Parental Acceptability of COVID-19 Vaccination for Children Under the Age of 18 Years: Cross-Sectional Online SurveyOriginal Paper Published on 2020-12-302022-10-29 Journal: JMIR Pediatrics and Parenting [Category] COVID-19, [키워드] 95% CI acceptability adjusted odds ratio age Analysis AOR asked association Characteristics children children under the age of 18 years China Complete contribute COVID-19 COVID-19 vaccination COVID-19 vaccine cross-sectional expected factory Government Health authority information likelihood logistic regression model media multivariate objective pandemic parent parental parental acceptability parents participant Physical examination positive positive attitude Prevalence provided Public receive required Result Shenzhen social media influence Support survey the vaccine Theory of Planned Behavior Transparency Vaccinating vaccination Vaccine [DOI] 10.2196/24827 PMC 바로가기 [Article Type] Original Paper
Novel coronavirus pneumonia (COVID-19) combined with Chinese and Western medicine based on ”Internal and External Relieving -Truncated Torsion” strategy신종 코로나바이러스 폐렴(COVID-19) '내외부 완화-절단 비틀림' 전략을 바탕으로 한·서양 의학 병행Multicenter Study Published on 2020-12-182022-08-31 Journal: Medicine [Category] 임상, 치료제, [키워드] 1:1 adverse event adverse events Antiviral Anxiety Baidu benefit caused China Chinese Clinical outcome cohort study Complication conducted control group coronavirus disease Coronavirus disease 2019 Coronavirus pneumonia Course COVID-19 COVID-19 patient disease Diseases Effect evaluate experimental group exterior and interior solutions External follow-up time general condition global pandemic Granule groups information internal mental health mental illness MONITOR novel Novel coronavirus novel coronavirus disease outbreak Patient physiological disorder primary diseases Primary outcome Primary outcomes prospective cohort study PROTECT protects psychiatric disorder Psychological distress recommendation Relieving Symptom TCM the vaccine the vaccines Torsion Traditional Chinese medicine treat treating COVID-19 Treatment Trial truncated torsion [DOI] 10.1097/MD.0000000000023874 PMC 바로가기 [Article Type] Multicenter Study
A Newcastle Disease Virus (NDV) Expressing a Membrane-Anchored Spike as a Cost-Effective Inactivated SARS-CoV-2 VaccineArticle Published on 2020-12-172022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome adjuvant animal models antigen-sparing binding coronavirus coronavirus disease COVID-19 Efficacy egg-based vaccine expressing Hamster model hamsters immunogenic inactivated Influenza virus mice mouse-adapted SARS-CoV-2 neutralizing antibody newcastle disease virus Protective reduce Safe SARS-CoV-2 SARS-CoV-2 infections spike the vaccine Vaccine vaccine production [DOI] 10.3390/vaccines8040771 PMC 바로가기 [Article Type] Article
Understanding COVID-19 vaccine demand and hesitancy: A nationwide online survey in China코로나19 백신 수요와 망설임 이해: 중국 전국 온라인 설문조사Research Article Published on 2020-12-172022-08-13 Journal: PLoS Neglected Tropical Diseases [Category] COVID-19, Medicine and Health Sciences, [키워드] 95% CI acceptance adverse event benefit China Complete conducted confidence coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines cross-sectional decrease Efficacy ENhance expressed Factors followed by Guidance HBM Health health belief Health Belief Model Health promotion Hesitancy highest IMPROVE income indicate Intention interquartile range Intervention investigated IQR majority median Perceived Perceived benefits Perception predictor preference produced proportion receive reduce reported response Result the vaccine understanding utility vaccinate vaccination vaccination intention Vaccine was determined was used [DOI] 10.1371/journal.pntd.0008961 PMC 바로가기 [Article Type] Research Article
Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates2개의 RNA 기반 Covid-19 백신 후보의 안전성 및 면역원성Clinical Trial Published on 2020-12-172022-09-12 Journal: The New England Journal of Medicine [Category] MERS, SARS, 임상, 진단, [키워드] acute respiratory syndrome added Adults age assigned BNT162b1 BNT162b2 candidate conducted convalescent serum coronavirus coronavirus disease defined disease dose dose-dependent dose-escalation doses Efficacy elicited ENCODE full-length geometric mean titer geometric mean titers Germany group healthy immunogenicity immunogenicity data incidence Infection Interim Local Multiple nucleoside-modified RNA observer-blinded of BNT162b2 Older participant Participants phase 1 trial Placebo placebo-controlled prefusion conformation Primary outcome randomization Randomly receive reported resulting Safety SARS-CoV-2 secondary outcome secreted severity spread to Support systemic reaction The United States the vaccine Trial Vaccine vaccine candidate vaccine dose [DOI] 10.1056/NEJMoa2027906 PMC 바로가기 [Article Type] Clinical Trial
