Development of a recombinant replication-deficient rabies virus-based bivalent-vaccine against MERS-CoV and rabies virus and its humoral immunogenicity in miceResearch Article Published on 2019-10-072022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] Amino acid Analysis approved cause Cell cytoplasmic development domain ectodomain evaluated experiments expresse expression fused genetics growth humoral immunogenicity immunofluorescence Infection inoculated intraperitoneally MERS-CoV mice Middle East Neutralizing antibodies neutralizing antibody pathogenicity Rabies virus recombinant S1 and S2 Safe severe disease specific treatment spike glycoprotein subunits Symptom the S1 subunit transmembrane Vaccine Viral vector virus western blot [DOI] 10.1371/journal.pone.0223684 PMC 바로가기 [Article Type] Research Article
Assessment of naturally acquired neutralizing antibodies against rabies Lyssavirus in a subset of Nunavik’s Inuit population considered most at risk of being exposed to rabid animalsArticle Published on 2019-08-012023-06-22 Journal: Zoonoses and Public Health [Category] 조류인플루엔자, [키워드] Arctic variant Lyssavirus naturally acquired immunity Neutralizing antibodies rabies [DOI] 10.1111/zph.12561
Recombinant Chimeric Transmissible Gastroenteritis Virus (TGEV)—Porcine Epidemic Diarrhea Virus (PEDV) Virus Provides Protection against Virulent PEDVArticle Published on 2019-07-252022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] addition approach Attenuated Virus caused chimeric coronavirus defined died Effective vaccines Engineering enteric virus epidemic diarrhea evaluate expressing gastroenteritis Genome highlight humoral immune response inactivated indicated Infection Live attenuated vaccine modified live-vaccine morbidity and mortality Neutralizing antibodies outbreak PEDV protection recombinant reducing Spike protein strain TGEV tissue damage undetectable United State vaccine candidate Vaccine development virulent virus virus RNA virus titer were used [DOI] 10.3390/v11080682 PMC 바로가기 [Article Type] Article
Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Infection, Immunological Response, and Vaccine DevelopmentReview Article Published on 2019-04-072022-10-29 Journal: Journal of Immunology Research [Category] Coronavirus, MERS, [키워드] Activation Adaptive immune response adjuvant Antigen approved cellular response Combination contribute country development died Dipeptidyl peptidase-4 DPP4 effective ENhance Factor globe help highlight Host immune response infected patients infections innate immune response key factor knowledge mechanism MERS-CoV Middle East Neutralizing antibodies Pandemics Patient proinflammatory receptor respiratory respiratory syndrome coronavirus response risk Signaling Spike protein Spread therapy Treatment Vaccine Vaccine development virus WHO World Health Organization [DOI] 10.1155/2019/6491738 PMC 바로가기 [Article Type] Review Article
Evidence for an unknown agent antigenically related to the hepatitis E virus in dairy cows in the United StatesArticle Published on 2019-04-012023-06-11 Journal: Journal of medical virology [Category] E형 간염, Fulltext, [키워드] bovine cattle Hepatitis E virus (HEV) Neutralizing antibodies Seroprevalence zoonotic transmission [DOI] 10.1002/jmv.25339 PMC 바로가기
Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus FusionArticle Published on 2019-01-312023-06-14 Journal: Cell [Category] MERS, SARS, [키워드] class I fusion protein coronavirus glycoproteomics membrane fusion MERS-CoV N-linked glycosylation Neutralizing antibodies SARS-CoV spike glycoprotein [DOI] 10.1016/j.cell.2018.12.028 PMC 바로가기 [Article Type] Article
Human cytomegalovirus vaccine development: Immune responses to look into vaccine strategyReview Published on 2018-12-012024-09-04 Journal: Human vaccines & immunotherapeutics [Category] 대상포진, [키워드] Human Cytomegalovirus immune response Neutralizing antibodies T cells Vaccine [DOI] 10.1080/21645515.2017.1391433 PMC 바로가기 [Article Type] Review
Immune Priming and Long-term Persistence of Memory B Cells After Inactivated Poliovirus Vaccine in Macaque Models: Support for at least 2 Doses불활성화 폴리오바이러스 백신 접종 후 마카크 모델에서 면역 프라이밍 및 기억 B 세포의 장기 지속성: 최소 2회 접종에 대한 지지Article Published on 2018-11-152024-08-01 Journal: Clinical infectious diseases : an official publication of the Infectious [Category] 폴리오, [키워드] B-cells IPV memory Neutralizing antibodies polio priming [DOI] 10.1093/cid/ciy634 PMC 바로가기
Prospects for a MERS-CoV spike vaccineReview Published on 2018-08-092023-05-25 Journal: Expert review of vaccines [Category] Fulltext, MERS, [키워드] immune responses MERS MERS-CoV Neutralizing antibodies protection Receptor-binding domain Spike protein Vaccine [DOI] 10.1080/14760584.2018.1506702 PMC 바로가기 [Article Type] Review
Intradermal immunization with inactivated swine influenza virus and adjuvant polydi(sodium carboxylatoethylphenoxy)phosphazene (PCEP) induced humoral and cell-mediated immunity and reduced lung viral titres in pigsArticle Published on 2018-03-142023-06-24 Journal: Vaccine [Category] 신종인플루엔자, [키워드] Influenza Neutralizing antibodies protection route swine Vaccine [DOI] 10.1016/j.vaccine.2018.02.026