Induction of SARS-CoV-2-Specific IgG and IgA in Serum and Milk with Different SARS-CoV-2 Vaccines in Breastfeeding Women: A Cross-Sectional Study in Northern Spain모유 수유 여성에서 다양한 SARS-CoV-2 백신을 사용한 혈청 및 우유에서 SARS-CoV-2-특이적 IgG 및 IgA 유도: 스페인 북부의 횡단면 연구Observational Study Published on 2021-08-212022-09-12 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, 임상, 진단, [키워드] addition Administered Adverse reaction Adverse reactions Analysing anti-S1 IgG antibody anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody anti-SARS-CoV-2 vaccine anti-SARS-CoV-2 vaccines antibodies antibody antigens BNT162b2 breast milk Breastfeeding breastfeeding women ChAdOx1 ChAdOx1-S clinical trial clinical trials conducted COVID-19 vaccine dose event Fever general malaise had no headache IgA IgA antibodies IgG IgG antibodies IgG isotype antibodies IgG isotype antibody induction Infant isotype levels of antibody malaise maternal immunity mean value milk mother mRNA mRNA-1273 neonatal immunity observational study of BNT162b2 offer response to vaccination SARS-CoV-2 SARS-CoV-2 antigens SARS-CoV-2 protein serum significant difference significant differences significantly higher single dose Spain the SARS-CoV-2 vaccination Vaccine variable were excluded women [DOI] 10.3390/ijerph18168831 PMC 바로가기 [Article Type] Observational Study
Petechiae and Desquamation of Fingers Following Immunization With BTN162b2 Messenger RNA (mRNA) COVID-19 VaccineFamily/General Practice Published on 2021-08-032022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Adverse reaction Adverse reactions caused Clinical course coronavirus coronavirus disease COVID-19 COVID-19 vaccine COVID19 death described desquamation driving effective vaccine facial female finger imperative messenger mRNA occurred pandemic Patient petechiae Pfizer-BioNTech Pfizer-BioNTech vaccine Rash receiving RNA SARS-CoV-2 second dose Side effect the United State the vaccine Treatment vaccination Vaccine variant virus while [DOI] 10.7759/cureus.16858 PMC 바로가기 [Article Type] Family/General Practice
Acute myocarditis following Comirnaty vaccination in a healthy man with previous SARS-CoV-2 infectionCase Report Published on 2021-08-022022-10-28 Journal: Radiology Case Reports [Category] COVID-19, [키워드] Abnormalities Acute myocarditis Adverse reaction benefit BNT162b2 cardiac children complications COVID-19 doses Echocardiogram elevated first dose Health authority healthy Infection lower risk men Mild Moderna mRNA mRNA vaccines mRNA-1273 myocarditis occur of BNT162b2 Pain Pfizer-BioNTech reactogenicity reported resonance risk SARS-COV-2 infection second dose Side effect significantly Surveillance sweating Tachycardia the patient therapy Trial troponin vaccination Vaccine X-ray younger people [DOI] 10.1016/j.radcr.2021.07.082 PMC 바로가기 [Article Type] Case Report
Safety and immunogenicity of COVID-19 vaccination in patients with non-alcoholic fatty liver disease (CHESS2101): A multicenter study비알코올성 지방간 질환 환자에서 코로나19 예방접종의 안전성과 면역원성(CHESS2101): 다기관 연구Multicenter Study Published on 2021-08-012022-09-12 Journal: Journal of hepatology [Category] MERS, SARS, 진단, [키워드] Adverse reaction appear China concern coronavirus disease COVID-19 COVID-19 vaccination COVID-19 vaccine disease dose Efficacy Fatty liver headache inactivated Inactivated vaccine incidence injection injection site pain IQR male median median age Median BMI Mild multicenter NAFLD neutralizing antibody Neutralizing antibody response Neutralizing antibody titer outcome Pain Patient primary immunogenicity progressed raised response Safe Safety SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine vaccination Vaccine were recorded [DOI] 10.1016/j.jhep.2021.04.026 PMC 바로가기 [Article Type] Multicenter Study
Vaccinations and Autoimmune DiseasesReview Published on 2021-07-222022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] adverse event Adverse reaction associations Autoimmune diseases Autoimmunity caused characterized correlation demonstrated disorder dysregulation effective Epidemiological study explain flu vaccine Guillain-Barré syndrome heterogeneous group Hypothesis immune system immunization measure mechanism MMR occur occurred pandemic public health risk Safe SARS-CoV2 SARS-CoV2 vaccines Support syndrome Systemic autoimmune diseases the vaccine thrombocytopenia triggering vaccination Vaccine vaccine-induced immune thrombotic thrombocytopenia Vaccines [DOI] 10.3390/vaccines9080815 PMC 바로가기 [Article Type] Review
Safety and immunogenicity of a recombinant COVID-19 vaccine (Sf9 cells) in healthy population aged 18 years or older: two single-center, randomised, double-blind, placebo-controlled, phase 1 and phase 2 trials18 세 이상의 건강한 인구에서 재조합 코비드 -19 백신 (SF9 세포)의 안전성 및 면역 원성 : 2 개의 단일 센터, 무작위, 이중 맹검, 위약 대조, 1 상 및 2 상 시험의 안전성 및 면역 원성Clinical Trial Published on 2021-07-152022-08-13 Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, SARS, 임상, [키워드] (phase 1 (phase 2 (phase 2) 95% CI Adverse reaction Adverse reactions antibody assigned candidate vaccine China cough COVID-19 vaccine COVID-19 vaccines dose double-blind Eligible participants ELISA enrolled fatigue Fever GMT GMTs headache healthy High dose high dose vaccine highest immune response immune responses immunogenicity injection live SARS-CoV-2 low dose vaccine Neutralising Antibodies neutralising antibody Older Pain participant peaked Phase 1 phase 1 trial Phase 2 phase 2 trial Placebo placebo-controlled problem randomised Randomly receive recombinant COVID-19 vaccine Safe Safety schedule Sf9 cells single-center sore throat Specific Specific T-cell response T-cell Response Tolerability Trial trials vaccination Vaccine Vaccines [DOI] 10.1038/s41392-021-00692-3 PMC 바로가기 [Article Type] Clinical Trial
