea Urine Urine chemistry vaccination vital sign weakness worsened worsening [DOI] 10.1186/s12879-021-06690-8 PMC 바로가기 [Article Type] Case Report
The combined effect of green tea and α-glucosyl hesperidin in preventing obesity: a randomized placebo-controlled clinical trialArticle Published on 2021-09-242022-10-04 Journal: Scientific Reports [Category] 임상, [키워드] Asia Blood blood biochemical BMI body mass index clinical trial Combination dose double-blinded Effect effective EGCG elicit ENhance fat female green tea Health care healthy hematological investigated Japanese male obesity physiological effect Placebo placebo-controlled placebo-controlled clinical trial Prevent prevented Randomized reduced reported Safe Triglyceride Urine visceral Weight management [DOI] 10.1038/s41598-021-98612-6 PMC 바로가기 [Article Type] Article
Hypophosphatemia is an independent risk factor for AKI among hospitalized patients with COVID-19 infectionResearch Article Published on 2021-09-192022-10-28 Journal: Renal failure [Category] COVID-19, SARS, [키워드] 95% CI Acute kidney injury Admission age AKI albumin C-reactive protein clinical COVID-19 COVID-19 infection COVID-19 patient Cox regression analysis CRP decrease dysfunction eight enrolled evaluated Follow-up hospital Hospitalization hospitalized COVID-19 hospitalized patient hypophosphate hypophosphatemia ICU ICU Patients incidence increased risk independent risk factor Infection laboratory parameter lactate dehydrogenase LDH Lymphocyte count male non-ICU non-ICU patient occurred Older Patient patients patients hospitalized Pearson phosphate Platelet positively correlated procalcitonin Prothrombin time proximal proximal tubule renal renal function renal tubular Result Retrospective study risk factor Risk factors serum serum albumin subgroup analysis systemic urea uric acid Urine Volume were recorded with COVID-19 Wuhan, China [DOI] 10.1080/0886022X.2021.1979039 PMC 바로가기 [Article Type] Research Article
High-Frequency, High-Throughput Quantification of SARS-CoV-2 RNA in Wastewater Settled Solids at Eight Publicly Owned Treatment Works in Northern California Shows Strong Association with COVID-19 IncidenceResearch Article Published on 2021-09-142022-10-29 Journal: mSystems [Category] COVID-19, [키워드] access acute respiratory syndrome Analysis can be used collected Community comparable Concentration conducted coronavirus coronavirus disease correlated COVID-19 COVID-19 cases COVID-19 incidence Critical demonstrated detect detectable effort eight Epidemiology generate High-resolution Implementing incidence of COVID-19 incidence rate increase in infectious disease outbreak lab Laboratory log Mild normalized pathogen plant producing Prospective Study provided Result Retrospective study RNA RNA concentration Sample SARS-CoV-2 SARS-CoV-2 RNA Settled solids show Solid Strong Transmission Treatment Urine virus wastewater website with COVID-19 work [DOI] 10.1128/mSystems.00829-21 PMC 바로가기 [Article Type] Research Article
Platinum chloride-based viability RT-qPCR for SARS-CoV-2 detection in complex samples복잡한 샘플에서 SARS-CoV-2 검출을 위한 염화백금 기반 생존율 RT-qPCRArticle Published on 2021-09-132022-09-10 Journal: Scientific Reports [Category] SARS, 치료기술, 치료제, [키워드] amplification Analysis approach Biological techniques buffer complement Complete complex Compound Contact tracing COVID-19 detect develop Environmental microbiology Environmental sciences FIVE foster genomic RNA inactivated indicated infection risk Infectious virus inoculated marker Microbiology molecular Molecular biology molecular markers Nasopharyngeal swab nasopharyngeal swabs non-infectious outbreak Particle Platinum positive Prevent Prevention and control provide qPCR RNA RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 particle SARS-CoV-2 RNA screened social movement specimen Spread Stool targets tested Urine viability Viral viral shedding Virology viruses wastewater [DOI] 10.1038/s41598-021-97700-x PMC 바로가기 [Article Type] Article
Prevalence of primary bacterial co-infections among patients with COVID-19 in Brunei DarussalamCovid-19 Published on 2021-09-082022-10-28 Journal: Western Pacific Surveillance and Response Journal [Category] COVID-19, SARS, [키워드] Admission affected age bacterial co-infection Blood bloodstream Brunei chest X-ray Co-infection Comorbidity coronavirus disease COVID-19 COVID-19 patients CXR death determine died Dyspnoea Fever Infection less Lower multiorgan failure nausea/vomiting objective outcomes Patient patients patients with COVID-19 period prevalence Prevalence respiratory tract infection Result screened severe COVID-19 severe disease sputum Staphylococcus aureus Symptom Urine [DOI] 10.5365/wpsar.2021.12.3.856 PMC 바로가기 [Article Type] Covid-19
Acceptability and satisfaction towards self‐collection for chlamydia and gonorrhoea testing among transgender women in Tangerine Clinic, Thailand: shifting towards the new normalResearch Article Published on 2021-09-082022-10-31 Journal: Journal of the International AIDS Society [Category] Coronavirus, SARS, [키워드] acceptability anatomical Care Chlamydia Chlamydia trachomatis clinic collected COVID‐19 determine eight enrolled evaluate genital gonorrhea Health Service implementation Infection infections information men Neisseria gonorrhoeae nucleic acid amplification offered pandemic participant pharyngeal physical distancing questionnaire receive rectal reported Result Satisfaction self‐collection Sex sexual intercourse shifting Support Swab Tangerine Transgender women transmitted Urine were used women [DOI] 10.1002/jia2.25801 PMC 바로가기 [Article Type] Research Article