Utilizing the electronic health records to create a syndromic staff surveillance system during the COVID-19 outbreakCOVID-19 발생 시 전자 건강 기록을 활용하여 증후군 직원 감시 시스템 구축Article Published on 2021-06-012022-09-11 Journal: American journal of infection control [Category] SARS, 치료기술, [키워드] Acute respiratory infection Aggressive ARI caused Cluster Clusters Community Contact tracing COVID-19 COVID-19 infection COVID-19 outbreak COVID-19 pandemic detect Effectiveness Electronic health record feasibility HCW HCWs Health health record healthcare healthcare worker Healthcare workers identify Infection prevention Intervention investigated Local onward transmission over Prevent respiratory respiratory infection respiratory infections Singapore Spread staff Surveillance Syndromic surveillance Workplace worldwide pandemic [DOI] 10.1016/j.ajic.2020.11.003 PMC 바로가기 [Article Type] Article
Production of anti-SARS-CoV-2 hyperimmune globulin from convalescent plasma회복기 혈장에서 항-SARS-CoV-2 과면역 글로불린 생산Article Published on 2021-06-012022-09-12 Journal: Transfusion [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome administration adverse event anti-SARS-CoV-2 antibody China clinical study Concentration convalescent convalescent plasma coronavirus COVID-19 COVID-19 convalescent hyperimmune Diseases enzyme-linked immunosorbent evaluated Final forms greater hIVIG hyperimmune IgA IgG IgM immune immune globulin. Immunoglobulin Inpatient ITAC monomer Multiple neutralizing antibody plasma plasma administration processing Production Protein purification purified reduced Regulatory SARS-CoV-2 Spread therapy Treatment Vaccine virus Volume was collected was used worldwide pandemic [DOI] 10.1111/trf.16378 PMC 바로가기 [Article Type] Article
Bioactive Molecules of Tea as Potential Inhibitors for RNA-Dependent RNA Polymerase of SARS-CoV-2Medicine Published on 2021-05-312022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] antiviral drug antiviral drugs approach bioactive molecules catalytic center caused coronavirus disease COVID-19 COVID-19 patients Critical Drug repurposing enzyme identify in vitro in vivo Interaction medication molecular molecular docking studies molecule NTP nucleotide Potential RdRP residue RNA RNA-dependent RNA polymerase RNA-RdRp robust SARS-CoV-2 tea treat virus worldwide pandemic [DOI] 10.3389/fmed.2021.684020 PMC 바로가기 [Article Type] Medicine
The role of unconventional T cells in COVID-19Review Article Published on 2021-05-292022-10-30 Journal: Irish Journal of Medical Science [Category] COVID-19, COVID19(2023년), SARS, [키워드] Γδ T cells acute respiratory syndrome Anti-viral immunity Cancer caused Cell coronavirus COVID-19 disease effective vaccine help human SARS-CoV-2 immune response Immunotherapy Infection iNKT INKT cells MAIT cells mechanism mortality rate mucosal natural killer Pathogenesis protective role Respiratory disease SARS-CoV SARS-CoV-2 SARS-COV-2 infection Severe case shown T cell T cell subset T cells T lymphocytes therapeutic agent these cell Treatment strategies Unconventional T cells viral replication virion virus worldwide pandemic [DOI] 10.1007/s11845-021-02653-9 PMC 바로가기 [Article Type] Review Article
SARS-CoV-2-Induced Gut Microbiome Dysbiosis: Implications for Colorectal CancerReview Published on 2021-05-282022-10-31 Journal: Cancers [Category] COVID-19, [키워드] acute respiratory syndrome Bacteremia Bacteria Butyrate Cancer cancer patient cancer treatment cause change colonic Colorectal Colorectal cancer Coronavirus disease-19 Coronavirus-2 COVID-19 death develop Diagnosis Effect Evidence exacerbating expression of gene Fusobacterium greater Guidance Gut gut microbiome gut microbiota Health Immunosuppression Impact individuals without cancer Infection infection with SARS-CoV-2 Inflammation investigation knowledge long-lasting microbial microbiota mortality rate Novel coronavirus pathogen Patient progression resulting SARS-CoV-2 SARS-COV-2 infection severe COVID-19 shown simple Specific Treatment strategies tumorigenesis worldwide pandemic [DOI] 10.3390/cancers13112676 PMC 바로가기 [Article Type] Review
Traditional Herbal Medicines, Bioactive Metabolites, and Plant Products Against COVID-19: Update on Clinical Trials and Mechanism of ActionsPharmacology Published on 2021-05-282022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Action affecting Against Anti-COVID-19 Anti-infective anticancer therapies Antiviral antiviral properties approach approved Ayurved medicine bioactive metabolites clinical clinical trial conducted coronavirus COVID-19 develop drugs effective Efficacy eliminated global public health Herbal Hospitalization identify infective medications Medicine Medicines metabolite morbidity and mortality notable nutraceuticals pandemic phytochemicals Phytomedicine plant product reached researcher SARS-CoV-2 shown therapy Traditional Traditional Chinese medicine traditional Chinese medicines Vaccine Vaccines viral infection World Health Organization worldwide pandemic [DOI] 10.3389/fphar.2021.671498 PMC 바로가기 [Article Type] Pharmacology
