Neutralizing Antibody Correlates Analysis of Tetravalent Dengue Vaccine Efficacy Trials in Asia and Latin AmericaMajor Articles and Brief Reports Published on 2018-03-012024-09-04 Journal: Nanoscale [Category] 대상포진, [키워드] case cohort immune correlate of protection Neutralizing antibodies surrogate endpoint vaccine efficacy trial [DOI] 10.1093/infdis/jix609 PMC 바로가기 [Article Type] Major Articles and Brief Reports
A safe and reliable neutralization assay based on pseudovirus to measure neutralizing antibody titer against poliovirusarticle Published on 2017-12-312024-09-01 Journal: Journal of medical virology [Category] 폴리오, [키워드] Neutralizing antibodies Poliovirus pseudovirus-based neutralization assay [Article Type] article
Neutralizing Antibody Responses to Viral Infections Are Linked to the Non-classical MHC Class II Gene H2-ObArticle Published on 2017-08-152023-06-18 Journal: Immunity [Category] B형 간염, Fulltext, [키워드] Antigen presentation HLA-DO MHC locus Neutralizing antibodies positional cloning viral infections [DOI] 10.1016/j.immuni.2017.07.013 PMC 바로가기
Receptor-binding domain of MERS-CoV with optimal immunogen dosage and immunization interval protects human transgenic mice from MERS-CoV infectionResearch Paper Published on 2017-06-092023-06-15 Journal: Human vaccines & immunotherapeutics [Category] MERS, [키워드] hDPP4-transgenic mice MERS-CoV Neutralizing antibodies optimal immunization interval optimal immunogen dosage protection Receptor-binding domain [DOI] 10.1080/21645515.2017.1296994 PMC 바로가기 [Article Type] Research Paper
Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domainsArticle Published on 2017-04-102022-10-29 Journal: Nature Communications [Category] Coronavirus, [키워드] Analysis cell entry coronavirus Cryo-electron microscopy determine flexible fusion peptide high-resolution structure HKU1 host cells host tropism MERS-CoV MHV Neutralizing antibodies NL63 other coronavirus pathogenic coronavirus pre-fusion Protein Proteins RBD receptor Receptor binding Receptor binding domain reported SARS-CoV SARS-CoV S protein Sequence conservation spike glycoprotein Structure target the RBD trimeric virus [DOI] 10.1038/ncomms15092 PMC 바로가기 [Article Type] Article
Serologic Evidence for MERS-CoV Infection in Dromedary Camels, Punjab, Pakistan, 2012–2015Research Letter Published on 2017-03-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS, [키워드] Africa animal reservoir antimicrobial resistance Asia Bactrian Camels coronavirus Dromedary humans Infection livestock MERS-CoV Middle East Middle East respiratory syndrome Neutralizing antibodies one health Pakistan respiratory syndrome coronavirus RNA viruses serologic serology specific neutralizing antibody viruses zoonoses zoonotic [DOI] 10.3201/eid2303.161285 PMC 바로가기 [Article Type] Research Letter
Persistence of Antibodies against Middle East Respiratory Syndrome CoronavirusDispatch Published on 2016-10-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS, [키워드] antibody Antibody Response detectable determine Jordan MERS-CoV Middle East Middle East respiratory syndrome Neutralizing antibodies Novel coronavirus outbreak respiratory respiratory infections respiratory syndrome coronavirus serologically positive serology severe acute respiratory illness viruses [DOI] 10.3201/eid2210.160706 PMC 바로가기 [Article Type] Dispatch
Feasibility of Using Convalescent Plasma Immunotherapy for MERS-CoV Infection, Saudi ArabiaResearch Published on 2016-09-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS, [키워드] antibody Antibody titer Antibody titers assays clinical trial convalescent phase convalescent plasma convalescent-phase plasma Donor ELISA feasibility Feasibility study feasible fluorescent healthcare household contact humans identify IFA Immunotherapy indirect immunofluorescent antibody assay Infection intensive care laboratory-confirmed MERS MERS-CoV MERS-CoV infection microneutralization Middle East Middle East respiratory syndrome Middle East respiratory syndrome Coronavirus Neutralizing antibodies Patient plasma reactive respiratory infections respiratory syndrome coronavirus Saudi Arabia seroreactive serum serum sample severe disease tested Trial viruses [DOI] 10.3201/eid2209.151164 PMC 바로가기 [Article Type] Research
Host-Pathogen Coevolution and the Emergence of Broadly Neutralizing Antibodies in Chronic Infections숙주-병원체 공진화와 만성 감염에서 광범위하게 중화되는 항체의 출현Research Article Published on 2016-07-212022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adaptation adaptive immune system antibody Antigen antigens arms race binding affinities binding interaction binding interactions cellular changes in chronic chronic infection chronic infections coevolution competition condition Critical determine develop distribution driven by emergence Evolution evolutionary arms race external environment favor flexible focus Frequency Genotype HIV HIV-infected patients Host identify immune immune parameter immune population immune response infections Interaction Lineage mathematical measure molecules Mutation Neutralization assay neutralization assays neutralize Neutralizing antibodies neutralizing antibody occur Organisms parameter Pathogens Population populations provide Rapid resulting Vaccine design Viral virus viruses [DOI] 10.1371/journal.pgen.1006171 PMC 바로가기 [Article Type] Research Article
Measuring Plasmodium falciparum Erythrocyte Invasion Phenotypes Using Flow Cytometryarticle Published on 2015-12-312024-09-01 Journal: Methods in molecular biology (Clifton, N.J.) [Category] 말라리아, [키워드] blood-stage vaccine erythrocyte invasion flow cytometry malaria Merozoite Neutralizing antibodies Plasmodium [Article Type] article