Update on recommendations for the diagnosis and treatment of SARS-CoV-2 infection in childrenReview Published on 2020-08-062022-10-31 Journal: European Journal of Clinical Microbiology & Infect [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Adults caused Child children China city Committee coronavirus determine Diagnosis Diagnosis and treatment immature immune function incidence infections less New coronavirus novel Novel coronavirus Novel coronavirus infection outbreak Pneumonia progressed recommendation reduce reported SARS-CoV-2 SARS-COV-2 infection Standard susceptibility susceptible tested the disease Treatment treatment strategy Trial Update Wuhan [DOI] 10.1007/s10096-020-03973-x PMC 바로가기 [Article Type] Review
Case Report: Benign Infantile Seizures Temporally Associated With COVID-19Pediatrics Published on 2020-08-062022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] absence afebrile afebrile seizures Benign benign familial infantile epilepsy Blood case sery children Convulsion coronavirus coronavirus SARS-CoV-2 cough COVID-19 D-dimer level described disease severity dose driving electroencephalogram epilepsy Exome febrile ferritin Fever Follow-up frameshift gastroenteritis gastrointestinal complaint genetic determinant Genetic predisposition healthy children Host host response hyperimmune response Infant Infants infections magnetic resonance imaging Mild molecular mechanism mother Mutation nasal Neurological complication non-febrile seizures outcome pandemic pathogenic PCR pediatric pediatric COVID-19 performed positive Precision PRRT2 PRRT2 mutations raised repeated respiratory symptoms Respiratory tract infections SARS-CoV-2 Seizure Seizures Sequencing susceptibility Symptom throat swab triggering with COVID-19 [DOI] 10.3389/fped.2020.00507 PMC 바로가기 [Article Type] Pediatrics
Expression of SARS-CoV-2 receptor ACE2 and the protease TMPRSS2 suggests susceptibility of the human embryo in the first trimester1001 Published on 2020-08-052022-10-29 Journal: Open Biology [Category] COVID-19, MERS, [키워드] ACE2 ACE2 receptor advanced age Affect Blood cleave co-expression Complication complications concerning determine develop Effect Embryo expression expression pattern facilitate fetal Health indicate infected with SARS-CoV-2 Infection obesity other organ placental potential risk Pregnancy protease question raise receptor receptor ACE2 required Respiratory disease risk factor SARS-CoV-2 SARS-CoV-2 receptor stages susceptibility the SARS-CoV-2 the SARS-CoV-2 virus tissue TMPRSS2 Transmission viral spike protein while [DOI] 10.1098/rsob.200162 PMC 바로가기 [Article Type] 1001
Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort StudyArticle Published on 2020-08-052022-10-04 Journal: Cell Reports Medicine [Category] MERS, 유전자 메커니즘, [키워드] adjusted odds ratio Bacille Calmette-Guérin bacille Calmette-Guérin BCG BCG vaccination Cohort coronavirus disease COVID-19 COVID-19 outbreak COVID-19 pandemic decrease disease symptom Effectiveness extreme fatigue healthy volunteer hyperinflammation Immunity incidence individual induce innate immune responses Innate immunity Netherlands non-specific effects off-target effects prevention of COVID-19 Prospective raised randomized clinical trial randomized trial recent reduce reduced reducing Respiratory tract infections retrospective cohort study Safe Safety SARS-CoV-2 SARS-COV-2 infection severity Sickness susceptibility Symptom trained immunity Trial [DOI] 10.1016/j.xcrm.2020.100073 PMC 바로가기 [Article Type] Article
Management of epigenomic networks entailed in coronavirus infections and COVID-19Review Published on 2020-08-052022-10-31 Journal: Clinical Epigenetics [Category] COVID-19, MERS, [키워드] acute respiratory syndrome Antiviral approach approved clinical trials clinically combination therapy coronavirus Coronavirus disease 2019 Coronavirus infection Coronavirus infections coronavirus pathogenesis COVID-19 COVID-19 disease CoVs death deaths drug effective emerging disease Epigenetic epigenomic Focusing Gene Expression genomic immune system increase in indicated infected case Inflammation Inflammatory marker MERS-CoV Middle East molecular mechanism Mutation outcome pathogen Patient Recombination Regulation Replication respiratory syndrome coronavirus respiratory tract SARS-CoV SARS-CoV-2 single-stranded RNA virus susceptibility the cytokine storm therapy Transcription viral entry viral replication virus Virus-host interaction worldwide pandemic [DOI] 10.1186/s13148-020-00912-7 PMC 바로가기 [Article Type] Review
