antibody levels – Page 14 – Communicable Diseases Research

Antibody Response to the BNT162b2 mRNA COVID-19 Vaccine in Subjects with Prior SARS-CoV-2 Infection

SARS-CoV-2 감염 이전에 BNT162b2 mRNA COVID-19 백신에 대한 항체 반응

Clinical Trial

Published on 2021-03-052022-08-13
Journal: Viruses [Category] SARS, 임상, 진단,

Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection

경도 SARS-CoV-2 감염에 대한 항체 반응의 이질성 및 혈청 역전의 시계열 분석 및 기계론적 모델링

Research Paper

Published on 2021-03-022022-09-11
Journal: EBioMedicine [Category] SARS, 진단, 치료법,

[키워드] Analysis Anti-S1 antibody antibody levels antibody production Antibody Response antibody titres assays Asymptomatic Blood blood sampling changes in clearance Comparisons correlated deaths evaluate Extended faster finding Follow-up funding greater healthcare worker heterogeneity heterogeneous Humoral immunity identify IgG Infection infections London Longevity Longitudinal studies longitudinal study Mathematical modelling mechanism median Mild mild infection mild SARS-CoV-2 infection neutralising antibody titre NIHR participant PCR peak population level positive production rate prospective cohort study protective humoral immunity pseudovirus pseudovirus neutralizing antibody recruited reduction in reductions in required response Roche S1 domain SARS-CoV-2 SARS-CoV-2 epidemic SARS-COV-2 infection SARS-CoV-2, Serology, Mathematical modelling, Sero-reversion semi-quantitative serological analysis serological response serology sustained Symptom time transition Viral viral nucleocapsid protein viral spike was performed Wellcome Trust
[DOI] 10.1016/j.ebiom.2021.103259 PMC 바로가기 [Article Type] Research Paper

Evolution of antibody immunity to SARS-CoV-2

SARS-CoV-2에 대한 항체 면역의 진화

Article

Published on 2021-03-012022-09-11
Journal: Nature [Category] Fulltext, SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus affected Analysis animal model animal models antibody antibody immunity antibody level antibody levels Antigen assays asymptomatic individual Asymptomatic individuals B cells biopsy bowel Cell Cohort coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 death decrease Evolution examined Express greater humoral Humoral response IgA IgG antibodies IgM and IgG immunofluorescence immunoreactivity individual individuals Infection infection with SARS-CoV-2 intestinal intestinal biopsies knowledge less levels of antibody memory memory B memory B cell memory B cells memory response Neutralizing activity nucleic acids PCR persistence plasma PROTECT pseudotype virus RBD RBD mutation RBD mutations RBD-specific memory B cells Receptor-binding domain Reinfection required respiratory responsible SARS-CoV-2 SARS-CoV-2 nucleic acid severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly Spike protein the antibody the receptor-binding domain the spike protein titre titres
[DOI] 10.1038/s41586-021-03207-w PMC 바로가기 [Article Type] Article

The characteristics of 527 discharged COVID-19 patients undergoing long-term follow-up in China

중국에서 장기 추적 관찰 중인 코로나19 퇴원 환자 527명의 특징

Article

Published on 2021-03-012022-09-11
Journal: International Journal of Infectious Diseases [Category] SARS, 치료기술,

[키워드] age anal swabs antibodies antibody Antibody detection antibody levels average basic Characteristics China coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient discharge discharged discharged patient discharged patients enrolled feature Features Follow-up group groups hospitalized COVID-19 patient imaging imaging features implication improvement Juvenile Long-term follow-up management negative nucleic acid Nucleic acid detection outbreak Patient positive Recovered COVID-19 patients Reinfection respiratory Respiratory samples RNA SARS-CoV-2 SARS-CoV-2 antibodies Stool stool samples susceptible
[DOI] 10.1016/j.ijid.2021.01.064 PMC 바로가기 [Article Type] Article

Longitudinal follow-up of IgG anti-nucleocapsid antibodies in SARS-CoV-2 infected patients up to eight months after infection

