Solar UV-B/A radiation is highly effective in inactivating SARS-CoV-2Article Published on 2021-07-202022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] Atmospheric science average characteristic Concentration diffusion earth effective Epidemics Epidemiology intensity less lower mortality Mortality mortality data outbreak Pandemics Radiation recorded Region SARS-CoV-2 single-stranded RNA virus Single-stranded RNA viruses Solar Solar physics TCID the SARS-CoV-2 UV light virion virucidal virus viruses [DOI] 10.1038/s41598-021-94417-9 PMC 바로가기 [Article Type] Article
SARS-CoV-2: preliminary study of infected human nasopharyngeal tissue by high resolution microscopyShort Report Published on 2021-07-182022-10-28 Journal: Virology Journal [Category] COVID-19, SARS, [키워드] AFM Algorithm Anosmia Antigen apical cell Asymptomatic atomic cell cultures cell membrane characteristic collected confocal microscopy coronavirus COVID-19 etiological agent expected explain healthy High-resolution improvement in some individuals mathematical Microscopy microvilli morphology Nasal Epithelial cells nasopharyngeal nasopharyngeal sample negative control Novel coronavirus novel coronavirus SARS-CoV-2 Particle patients performed positive positive sample processed regions reported Result RT-PCR Sample SARS CoV-2 SARS-CoV SARS-CoV-2 SEM specimen structures supplementary material Swab symptomatic tissue Transmission treated virion virus zone [DOI] 10.1186/s12985-021-01620-1 PMC 바로가기 [Article Type] Short Report
Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in Turkey비활성화된 전체 비리온 SARS-CoV-2 백신(CoronaVac)의 효능 및 안전성: 터키에서 이중 맹검, 무작위, 위약 대조, 3상 시험의 중간 결과Clinical Trial Published on 2021-07-172022-09-12 Journal: Lancet (London, England) [Category] Fulltext, SARS, 임상, 진단, [키워드] 1:1 95% CI adverse event adverse events antibody test result bleeding disorders blood product clinical trial Cohort component CoronaVac COVID-19 criteria dose double-blind Efficacy Efficacy and safety enrolled exclusion fatality fatigue follow-up period Frequency health-care humoral hydroxide Immunoglobulin immunosuppressive inactivated individual intention-to-treat intention-to-treat population intramuscularly IQR Local median Negative PCR nine Older outcome Pain participant PCR-confirmed per 1000 person-years per protocol Phase 3 phase 3 trial Placebo placebo-controlled protocol provided randomised Randomly recruited Registered reported safety analysis safety profile SARS-CoV-2 screened second dose shown Steroids symptomatic the placebo group the vaccine therapy Tolerability trials Turkey Vaccine virion virus Volunteer whole-virion SARS-CoV-2 vaccine yielding [DOI] 10.1016/S0140-6736(21)01429-X PMC 바로가기 [Article Type] Clinical Trial
Binding of SARS-CoV-2 Fusion Peptide to Host Endosome and Plasma MembraneArticle Published on 2021-07-132022-10-29 Journal: The journal of physical chemistry. B [Category] COVID-19, SARS, [키워드] acting bind binding C-terminus cellular membrane cleavage Connected conserved Contact eight element endosome flexible linker function fusion fusion peptide Host host cell host cell receptor human host identify Infection initial insertion MD simulation membrane membrane fusion molecular Multiple N-terminus plasma membranes proceed promote Protein required S1 domain S2′ site SARS-CoV-2 second stability subsequent the SARS-CoV-2 the SARS-CoV-2 virus viral envelope viral membrane viral spike virion virus [DOI] 10.1021/acs.jpcb.1c04176 PMC 바로가기 [Article Type] Article
COVID-19: Myths and RealityCovid-19 : 신화와 현실Review Published on 2021-07-082022-09-10 Journal: Biochemistry. Biokhimiia [Category] SARS, 유전자 메커니즘, 치료법, [키워드] ACE2 Activation angiotensin antagonists Antigen Antiviral approved binding affinity caused Cell cell membrane cell types cellular receptors Characteristics COVID‐19 COVID‑19 vaccine COVID‑19 cytoplasm facilitation feature Features furin-like protease fusion global public health hemagglutinin highly pathogenic human Angiotensin-converting enzyme hypothetical immune system immune system evasion immunological infectious agent Influenza Influenza virus Interaction mechanism molecular myth open other coronavirus other coronaviruses outbreak pandemic Pathogenesis pathogenic physiological pre-fusion Protein RBD reagents REALITY receptor Receptor binding Receptor-binding domain receptors Respiratory disease S protein SARS‑CoV‑2 similarity Strains Structure surface antigen the cell the RBD the receptor-binding domain the S protein the vaccine the viral nucleocapsid transition Treatment Trigger triggers vaccine production Vaccines Viral viral envelope virion virions virus viruses [DOI] 10.1134/S0006297921070026 PMC 바로가기 [Article Type] Review
