the vaccine

[키워드] acute respiratory syndrome addition Adults adverse event adverse events anti-Spike IgG Antigen assigned CD4+ T-cell Coalition composed convalescent serum coronavirus cytokine doses drug elicited ELISA enzyme-linked immunosorbent evaluate exceeded Fever food full-length SARS-CoV-2 geometric healthy IgG immune response immune responses initiated intramuscular injections Laboratory majority Matrix-M1 adjuvant microneutralization Mild nanoparticle neutralization NVX-CoV2373 outcome participant Participants Patient performed phase Placebo placebo-controlled primary analysis Primary outcome Protein randomization Randomized receive recombinant regimen response Result Safe SARS-CoV-2 secondary Serious Adverse Event serum chemistry severe adverse events short duration spike spike glycoprotein staining symptomatic symptomatic COVID-19 T helper T-cell Response Th1 Th1 phenotype the vaccine Toxicity Trial trimeric vaccination Vaccine wild-type virus
[DOI] 10.1056/NEJMoa2026920 PMC 바로가기 [Article Type] Clinical Trial