Serologic Status and Toxic Effects of the SARS-CoV-2 BNT162b2 Vaccine in Patients Undergoing Treatment for CancerResearch Published on 2021-07-082022-10-30 Journal: JAMA Oncology [Category] COVID-19, [키워드] 95% CI Administered administration adverse effect adverse event Adverse reaction age antibody production anticancer appear blood cell counts BNT162b2 BNT162b2 vaccine Campus Cancer Chemotherapy Cohort cohort study collected conducted Control controls COVID-19 case COVID-19 infection determine division Effect Efficacy Efficacy and safety electronic medical record enrolled evaluate evaluated exposure finding first dose Future Health care worker healthy healthy individuals high-risk population IgG Importance incidence initiated leukopenia liver enzyme measure men objective occur occurred Odds ratio of BNT162b2 participant Patient patients Patients with cancer Phase 3 Point populations rate ratio reached real-world data receiving reduced Regulatory Relevance reported Result Safe SARS-CoV-2 BNT162b2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine second dose Seroconversion serologic seronegative patients Seronegativity seropositive serum serum sample setting Sociodemographic characteristics status Testing the healthy the patient the SARS-CoV-2 the vaccine therapy toxic Treatment Trial trials vaccination Vaccine vaccine dose was used [DOI] 10.1001/jamaoncol.2021.2675 PMC 바로가기 [Article Type] Research
Purpuric Skin Rash in a Patient Undergoing Pfizer-BioNTech COVID-19 Vaccination: Histological Evaluation and PerspectivesCommunication Published on 2021-07-082022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] adverse events Adverse reaction Affect affected Brain confirmed case COVID-19 COVID-19 pandemic deaths described histopathological less literature review Lungs oral steroid organs Patient Pfizer-BioNTech Placenta purpuric Rash rashe SARS-CoV-2 SARS-CoV-2 vaccine skin skin rashes therapy Vaccines vessels was performed [DOI] 10.3390/vaccines9070760 PMC 바로가기 [Article Type] Communication
Evaluation of the efficacy and safety of recombinant erythropoietin on the improvement of hospitalised COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial입원한 COVID-19 환자의 개선에 대한 재조합 에리트로포이에틴의 효능 및 안전성 평가: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-07-062022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 48 hours Adverse reaction Adverse reactions age approved Arm Bandar Abbas Blinding block randomization blood pressure Care checked chronic lung disease clinical clinical symptom clinical trial clinical trials Committee company comparator Patients composite endpoint control group Controlled clinical trial controls Coronary heart disease COVID-19 COVID-19 patient COVID-19 patients CRP Deep vein Deep vein thrombosis diabetes Diabetes Mellitus Diastolic blood pressure dissemination distilled water Efficacy and safety element End-stage renal disease endogenous enoxaparin erythropoietin ethics committee evaluate evaluate the effect excluded exclusion criteria expected Haemoglobin Health Health care heart disease hospitalised hospitalised COVID-19 patients Hypoxemia immune system infiltration injection intervals Intervention intervention group investigator Iran Laboratory test Laboratory tests LDH Liver disease Local Lung disease lung field lung infiltration lymphocyte Lymphocyte count lymphopenia Medical Science Medical Sciences medication minute number objective oral contraceptive outcome oxygen oxygen partial pressure oxygen saturation parallel-group partial pressure participant Patient PCR performed pharmaceutical Pharmaceutical Company Phase 2 Placebo positive Prevent principal investigator protocol randomised randomised controlled trial Randomized Randomly receive recombinant erythropoietin recruitment Registered registry renal disease reported respiratory respiratory rate Sample size saturation severe COVID-19 symptom severe COVID-19 symptoms Side effect Side effects Standard Standard of care status sterile water Study protocol subcutaneous injection subject supplementary material Systolic blood pressure tachypnea technology the ethics committee thrombosis title Treatment protocol treatment protocols Trial registration university vital signs water water for injection weakened immune system website [DOI] 10.1186/s13063-021-05363-w PMC 바로가기 [Article Type] Letter
Effect of 2 Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults: A Randomized Clinical TrialClinical Trial Published on 2021-07-062022-10-05 Journal: JAMA [Category] 임상, [키워드] 95% CI adverse event Adverse reaction age aluminum Analysis Bahrain Chinese clinical contributed COVID-19 COVID-19 vaccines Data collection data set dose doses double-blind Effect effective vaccine Efficacy efficacy analysis Enrollment evaluate Evidence Final Follow-up group groups had no hydroxide inactivated Inactivated vaccine injection interim analysis Intramuscular injection laboratory-confirmed median men occurred Older outcome participant per 1000 person-years phase 3 trial Primary outcome randomization Randomized randomized clinical trial reaction receive reduced resulting risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine second dose secondary outcome Serious Adverse Event Severe case severe COVID-19 significantly strain symptomatic the vaccine Treatment United Arab Emirate Vaccine vaccine dose was collected [DOI] 10.1001/jama.2021.8565 PMC 바로가기 [Article Type] Clinical Trial