SARS-CoV-2 감염 환자에서 감염 후 최대 8개월까지 IgG 항-뉴클레오캡시드 항체의 종단 추적

Multicenter Study

Published on 2021-03-012022-09-11
Journal: Journal of Clinical Virology [Category] MERS, SARS, 진단, 치료법,

[키워드] Abbott anti-N IgG anti-nucleocapsid antibody antibodies antibody antibody level antibody levels Architect collected coronavirus COVID-19 Critical decrease develop eight first positive Follow-up hospitals IgG IgG antibodies IgG antibody immunoassay Immunoglobulin Immunoglobulin G Infection longitudinal Longitudinal studies Mild mild patient mild patients moderate MOST patients PCR PCR-confirmed positive remained retrospective SARS-CoV-2 SARS-CoV-2 infected patient seroconverted seronegative severe COVID-19 severe COVID-19 patients Severe patient severe patients shown significantly higher significantly lower steadily decreased symptom onset university was performed were measured windows within 6 months
[DOI] 10.1016/j.jcv.2021.104765 PMC 바로가기 [Article Type] Multicenter Study

IgM and IgG Profiles Reveal Peculiar Features of Humoral Immunity Response to SARS-CoV-2 Infection

IgM 및 IgG 프로필은 SARS-CoV-2 감염에 대한 체액 면역 반응의 독특한 특징을 보여줍니다

Article

Published on 2021-02-012022-09-12
Journal: International Journal of Environmental Research an [Category] MERS, 진단,

[키워드] age antibodies antibody antibody levels Asymptomatic Characteristics chemiluminescence immunoassay clinical status Comorbidities Concentration coronavirus disease Coronavirus disease 2019 COVID-19 Critical healthcare humoral Humoral immunity Humoral response IgG IgG titer IgG titers IgM IgM and IgG independent individuals information inter-individual mechanism Mild Patient patients pauci-symptomatic peaked persistence positive presence of comorbidity profile response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 swab severe symptom Sex significantly higher subject Swab test symptom onset Symptoms Variability
[DOI] 10.3390/ijerph18031318 PMC 바로가기 [Article Type] Article

Interplay of Antibody and Cytokine Production Reveals CXCL13 as a Potential Novel Biomarker of Lethal SARS-CoV-2 Infection

항체와 사이토카인 생산의 상호작용으로 CXCL13이 치명적인 SARS-CoV-2 감염의 잠재적인 신규 바이오마커로 밝혀짐

Research Article

Published on 2021-01-202022-09-10
Journal: mSphere [Category] 바이오마커, 진단, 치료법,

[키워드] Activation age Alpha Analysis analyzed anti-SARS-CoV-2 antibody antibodies antibody antibody level antibody levels Antigen antigens B cell Biomarker Blood blood type chemokine chemokine CXCL13 chemotactic marker chemotactic markers Course COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients COVID-19 virus CXCL13 cytokine Cytokine analysis cytokine response Cytokines develop disease disease severity elevated Eotaxin exhibited explain gamma interferon Germinal center healthy individuals help identify IFN-γ IL-12 IL-18 IL-2 IL-4 IL-6 IL-8 immune immune response immune system Immunity immunological Immunological response Increases increases in Infection information interferon interleukin interleukin 6 involved IP-10 knowledge lethal magnitude majority marker maturation MIP-1α Necrosis novel nucleocapsid outcomes Patient patient mortality patients who survived populations Potential produced Production proinflammatory Protein provide RANTES RBD Receptor binding domain S1 subunit SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-CoV-2 immunity SARS-CoV-2 pandemic SARS-CoV-2 patient SARS-CoV-2 patients severe COVID-19 Sex significant level specificity specimens systemic immune response TNF-α Tumor tumor necrosis tumor necrosis factor tumor necrosis factor alpha Variation Viral Viral proteins
[DOI] 10.1128/mSphere.01324-20 PMC 바로가기 [Article Type] Research Article