First molecular-based detection of SARS-CoV-2 virus in the field-collected housefliesArticle Published on 2021-07-062022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] Blood conducted Diseases Fly homogenized hospital housefly Infection insect Iran Man metabolism Microbiology Molecular biology Musca domestica Pathogenesis PCR assay positive preliminary finding real-time PCR assay RNA SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 virions SARS-CoV-2 virus specimen survived tested the patient the SARS-CoV-2 the SARS-CoV-2 virus tissue sample Transmission treating COVID-19 patients virion warm Zoology [DOI] 10.1038/s41598-021-93439-7 PMC 바로가기 [Article Type] Article
In silico approach for identifying natural lead molecules against SARS-COV-2Article Published on 2021-07-012022-10-04 Journal: Journal of molecular graphics & modelling [Category] SARS, 신약개발, [키워드] 6LU7 Analysis approach binding energy caused Compound contributed COVID-19 COVID-19 disease database Drug discovery functional protein highest binding affinity impacted in silico indicated lab M pro main protease molecular molecular dynamics natural natural products parameters PDB Pharmacokinetic parameters. physiological platform polyprotein Prevent producing protease reduce relative Replication responsible SARS-CoV-2 screened survival target the SARS-CoV-2 virus therapeutic threat Vaccine viral disease virion [DOI] 10.1016/j.jmgm.2021.107916 PMC 바로가기 [Article Type] Article
The Role of Indoor Plants in air Purification and Human Health in the Context of COVID-19 Pandemic: A Proposal for a Novel Line of InquiryMolecular Biosciences Published on 2021-06-302022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] acute respiratory syndrome aerosol air-purification consequence Context coronavirus COVID-19 COVID-19 pandemic death Effect facial feasible filtration Health hospitalisation Human human health Humidity indoor plants infection rate limit LINE Mask measure microbes mitigate novel pandemic Particle phytoremediation plant purification reducing role SARS CoV-2 SARS-CoV-2 social distancing Spread spread of COVID-19 Transmission transmission rate variety viral spread virion virus [DOI] 10.3389/fmolb.2021.709395 PMC 바로가기 [Article Type] Molecular Biosciences
Identification of SARS‐CoV‐2 RNA in healthcare heating, ventilation, and air conditioning unitsOriginal Article Published on 2021-06-292022-10-30 Journal: Indoor air [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Aerosols component coronavirus coronavirus disease COVID‐19 COVID‐19 determine evaluated event facilitate filtration Guidance handling healthcare hospital HVAC identification indicate MERV operator Patient raise RNA SARS‐CoV‐2 SARS‐CoV‐2 specimens Surveillance transfer Transmission Travel treated utility Ventilation viral infectivity viral particle viral presence Viral RNA Viral transmission virion while [DOI] 10.1111/ina.12898 PMC 바로가기 [Article Type] Original Article
Man-Specific Lectins from Plants, Fungi, Algae and Cyanobacteria, as Potential Blockers for SARS-CoV, MERS-CoV and SARS-CoV-2 (COVID-19) Coronaviruses: Biomedical PerspectivesReview Published on 2021-06-282022-10-31 Journal: Cells [Category] COVID-19, MERS, SARS, [키워드] ACE2 Algae algae lectins Analysis Angiotensin-converting enzyme artocarpin Bacteria biomedical applications blocker CD23 complex coronavirus Coronavirus infection Coronaviruses COVID-19 cyanobacteria cyanobacteria lectins dipeptidyl peptidase East fungi fungi lectins glycan glycans glycosylated high-mannose host cell host cells include infect lectin mannose-specific lectins MERS MERS-CoV pea lectin plant lectins plants Potential probe Protein RBD Receptor binding domain receptors recognize respiratory responsible S protein S proteins SARS-CoV SARS-CoV-2 SARS-CoV-2 virions snowdrop lectin specificity spike spikes virion [DOI] 10.3390/cells10071619 PMC 바로가기 [Article Type] Review