Interpretative immune targets and contemporary position for vaccine development against SARS‐CoV‐2: A systematic reviewReview Published on 2020-12-172022-11-01 Journal: Journal of medical virology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Antiviral agents Candidates cause clinical trials conducted coronavirus Coronaviruses COVID‐19 COVID‐19 infection criteria develop effective evaluated Evidence explained Flow Genetic genome sequence global public health immnopathology immune immune response immunodulators implementation Laboratory literature review Novel coronavirus pandemic pathogenicity promote reported required respiratory tract SARS‐CoV‐2 SARS‐CoV‐2 infection similarity Support systematic review target the vaccine Trial Vaccine vaccine candidate Vaccine development vaccine platform Vaccines virus while World Health Organization Wuhan, China [DOI] 10.1002/jmv.26709 PMC 바로가기 [Article Type] Review
Nonhuman primate to human immunobridging to infer the protective effect of an Ebola virus vaccine candidateArticle Published on 2020-12-172022-10-04 Journal: NPJ Vaccines [Category] 비임상, [키워드] absence Analysis animal model antibodies antibody approach association binding antibody correlation disease Ebola virus Efficacy elicited glycoprotein Human immune parameter immunogenicity immunology likelihood Logistic regression analysis Mortality Neutralizing antibodies NHP outcome Phase I predicted Protective protective effect regimen survival T cell the vaccine Trial Vaccine vaccine candidate vaccine immunogenicity Vaccines [DOI] 10.1038/s41541-020-00261-9 PMC 바로가기 [Article Type] Article
Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses Research Published on 2020-12-172022-10-05 Journal: Nature Medicine [Category] SARS, 유전자 메커니즘, 임상, [키워드] Activation acute respiratory syndrome animal Anti-spike antibody Antibody Response approach AZD1222 boost booster dose Booster vaccine cell activation cellular ChAdOx1 ChAdOx1 nCoV-19 clinical trials complement coronavirus coronavirus vaccine dose doses evaluated exploratory facilitate function functional antibody responses healthy homologous humoral immunogenicity data induce Infection Interim report magnitude multifunctional natural killer neutralizing antibody neutralizing antibody titers Open-label outcome phagocytosis phase Phase 3 Prevent preventing infection priming Randomized controlled trial receive reported Safe SARS-CoV-2 vaccine serology subgroup Support T cell response the vaccine Trial vaccination Vaccine viral spike protein Viral vector Volunteer [DOI] 10.1038/s41591-020-01179-4 [Article Type] Research
A single dose of recombinant VSV-∆G-spike vaccine provides protection against SARS-CoV-2 challenge재조합 VSV-∆G-스파이크 백신의 단일 용량은 SARS-CoV-2 공격에 대한 보호를 제공합니다Article Published on 2020-12-162022-09-10 Journal: Nature Communications [Category] MERS, SARS, 변종, 진단, [키워드] abrogation alleviation Antibody Response antigenic body weight Body weight loss caused competent COVID-19 COVID-19 pandemic demonstrated dose expressing expression generate glycoprotein hamster hamsters immunization indicate lung Lungs mass immunization mice nasal turbinates Neutralizing antibodies neutralizing antibody PROTECT Protective provide replaced REPLACED BY Replication Safe SARS-CoV-2 SARS-CoV-2 neutralizing antibodies SARS-CoV-2 spike protein similarity single dose Spike protein the antibody response the spike protein the vaccine tissue damage vaccination Vaccine Vaccines Viral Viral load viral loads viral membrane VSV weight loss [DOI] 10.1038/s41467-020-20228-7 PMC 바로가기 [Article Type] Article
Biochemical and antigenic characterization of the structural proteins and their post-translational modifications in purified SARS-CoV-2 virions of an inactivated vaccine candidateOriginal Article Published on 2020-12-142022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, SARS, [키워드] Analysis anti-SARS-CoV-2 vaccines Antibody Response antibody response against antigenic antigenicity Antisera caused cleavage cleaved clinical trial convalescent convalescent serum COVID-19 pandemic demonstrated elicit facilitate FIVE form forms full-length S glycoprotein glycosylated immunization immunized immunogenic inactivated Inactivated vaccine membrane Modification modifications natural infection Neutralizing antibodies pathogenesis of SARS-CoV-2 post-translational modification protease Protein purified Quality control S glycoprotein S protein S1 and S2 S1/S2 subunit S2 subunit SARS-CoV-2 SARS-CoV-2 virion sera shown stimulated structural protein structural proteins subunit subunits the vaccine vaccination Vaccine vaccine candidate Vero virion virions [DOI] 10.1080/22221751.2020.1855945 PMC 바로가기 [Article Type] Original Article