COVID-IRS: A novel predictive score for risk of invasive mechanical ventilation in patients with COVID-19COVID-IRS: COVID-19 환자의 침습적 기계 환기 위험에 대한 새로운 예측 점수Research Article Published on 2021-04-052022-09-10 Journal: PLoS ONE [Category] MERS, 바이오마커, [키워드] Acute respiratory failure administration Admission adverse outcome adverse outcomes applicability AUC Cohort cohort study coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients death develop diagnosed disease estimate FiO2 health-care IL-6 IMV interleukin interleukin-6 Invasive mechanical ventilation lactic dehydrogenase LDH mechanical ventilation neutrophil/lymphocyte ratio NLR objective participant Patient patients with COVID-19 populations predict Predictive resources Respiratory failure respiratory rate Result retrospective cohort study risk SpO2 SpO2/FiO2 systemic disease validation cohort variable variables [DOI] 10.1371/journal.pone.0248357 PMC 바로가기 [Article Type] Research Article
Global Sex Disparity of COVID-19: A Descriptive Review of Sex Hormones and Consideration for the Potential Therapeutic Use of Hormone Replacement Therapy in Older AdultsReview Published on 2021-04-012022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] Adults adverse effect adverse outcomes affected age and sex approved Care clinical trial confirmed case Coronavirus-2 COVID-19 death disparity drug elderly patients Evidence FDA food healthcare hormone hospitalizations hospitals ICU admissions immune system knowledge male Older Older adults outcome pandemic Patient performed positive Potential progesterone reducing replacement review SARS-CoV-2 SARS-COV-2 infection Sex sex hormone Sex hormones sexual disparity significantly stages Steroids therapeutic option treating COVID-19 vaccine for COVID-19 [DOI] 10.14336/AD.2020.1211 PMC 바로가기 [Article Type] Review
Compassionate use of remdesivir in children with COVID-19COVID-19에 걸린 어린이를 위한 렘데시비르의 자비로운 사용Observational Study Published on 2021-04-012022-08-31 Journal: European journal of pediatrics [Category] 신약개발, 임상, 치료제, [키워드] adverse events adverse outcome adverse outcomes age approved Bacterial sepsis children children with COVID-19 clinical Clinical outcome clinical status clinical trials Cohort complex Complication complications conducted COVID-19 COVID-19 cases COVID-19 disease Critically ill death demonstrated died drug effective Efficacy eight first COVID-19 symptom Infant Infants intensive care unit IQR Medical conditions multicenter observational study multicentre observational study Older on children one patient pandemic Patient patients Pediatric patients pharmacokinetics RDV reached receiving Remdesivir reported SARS-CoV-2 Sepsis severe cases severe COVID-19 disease severe disease Spain the patient therapy Tolerability treat Treatment Trial with COVID-19 [DOI] 10.1007/s00431-020-03876-1 PMC 바로가기 [Article Type] Observational Study
Multicenter Assessment of CT Pneumonia Analysis Prototype for Predicting Disease Severity and Patient OutcomeObservational Study Published on 2021-04-012022-10-05 Journal: Journal of digital imaging [Category] SARS, 임상, [키워드] 95% CI 95% confidence interval Admission adverse outcomes age analyses analyses of variance assessment AUC Chest CT clinical information comorbid conditions COVID-19 COVID-19 pneumonia CT death deep deep learning disease severity feature Final Frequency Gender help ICU ICU admission intensive care involved Iran Laboratory Logistic regression lung lung lobe lung volumes males Massachusetts General Hospital mechanical ventilation moderate motion Motion artifacts multicenter no significant difference outcome Patient Patient outcome. performed Pneumonia processed prototype Quantitative radiologist recorded severity Severity Score Siemens Healthineers Standard deviation tertiary care hospital Thoracic Volume [DOI] 10.1007/s10278-021-00430-9 PMC 바로가기 [Article Type] Observational Study
Potential Drug Interactions of Repurposed COVID-19 Drugs with Lung Cancer Pharmacotherapies재활용된 COVID-19 약물과 폐암 약물 요법의 잠재적 약물 상호 작용Review Published on 2021-04-012022-08-31 Journal: Archives of medical research [Category] MERS, SARS, 신약개발, 치료제, [키워드] adverse outcomes anti-cancer treatment Azithromycin cancer patient Care ceftriaxone Chemotherapy Chloroquine Comorbidity Complication concomitant treatment concomitant treatments COVID-19 COVID-19 infection COVID-19 pandemic Dexamethasone dissemination drug Drug interactions drug-drug interaction Drug-drug interactions Famotidine Favipiravir Healthcare professional healthcare professionals history of smoking Hydroxychloroquine identification identify Immunosuppression information kinase inhibitors Lopinavir Lopinavir/ritonavir lung cancer lung cancer patient lung cancer patients malignancy management medication medications occur oseltamivir outcome Patient pharmacotherapy Potential Prophylactic proportion QT prolongation rationale receiving recent Remdesivir reported Reporting Repurposed drug ribavirin risk risk factor Ritonavir sarilumab severity smoking Tocilizumab tyrosine tyrosine kinase inhibitors umifenovir with COVID-19 [DOI] 10.1016/j.arcmed.2020.11.006 PMC 바로가기 [Article Type] Review
