Update on Antiviral Strategies Against COVID-19: Unmet Needs and ProspectsCOVID-19에 대한 항바이러스 전략에 대한 업데이트: 충족되지 않은 요구 및 전망Review Published on 2021-02-052022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 치료제, [키워드] Against Antiviral antiviral efficacy approved candidate caused Clinical studies clinical trials confirmed case Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 pandemic death drug effective Emergency use examined exhibited focus highlight in vitro in vivo inhibitor management outbreak over patients Research severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Strategy the vaccine therapeutic therapeutic agent therapeutic agents Transmission Treatment vaccine candidates [DOI] 10.3389/fimmu.2020.616595 PMC 바로가기 [Article Type] Review
Rational design of multi epitope-based subunit vaccine by exploring MERS-COV proteome: Reverse vaccinology and molecular docking approachResearch Article Published on 2021-02-032022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] AAY antigenic antigenicity Antiviral applied approach B-cell binding caused characteristic conserved coronavirus correlated docked Efficiency elicit epitope Epitopes examined expression Host IFN-γ immunogenic potential immunogenic profile in-silico Infection Infection prevention Isolation linker mechanism membrane MERS-CoV MERS-CoV infection MERS-CoV vaccine Middle East molecular docking mortality rate multi multiepitope vaccine N-terminal non-homologous non-structural protein ORF1a ORF3 ORF8 positive receptor Region RNA virus Saudi Arabia selected selected epitope Seven single-stranded South Korea structural protein subunit syndrome T-cell T-cell responses the vaccine tlr-3 Toll-like receptor 3 Treatment unique Vaccine Viral protein were recorded β-defensin [DOI] 10.1371/journal.pone.0245072 PMC 바로가기 [Article Type] Research Article
COVID-19 Vaccine Acceptance among Health Care Workers in the United StatesArticle Published on 2021-02-032022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acceptance Analysis black Care collected combating Complete conducted COVID-19 COVID-19 vaccination COVID-19 vaccine cross Direct Effectiveness female Final HCW HCWs healthcare worker Healthcare workers increasing age pandemic receive response Safety study population the United State the vaccine United States vaccination Vaccine widespread worker [DOI] 10.3390/vaccines9020119 PMC 바로가기 [Article Type] Article
Small animal jet injection technique results in enhanced immunogenicity of hantavirus DNA vaccinesResearch article Published on 2021-02-012022-10-05 Journal: Vaccine [Category] 비임상, [키워드] administer Administered Ande antigen expression disease DNA vaccine Efficacy epidermal evaluated fibroblast cells gene gun hamster hamsters hantavirus immunogenic immunogenicity Increased immunogenicity injection intramuscular Jet injection lethal disease medical countermeasure Medicine mRNA stability nucleic acid optimization overcome Protective RNA shown tested the vaccine tissues Tropis vaccination Vaccine virus Volume was used [DOI] 10.1016/j.vaccine.2021.01.002 [Article Type] Research article
Strategy drives implementation: COVID vaccination in IsraelCommentary Published on 2021-02-012022-10-30 Journal: Israel Journal of Health Policy Research [Category] Coronavirus, MERS, [키워드] Comparative health systems COVID COVID-19 Effectiveness facilitated Healthcare system implementation key factor National Rosen Strategy the vaccine United States government vaccination [DOI] 10.1186/s13584-021-00445-1 PMC 바로가기 [Article Type] Commentary
Timing of COVID-19 vaccine approval and endorsement by public figuresCOVID-19 백신 승인 및 공인의 승인 시기Article Published on 2021-01-292022-08-31 Journal: Vaccine [Category] MERS, 신약개발, [키워드] approval confidence COVID-19 COVID-19 vaccine effective Efficacy Endorsements experiments increase pair pandemic Politicization Randomized receive reduce Safe significantly spread of COVID-19 subgroups The United States the vaccine United States Vaccine Vaccine hesitancy viability [DOI] 10.1016/j.vaccine.2020.12.048 PMC 바로가기 [Article Type] Article
Immune response scenario and vaccine development for SARS-CoV-2 infectionReview Published on 2021-01-292022-11-01 Journal: International immunopharmacology [Category] COVID-19, MERS, SARS, [키워드] antiviral drug approach asymptomatic infection build caused China clinical presentation Complete Coronavirus infection COVID-19 COVID-19 pandemic Cytokine storm death disease Disease progression effective Effectiveness element flu Health helping immune response immune system in viral in vitro include induce management MERS multiple organ failure natural immune response Neutralizing Novel coronavirus patient’s death Pneumonia Prevent promoter Prophylaxis Protein protein S Randomized responsible SARS CoV-2 SARS-CoV-2 SARS-COV-2 infection spike glycoprotein supportive care Symptom the vaccine therapy treat Trial Vaccine Vaccine development Vaccines while [DOI] 10.1016/j.intimp.2021.107439 PMC 바로가기 [Article Type] Review
Psychological and Behavioral Predictors of Vaccine Efficacy: Considerations for COVID-19Article Published on 2021-01-272022-10-29 Journal: Perspectives on Psychological Science [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome boost Characteristics coronavirus COVID-19 COVID-19 pandemic demonstrated Depression Efficacy evaluated Evidence Factor group Health health behaviors highest immune Immunity impair implicated Intervention loneliness over Prevalence prevalent Psychological Psychological factor receive recent reduce Research risk factor SARS-CoV-2 severity Side effects Stress the SARS-CoV-2 the vaccine Vaccine vaccine candidate vaccine efficacy vaccine response vaccine responses Vaccines [DOI] 10.1177/1745691621989243 PMC 바로가기 [Article Type] Article
Induction of SARS-CoV-2 Protein S-Specific CD8+ T Cells in the Lungs of gp96-Ig-S Vaccinated Micegp96-Ig-S 백신 접종 마우스의 폐에서 SARS-CoV-2 단백질 S-특이적 CD8+ T 세포의 유도Immunology Published on 2021-01-262022-09-12 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, [키워드] airways Allogeneic Antigen CD4+ CD8+ CD8+ T cell CD8+ T cells Cell Cell-mediated immune responses cellular Cellular immune response chaperone COVID-19 deaths expressing full-length protein generate glycoprotein glycoprotein 96 Heat shock heat shock protein humans immune system IMPROVE induce induction leukocyte lung Lungs measure observation Protein protein S public health response robust SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 protein SARS-CoV-2 protein S secreted Spread stimulate Support the vaccine transgenic mice translational Vaccine vaccine candidate vaccine platform [DOI] 10.3389/fimmu.2020.602254 PMC 바로가기 [Article Type] Immunology
Membrane Microvesicles as Potential Vaccine CandidatesReview Published on 2021-01-242022-10-29 Journal: International Journal of Molecular Sciences [Category] Coronavirus, [키워드] addition Antigen approach Bacterial pathogens biogenesis candidate cellular immune responses criterion Delivery system demonstrated Diseases effective Efficacy healthcare humoral immune Immunity immunogenic Infection Infectious disease Infectious diseases injection mechanism microvesicle Microvesicles nucleic acid organ outbreak Pandemics polysaccharide Potential PROTECT Proteins public health SARS-CoV-2 suggested target cells the vaccine Vaccine [DOI] 10.3390/ijms22031142 PMC 바로가기 [Article Type] Review