Clinical features and prognostic factors of intensive and non-intensive 1014 COVID-19 patients: an experience cohort from Alahsa, Saudi Arabia집중 및 비집중 1014 COVID-19 환자의 임상 특징 및 예후 요인: 사우디아라비아 알라사의 경험 코호트Multicenter Study Published on 2021-05-242022-09-10 Journal: European Journal of Medical Research [Category] 진단, 치료제, [키워드] Admission age Alanine alanine aminotransferase alkaline Blood cells body temperature body temperatures Care Cell Characteristics Chest CT image clinical Clinical characteristics clinical decision Cohort cohort study Comorbidity conducted cough COVID-19 COVID-19 disease COVID-19 patient Critical Critical care decreased hemoglobin determine diabete diabetes disease Dizziness elevated fatigue feature ferritin Fever group groups had more Healthcare provider hemoglobin high mortality hospital hospitalized patient hospitalized patients hypertension ICU ICU admission ICU patient ICU Patients identifying Intensive laboratory-confirmed Lactate lactate dehydrogenase males medical record medical records Mortality mortality rate much higher Neutrophils non-ICU obesity objective Older age outcomes Patient predict predictor prevalent Prognostic factor proportion respiratory rate respiratory rates Result SARS-CoV-2 Saudi Arabia severe COVID-19 disease Shortness of breath sickle cell Sickle cell disease Significant significant difference significant differences smoker Symptom Treatment vomiting White blood cells worldwide pandemic [DOI] 10.1186/s40001-021-00517-7 PMC 바로가기 [Article Type] Multicenter Study
The Emerging Concern and Interest SARS-CoV-2 VariantsReview Published on 2021-05-212022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] acute respiratory syndrome Analysis B.1.1.7 B.1.351 B.1.525 B.1.526 CDC center close monitoring concern concerning conditions contagious Control coronavirus coronavirus disease COVID-19 defined disease group immune information interest mutations P.1 P.2 prevention public health responsible risk RNA viruses SARS-CoV-2 SARS-CoV-2 variants severity Spread susceptibility variant variants variants of concern variants of interest virus WHO World Health Organization worldwide pandemic Wuhan, China [DOI] 10.3390/pathogens10060633 PMC 바로가기 [Article Type] Review
Health Sufficiency Indicators for Pandemic MonitoringArticle Published on 2021-05-182022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] accumulated addition affected applied arising Care Characteristics comparison country COVID-19 COVID-19 disease disease evaluate Evolution First wave fusion of information Health health system health systems hospital ward hospitals ICU Indicator indicators information International introduced measure monitoring National Occupancy outbreak pandemic performed Potential Ratio regions Spanish the disease Time series to define Transmission worldwide pandemic [DOI] 10.3390/ijerph18105358 PMC 바로가기 [Article Type] Article
Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis게놈 전반에 걸친 생물정보학 분석으로 SARS-CoV-2 발병의 주요 숙주 및 바이러스 요인 예측Article Published on 2021-05-172022-09-10 Journal: Communications Biology [Category] SARS, 변종, 유전자 메커니즘, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus age Analysis analyzed Betacoronavirus caused Computational biology and bioinformatics conserved contribute coronavirus COVID-19 CSF2 differentially expressed eIF4b eukaryotic Factor Genes help heterogeneous hnRNPA1 Host host gene expression host response host–pathogen interactions human gene human genes human respiratory cell human respiratory cells identify IL-6 IL32 Infection initiation factor interact Interaction isoform isoforms life cycle mechanism novel Betacoronavirus nuclear predict predicted Protein reduce respiratory respiratory cells ribonucleoprotein RNA SARS-CoV-2 SARS-CoV-2 genome SARS-COV-2 infection SARS-CoV-2 pathogenesis sequence sequencing data SERPINA3 severe acute respiratory syndrome Coronavirus severity of COVID-19 statistically significant the SARS-CoV-2 genome Therapeutics transcriptomics transposable element upregulated variant Viral viral genome sequence viral infection viral life cycle Viral RNA worldwide pandemic Wuhan Wuhan, China [DOI] 10.1038/s42003-021-02095-0 PMC 바로가기 [Article Type] Article