Population risk factors for COVID-19 deaths in Nigeria at sub-national levelResearch Published on 2020-08-042022-10-28 Journal: The Pan African Medical Journal [Category] COVID-19, MERS, SARS, [키워드] affected Africa African age Analysis analyzed BCG BCG vaccination CDC clinical risk factor Cluster conducted confirmed case confirmed COVID-19 case correlated country Coverage COVID-19 death Delta Epidemiology examined Factor GDP Generalized linear model greater HIV incidence include indicate Lagos Mortality mortality rate multivariate Nigeria Population Prevalence Region Result retrieved risk factor Risk factors river SARS-CoV-2 smoking Sociodemographic factor state Statistics susceptibility University of Washington [DOI] 10.11604/pamj.supp.2020.35.131.25258 PMC 바로가기 [Article Type] Research
Tobacco, but Not Nicotine and Flavor-Less Electronic Cigarettes, Induces ACE2 and Immune DysregulationArticle Published on 2020-07-312022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] ACE2 ASC caused CCL20 CCL5 CCR1 cellular receptor chemokine COVID-19 COVID-19 infection COVID-19 pandemic CXCL1 CXCL2 CXCL8 Cytokine dysregulation Cytokine storm Cytokines dataset demonstrated dysregulation Electronic cigarettes Epidemics exacerbate Genes hallmark IL-1B immune response implicated independent Infection Inflammasome inflammasome activation inflammasomes Inflammation Nicotine NOD2 outcome overlap pathway pro-inflammatory cytokine Release risk RNA expression SARS-CoV-2 severe cases smoker Smokers smoking susceptibility the SARS-CoV-2 virus Tobacco upregulate upregulated upregulation vaping [DOI] 10.3390/ijms21155513 PMC 바로가기 [Article Type] Article
Genetic variability in the expression of the SARS-CoV-2 host cell entry factors across populationsArticle Published on 2020-07-312022-10-31 Journal: Genes and Immunity [Category] COVID-19, MERS, [키워드] ACE2 African angiotensin-converting enzyme 2 applied COVID-19 disease entry of SARS-CoV-2 eQTL expression Factor functional Genetic genetic determinant Genetic predisposition glycoprotein host cell host cell membranes host genetics individual individuals inter-individual lower expression mechanism Population populations Quantitative receptor SARS-CoV-2 serine protease TMPRSS2 severity of COVID-19 susceptibility the SARS-CoV-2 TMPRSS2 TMPRSS2 expression Variability viral entry viral spike [DOI] 10.1038/s41435-020-0107-7 PMC 바로가기 [Article Type] Article
The macroecology of the COVID-19 pandemic in the AnthropoceneResearch Article Published on 2020-07-302022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome addition affecting age analysed Anthropocene association Care cause Characteristics confounding factor Contact coronavirus coronavirus disease country COVID-19 COVID-19 case COVID-19 cases COVID-19 outbreak COVID-19 pandemic database death deaths disease Effect explain Factor geographic location growth Health help hypothese Infection less Migration pandemic positive proportion recorded responsible Spread susceptibility tested the mean threshold virus [DOI] 10.1371/journal.pone.0236856 PMC 바로가기 [Article Type] Research Article
Transferrin receptor 1 levels at the cell surface influence the susceptibility of newborn piglets to PEDV infectionResearch Article Published on 2020-07-302022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] activate Ammonium antibody Caco-2 caused Cell Clustering deficiency epidemic diarrhea expression Extracellular HEK 293T impair in vitro in vivo infect Infection infections inhibited interact intestinal intestinal epithelial cell intestinal epithelial cells iron accumulation iron deficiency mechanism Newborn Older over-expressed PEDV Phosphorylation promote provide receptor reduce reveal S1 protein susceptibility susceptible therapy These data tissue Transferrin Treatment tyrosine virus was increased [DOI] 10.1371/journal.ppat.1008682 PMC 바로가기 [Article Type] Research Article