COVID-19-like symptoms observed in Chinese tree shrews infected with SARS-CoV-2Article Published on 2020-09-182023-07-01 Journal: Zoological research [Category] SARS, [키워드] animal model COVID-19 SARS-CoV-2 / HCoV-19 susceptibility Tree shrews [DOI] 10.24272/j.issn.2095-8137.2020.053 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Infections and Impact of the COVID-19 Pandemic in Pregnancy and Breastfeeding: Results from an Observational Study in Primary Care in BelgiumArticle Published on 2020-09-172022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Affect affected Belgium Breastfeeding breastfeeding women breastmilk clinician community health services consequence coronavirus counseling COVID-19 cross-sectional eligible Epidemiology Evidence Impact indicated lockdown measure media negatively affected organization pandemic participated performed positive Pregnancy pregnant pregnant women primary care Primary Health Care public health reduced reported required responsible Result SARS-CoV-2 Social support Support susceptibility tested women [DOI] 10.3390/ijerph17186766 PMC 바로가기 [Article Type] Article
Using BCG vaccine to enhance non-specific protection of health care workers during the COVID-19 pandemic: A structured summary of a study protocol for a randomised controlled trial in DenmarkLetter Published on 2020-09-172022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] 1:1 24 hour Administered administration age All participant allergy anti-cytokine therapy approved asked Bacterial infection BCG BCG vaccination blinded to treatment block Bone marrow Chemotherapy component Controlled trial COVID-19 COVID-19 pandemic criteria cumulative current daily dose Day defined Denmark Direct dissemination dose Effect element eligible ENhance EudraCT excluded exclusion group HCW Health care Health care worker HIV-1 hospital Hospital admission hospitals Human immunodeficiency virus Immunocompromised immunodeficiency incidence Inclusion infected with SARS-CoV-2 Infection infections Infectious disease injection Intervention intravenous lymphoma malignancy Medicine meet morbidity and mortality mycobacterial Mycobacterium tuberculosis NaCl solution non-specific not blinded number participant physician Placebo Prednisone Prevent protective effect protocol random randomisation randomised randomised controlled trial receive recruit reduce reductions in Registered reported resuspended Sample secondary Serious Adverse Event severity of COVID-19 Sex solid organ transplantation steroid Stratification study participant Study protocol subject subjects susceptibility suspicion Treatment Trial Tuberculosis Vaccine Vaccines website [DOI] 10.1186/s13063-020-04714-3 PMC 바로가기 [Article Type] Letter
Outcomes and Laboratory and Clinical Findings of Asthma and Allergic Patients Admitted With Covid-19 in a Spanish University HospitalPharmacology Published on 2020-09-162022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Admission allergic disease allergy analyzed Asthma blocker clinical clinical evolution Clinical outcome co-morbidities collected Comorbidity consecutive patient Coronavirus disease 2019 D-dimer value disorder finding hospital Hospital stay Hospitalization Hospitalized ICU individual inhibitor intensive care unit interleukin-6 Laboratory less leukocyte Mortality Older age oral anticoagulant outcomes oxygen saturation Patient patients radiological radiological finding reported risk selective serotonin reuptake inhibitor severe acute respiratory syndrome coronavirus 2 Spain Spanish susceptibility Symptoms therapy Treatment university [DOI] 10.3389/fphar.2020.570721 PMC 바로가기 [Article Type] Pharmacology
Gender susceptibility to COVID-19: a review of the putative role of sex hormones and X chromosomeCOVID-19에 대한 성 감수성: 성 호르몬과 X 염색체의 추정 역할에 대한 검토Review Published on 2020-09-162022-09-10 Journal: Journal of Endocrinological Investigation [Category] 유전자 메커니즘, [키워드] ACE2 ACE2 expression Analysis androgen androgens angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 COVID-19 COVID-19 infection death disease Endocrine Estrogen Estrogens Evidence Evolution explain females Gender Genetic health emergency Hypothesis in viral inactivation increased expression Infection infection rate involved Italy lethality maintain male mechanism men men and women Methylation Patient positive protective factor RAS reduced Regulation Regulatory reported representing Result SARS-CoV-2 entry Serine serine protease serine protease TMPRSS2 severity Sex Sex chromosome sex chromosomes sex hormone Sex hormones susceptibility TMPRSS2 TMPRSS2 expression Trojan horse Viral viral infection women X chromosome [DOI] 10.1007/s40618-020-01383-6 PMC 바로가기 [Article Type] Review