Association between red blood cell distribution width and mortality and severity among patients with COVID-19: A systematic review and meta-analysisCOVID-19 환자의 적혈구 분포 폭과 사망률 및 중증도의 연관성: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-04-012022-09-11 Journal: Journal of medical virology [Category] MERS, SARS, 바이오마커, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission adverse outcome adverse outcomes association Biomarker Biomarkers Blood blood cell Cell Clinical outcome clinical outcomes Control coronavirus COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity died disease severity disease severity of COVID-19 distribution erythrocyte erythrocyte indices Evidence inception less mean differences Meta-analysis Mortality on admission pathophysiology Patient patients hospitalized patients who survived plasma Prognosis red blood cell red blood cell distribution width Research respiratory severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe symptoms severely ill COVID-19 patients severity subject Symptom systematic review was performed with COVID-19 [DOI] 10.1002/jmv.26797 PMC 바로가기 [Article Type] Meta-Analysis
COVID-19 and cancer registries: learning from the first peak of the SARS-CoV-2 pandemicReview Article Published on 2021-03-252022-10-28 Journal: British Journal of Cancer [Category] COVID-19, SARS, [키워드] adverse outcome adverse outcomes age anti-cancer treatment association Cancer cancer patient Care caused Chemotherapy China common COVID-19 death disease Evidence feature First wave identify Immunotherapy include increased risk indicated Infection International lung cancer Male sex Mortality MOST National number of comorbidity oncology outcome pandemic Patient patients Patients with cancer performance status predict Probability recent recruitment risk risk factor SACT smoking solid cancer the SARS-CoV-2 the timing therapy trajectory viral infection [DOI] 10.1038/s41416-021-01324-x PMC 바로가기 [Article Type] Review Article
Current trends and geographical differences in therapeutic profile and outcomes of COVID-19 among pregnant women – a systematic review and meta-analysis임산부의 COVID-19 치료 프로파일 및 결과의 현재 동향 및 지리적 차이 - 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-03-242022-09-10 Journal: BMC Pregnancy and Childbirth [Category] SARS, 치료제, [키워드] administration adverse outcome adverse outcomes Adverse pregnancy outcomes Analysis analyzed Antibiotics Antiviral antivirals article Asian assessment average Case report case sery Cesarean section clinical care clinical outcomes coronavirus coronavirus disease COVID-19 cumulative current disease effective eligible European except for highest Hospital stay Hydroxychloroquine ICU admission immunosuppressants imperative IMPROVE lack Latin Maternal death mechanical ventilation meta-analyses Meta-analysis nine outcome outcomes oxygen oxygen support Oxygen therapy patients performed plasma Pregnancy pregnant women Preterm birth proportion proportions reported Result risk stratification severe cases supplementary material systematic review therapeutic Therapeutics therapy Treatment treatments for COVID-19 was performed with COVID-19 [DOI] 10.1186/s12884-021-03685-w PMC 바로가기 [Article Type] Meta-Analysis
Implications of SARS-COV-2 infection in the diagnosis and management of the pediatric gastrointestinal diseaseReview Published on 2021-03-242022-10-29 Journal: Italian Journal of Pediatrics [Category] COVID-19, SARS, [키워드] 2019 coronavirus disease ACE2 acute respiratory syndrome adverse outcomes approach benefit Care changed children chronic diarrhea chronic disease chronic liver disease clinical implication coronavirus COVID-19 Diagnosis digestive Digestive endoscopy disease Diseases disorder Follow-up visit functional Functional gastrointestinal disorders gastrointestinal disease gastrointestinal symptoms high risk IBD Immunosuppression infected children Infection Inflammatory bowel disease Liver disease management pandemic era parent Patient pediatric pediatrics Personal protective equipment protocol Psychological regimen risk risk factor SARS-CoV-2 SARS-CoV-2 vaccination social distancing therapeutic Treatment Viral transmission [DOI] 10.1186/s13052-021-01020-9 PMC 바로가기 [Article Type] Review
Clinical Features and Risk Factors for In-Hospital Mortality From COVID-19 Infection at a Tertiary Care Medical Center, at the Onset of the US COVID-19 PandemicOriginal Research Published on 2021-03-242022-10-29 Journal: Journal of Intensive Care Medicine [Category] COVID-19, MERS, [키워드] Admission adverse outcomes age albumin AST benefit Care center clinical Clinical research clinical risk factor Cohort collected comorbid condition Comorbidity conducted congestive heart failure COVID-19 death Dementia Detroit Diagnosis died Factor fatal COVID-19 Fatality rate greater help hospital Hospital mortality hospitalized patients identify in-hospital mortality independent index Infection infections information initial Inpatient Intervention Laboratory laboratory biomarker laboratory data lymphocytopenia male malignancy management marker mitigate Mortality multivariable analysis Nasopharyngeal swab obesity observation Older Older age Onset pandemic Patient patients died patients with COVID-19 positive Primary outcome qSOFA remained retrospective cohort study risk factor RT-PCR significantly single-center Tertiary understanding vital signs WBC with COVID-19 [DOI] 10.1177/08850666211001799 PMC 바로가기 [Article Type] Original Research