cohort study – Page 133 – Communicable Diseases Research

COVID-19 in cancer patients: clinical characteristics and outcome—an analysis of the LEOSS registry

암 환자의 COVID-19: 임상 특성 및 결과 - LEOSS 레지스트리 분석

Multicenter Study

Published on 2020-11-072022-09-10
Journal: Annals of Hematology [Category] MERS, SARS, 치료기술,

Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis

Meta-Analysis

Published on 2020-11-052022-10-04
Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 임상, 진단,

[키워드] 95%CI adjusted adjusted RR adverse event approach association certainty of evidence citation Cohort cohort study cohorts concerning Controlled COVID-19 COVID-19 patients COVID-19 severity Daily death did not reduce Efficacy elevated eligibility criteria eligible evaluate evaluated Evidence examined FIVE Google higher risk hospitalized COVID-19 patients IL-6 IL-6 receptor Infection interleukin-6 lower mortality mechanical ventilation Meta-analysis moderate Mortality Multiorgan objective observational study observé Other OVID participant Patient patients Placebo Randomized controlled trial RCT RCTs reduce Result risk risk of bia Risk of bias risk ratio RRs severe coronavirus disease Standard of care syndrome systematic review Tocilizumab Toxicity treat Treatment Web of Science while
[DOI] 10.1016/j.cmi.2020.10.036 PMC 바로가기 [Article Type] Meta-Analysis

Is older age associated with COVID-19 mortality in the absence of other risk factors? General population cohort study of 470,034 participants

다른 위험 요소가 없는 경우 고령이 COVID-19 사망률과 관련이 있습니까? 470,034명의 참가자를 대상으로 한 일반 인구 코호트 연구

Research Article

Published on 2020-11-052022-08-13
Journal: PLoS ONE [Category] COVID-19, Medicine and Health Sciences, MERS, SARS,

[키워드] 95% CI absence age All participants association baseline baseline data cohort study COVID-19 COVID-19 mortality current deaths died Eligible participants expiratory explained Factor forced expiratory volume high systolic blood pressure higher risk increased mortality independent risk factor Low forced expiratory volume low handgrip strength mediators Mortality mortality risk much lower multiple long-term condition multiple long-term conditions Older Older adults Older age participant Participants Poisson regression reported Result risk risk factor Risk factors Systolic blood pressure UK biobank Volume was used with COVID-19
[DOI] 10.1371/journal.pone.0241824 PMC 바로가기 [Article Type] Research Article

Impact of tocilizumab administration on mortality in severe COVID-19

Article

Published on 2020-11-052022-10-04
Journal: Scientific Reports [Category] 신약개발, 임상, 치료법,

[키워드] 95% confidence interval age Analysis benefit biologics chronic pulmonary disease clinical trial cohort study Comorbidity contribute Control COVID-19 COVID-19 patients Cytokine storm dataset death Dementia Diabetes Mellitus died discharged disease Evidence exclusion criteria expired healthcare providers heart failure hospital immune response Impact in-hospital mortality Inclusion individuals with COVID-19 Inflammatory response male malignancy management Medical research Mortality Myocardial infarction novel coronavirus disease Odds ratio Patient patients with COVID-19 Primary outcome provide severe COVID-19 severity significantly more single-center stratified Support the patient therapeutic thought Tocilizumab tocilizumab administration was performed worldwide pandemic
[DOI] 10.1038/s41598-020-76187-y PMC 바로가기 [Article Type] Article

Biomarkers of Hypercoagulability and Endothelial Cell Activation in Patients with Severe COVID-19 Admitted at the Intensive Care Unit. the Roadmap-COVID-19 Prospective Observational Study

Conference abstract

Published on 2020-11-042022-10-05
Journal: Blood [Category] 바이오마커,

[키워드] Activation acute respiratory distress acute respiratory syndrome Algorithm Antithrombotic AP-HP ARDS Biomarker Blood coagulation calculated cause cellular change characterized clinically clotting factor Cluster Coagulation cohort study complications consecutive patient Control control group controls coronavirus coronavirus disease COVID-19 D-dimer decrease disease download effect of treatment endothelial Endothelial cell Endothelial dysfunction enrolled evaluate evaluated excessive inflammation expressing fibrinogen FVIII healthy individual Heparanase Hospitalized hypercoagulability ICU ICU admission ICU patient IL-6 IL-6 level increase indicate indicated inflammatory reaction Inhaled inhibitor intensive care unit intrinsic life-threatening LMWH management mandatory Microparticle moderate modify molecular weight monomer MRI Multisystem organ failure outcome Paris pathway Patient patients patients hospitalized patients with COVID-19 peak platelet activation Pneumonia Prospective Prospective Study Protein protein S ranged Ratio Respiratory failure Result SARS-CoV-2 SARS-COV-2 infection severe COVID-19 shown significant decrease significantly STABLE syndrome table TFPI the mean the patient thrombin Thromboprophylaxis university von Willebrand factor were assessed with COVID-19
[DOI] 10.1182/blood-2020-140275 [Article Type] Conference abstract

Impact of Covid-19 in pregnancy on mother’s psychological status and infant’s neurobehavioral development: a longitudinal cohort study in China