Most frequent South Asian haplotypes of ACE2 share identity by descent with East Eurasian populationsACE2의 가장 빈번한 남아시아 일배체형은 동 유라시아 인구와 강하하여 동일성을 공유합니다.Research Article Published on 2020-09-162022-08-13 Journal: PLoS ONE [Category] MERS, SARS, 유전자 메커니즘, [키워드] ACE2 Affect analysed Analysis angiotensin Asia Asians coronavirus coronavirus SARS-CoV-2 East enzyme Europeans Frequency Haplotype host susceptibility human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 identity by descent involved majority MOST Novel coronavirus novel coronavirus SARS-CoV-2 Phylogenetic analysis polymorphism Population populations receptor rs2285666 sequence shown SNP SNPs South South Asian suggested susceptibility unique Variation West [DOI] 10.1371/journal.pone.0238255 PMC 바로가기 [Article Type] Research Article
Correlation of the two most frequent HLA haplotypes in the Italian population to the differential regional incidence of Covid-19Research Published on 2020-09-152022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, SARS, [키워드] Affect affected analysed Analysis bone correlation country Course Covid-19 incidence and mortality disease distribution epidemiological explain Frequency geographical distribution Haplotype help higher risk HLA HLA haplotype HLA polymorphism HLA polymorphisms HLA typing HLA-A identify incidence individual Infection Italian Italian population Italy Marrow Mortality National overlapping Pearson correlation performed positive Region registry Result severity susceptibility the disease the epidemic to define understanding [DOI] 10.1186/s12967-020-02515-5 PMC 바로가기 [Article Type] Research
Molecular simulation of SARS-CoV-2 spike protein binding to pangolin ACE2 or human ACE2 natural variants reveals altered susceptibility to infectionShort Communication Published on 2020-09-152022-10-30 Journal: The Journal of General Virology [Category] COVID-19, [키워드] ACE2 ACE2 variants binding binding affinity binding free energy change complex coronavirus database dbSNP Genes greater Human human ACE2 indicated Infection Missense molecular dynamic simulation Molecular dynamics simulation pangolin receptor reduced reduction in reveal SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein significant increase significantly lower single-nucleotide SNVs susceptibility variant Variation virus transmission wild-type [DOI] 10.1099/jgv.0.001452 PMC 바로가기 [Article Type] Short Communication
Lower levels of vitamin D are associated with SARS-CoV-2 infection and mortality in the Indian population: An observational studyArticle Published on 2020-09-142022-11-01 Journal: International immunopharmacology [Category] COVID-19, SARS, [키워드] 25-hydroxyvitamin D acute respiratory syndrome association carried coronavirus correlated COVID-19 COVID-19 mortality database deficiency distribution Google Scholar Government of India India Indian population Infection infection rate inverse correlation Lower majority material Mortality mortality data mortality rate Pearson correlation receive required Result SARS-CoV-2 SARS-COV-2 infection searched severity susceptibility the mean the SARS-CoV-2 viral disease Vitamin D vitamin D levels website [DOI] 10.1016/j.intimp.2020.107001 PMC 바로가기 [Article Type] Article
Evaluating of the association between ABO blood groups and coronavirus disease 2019 (COVID-19) in Iraqi patientsResearch Published on 2020-09-112022-11-01 Journal: The Egyptian Journal of Medical Human Genetics [Category] COVID-19, [키워드] 2019 novel coronavirus 2019-nCoV 95% CI ABO ABO blood group age association Biomarker Blood Group contrary Control coronavirus disease COVID-19 death Deceased develop Diagnosis disease Evaluating female Gender Genetic group healthy blood donors hospitalized COVID-19 increased risk male observation outcome pandemic coronavirus Patient patients polymorphic system Prevalence Probing regression analysis Result risk RNA significantly significantly increased susceptibility therapy was used [DOI] 10.1186/s43042-020-00097-x PMC 바로가기 [Article Type] Research