Sensitive detection of total anti-Spike antibodies and isotype switching in asymptomatic and symptomatic individuals with COVID-19

COVID-19를 가진 무증상 및 증상이 있는 개인에서 총 항-스파이크 항체 및 이소타입 전환의 민감한 감지

Article

Published on 2021-01-162022-09-10
Journal: Cell Reports Medicine [Category] MERS, 진단, 치료기술,

[키워드] acquisition acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibodies antibody antibody levels Antibody Response Asymptomatic asymptomatic individual Asymptomatic individuals asymptomatic infection asymptomatic infections can be used coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cytometry detect develop dominant Early detection Flow flow cytometry IgA IgG IgG subclasses IgG1 IgM Immunoglobulin immunoglobulin M individual individuals with COVID-19 Infection infections isotype switching limit plasma sample plasma samples Protein respiratory S protein SARS-CoV-2 sensitive serological serological analysis severe acute respiratory syndrome Coronavirus significantly higher specific antibodies specific antibody specific IgM Spread symptomatic symptomatic and asymptomatic symptomatic individual symptomatic individuals with COVID-19
[DOI] 10.1016/j.xcrm.2021.100193 PMC 바로가기 [Article Type] Article

Dynamics of Neutralizing Antibody Titers in the Months After Severe Acute Respiratory Syndrome Coronavirus 2 Infection

중증 급성 호흡기 증후군 코로나 바이러스 2 감염 후 몇 개월 동안 항체 역가 중화의 역학

Major Articles and Brief Reports

Published on 2021-01-152022-09-12
Journal: The Journal of Infectious Diseases [Category] MERS, 진단,

[키워드] accompanied acute respiratory syndrome acute respiratory syndrome coronavirus antibody Antibody dynamics antibody levels Antibody titer Antibody titers Asymptomatic average B cell B cells binding collected coronavirus coronavirus 2 COVID-19 declined determine develop disease domain Dynamics expected fold followed by Frame immune response immune responses Immunity individual Infection initial longitudinal samples Mild moderate-severe Month MOST Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers Other respiratory viruses prospective cohort quantified RBD Receptor-binding domain respiratory respiratory viruses SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike Spike protein symptom onset time frames titer total antibodies total antibody Viral viral infection viral spike protein
[DOI] 10.1093/infdis/jiaa618 PMC 바로가기 [Article Type] Major Articles and Brief Reports

Emergency response for evaluating SARS-CoV-2 immune status, seroprevalence and convalescent plasma in Argentina

아르헨티나에서 SARS-CoV-2 면역 상태, 혈청 유병률 및 회복기 혈장 평가를 위한 긴급 대응

Research Article

Published on 2021-01-142022-08-13
Journal: PLoS Pathogens [Category] Biochemistry, 진단, 치료기술,

[키워드] acute and convalescent antibody responses antibody antibody kinetics antibody levels antibody quantification Antibody Response Antibody responses Antibody titers assays Asymptomatic Asymptomatic case Asymptomatic cases Author clinical trial clinical trials Combination compassionate use convalescent convalescent plasma country COVIDAR detect Donor donors ELISA ELISA test Emergency end point enzyme-linked immunosorbent enzyme-linked immunosorbent assay epidemiological evaluate Evolution framework generate Guidance health authorities Health care health care workers health institution hospital hospitalized patient hospitalized patients IgG and IgM IgG antibody IgG antibody titer IgG antibody titers IgM IgM and IgG immune response immune responses Immune status infected individual infected individuals information Kinetics Longitudinal studies longitudinal study management median neutralizing antibody titers nursing homes over pandemic Patient plasma positive correlation powerful tool produced profiles protocol protocols provided public health quantification RBD Receptor binding domain robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections Seroconversion seroconversion time serologic assay serologic test serologic testing Spike protein standardized protocol standardized protocols symptomatic and asymptomatic Symptomatic patients symptoms onset Therapies therapy trimer was used
[DOI] 10.1371/journal.ppat.1009161 PMC 바로가기 [Article Type] Research Article