Research Article

Published on 2020-11-042022-10-28
Journal: BMC Medicine [Category] COVID-19, SARS,

[키워드] addition age association Breastfeeding Child early development China chose cohort study collected data concerning conducted COVID-19 Depression developmental developmental delay disorder disorders domain Evidence Follow-up Healthcare provider Impact induced abortion infection risk interquartile range IQR longitudinal cohort study Maternal Health median medical record Mental disorder mental health mother Neonatal NICU nucleic acid parents participated positive Post-traumatic stress disorder Pregnancy pregnant patient proportion Psychological quarantine questionnaire repeated researcher Result Sex significantly single-arm specimens throat swab transmission of SARS-CoV-2
[DOI] 10.1186/s12916-020-01825-1 PMC 바로가기 [Article Type] Research Article

COVID-19 Impact on Lymphoma Patients’ Clinical Outcomes – an Observational Cohort Study

Conference abstract

Published on 2020-11-042022-10-05
Journal: Blood [Category] 유전자 메커니즘,

[키워드] 30-Day mortality abnormality absolute neutrophil count active cancer advanced age age anti-CD20 therapy anti-CD20 treatment antibody Antibody test baseline board Cancer CD20 clinical clinical information Clinical outcome CLL cohort study conducted continuous variable contributing to cough COVID-19 COVID-19 diagnosis COVID-19 infection COVID-19 PCR test COVID-19 related mortality CRP current death demographic determine diabete diabetes Diagnosis died distribution DLBCL download Electronic health record equity ferritin Fever figure funding higher risk hypertension IgG antibody immune Immunity Impact indolent Infection Infinity IQR Kaplan-Meier method Kite Lymphocyte count lymphoma male Mann-Whitney marker mechanical ventilation median median age median time multicenter naïve number of comorbidities Observational cohort study Other outcome parameter Patient patients patients required hospitalization patients treated patients with SARS-CoV-2 Pearson performance status presenting symptom receive Regional repeated reported required retrospective risk Sample size SARS-CoV2 Seattle seronegative seropositive Shortness of breath shown significantly lower significantly more speaker subtype survival T cell tested the median therapy treated treated patient Treatment university variable variables viral shedding was obtained while with COVID-19
[DOI] 10.1182/blood-2020-141871 [Article Type] Conference abstract

Clinical characteristics and risk factors for in‐hospital mortality of lung cancer patients with COVID ‐19: A multicenter, retrospective, cohort study

Original Article

Published on 2020-11-032022-10-28
Journal: Thoracic cancer [Category] COVID-19, SARS,

[키워드] age Analysis Atypical cancer patient cardiac troponin Characteristics China clinical clinical feature Clinical features Clinical outcome clinician cohort study cough COVID COVID‐19 COVID‐19 died discharged dominant early stage elevated Features help hospital identify increased risk independent risk factor initial initial symptoms Laboratory lung cancer lung cancer patient males median Mortality multicenter multivariable analysis multivariable logistic regression nonsurvivors predict Prognosis Prolonged Prothrombin time Radiographic respiratory symptom Result retrospective risk factor Risk factors sensitivity Significant survivor Symptom unique were excluded were used
[DOI] 10.1111/1759-7714.13710 PMC 바로가기 [Article Type] Original Article

Effect of Combination Therapy of Hydroxychloroquine and Azithromycin on Mortality in Patients With COVID-19

Observational Study

Published on 2020-11-012022-10-05
Journal: Clinical and translational science [Category] SARS, 임상,

[키워드] 95% CI 95% confidence interval acute respiratory syndrome age Azithromycin azithromycin treatment C reactive protein cohort study Combination combination treatment Comorbidities consecutive patient contraindications coronavirus coronavirus disease COVID-19 death drug Effect Evidence hazard ratio HCQ In-hospital death in-hospital mortality Infection Kaplan-Meier curve log rank test multivariable patients treated performed Pneumonia positive airway pressure primary end point randomized trial receive recorded reduced regression analysis retrospective SARS-CoV-2 single-center the median Treatment treatment group use of hydroxychloroquine women
[DOI] 10.1111/cts.12860 PMC 바로가기 [Article Type] Observational Study

Fasting blood glucose level is a predictor of mortality in patients with COVID-19 independent of diabetes history

Clinical Trial

Published on 2020-11-012022-10-05
Journal: Diabetes research and clinical practice [Category] SARS, 임상,

[키워드] analyzed association Blood blood glucose clinical laboratory cohort study collected conducted coronavirus disease Coronavirus disease 2019 COVID-19 diabete diabetes disease effective enrolled evaluate fasting fasting blood Fasting blood glucose Glucose hazard ratio hospitalized patient independent independent risk factor indicated Inpatient laboratory-confirmed Mortality multivariate outcome Patient patients with COVID-19 positive predicted Prognosis prognosis of patient regression analysis Renmin Hospital risk factor single center Treatment university was performed with COVID-19 Wuhan Wuhan, China
[DOI] 10.1016/j.diabres.2020.108437 PMC 바로가기 [Article Type] Clinical Trial