Robust and Persistent B- and T-Cell Responses after COVID-19 in Immunocompetent and Solid Organ Transplant Recipient Patients면역 적합성 및 고체 장기 이식 수용자 환자에서 COVID-19 후 강력하고 지속적인 B- 및 T- 세포 반응Article Published on 2021-11-112022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] analysed anti-Nucleocapsid IgG anti-Spike IgG antibody Antibody Response Antibody responses assays CD4 CD8 comparable COVID-19 Cytokines declined determined by develop elicited ELISA envelope envelope protein IgA IgG immune response immunocompetent patients Immunocompromised Immunocompromised patient Immunocompromised patients induced Infection lymphoproliferative membrane membrane protein mild symptoms Neutralization assay Neutralizing antibodies neutralizing antibody nucleocapsid protein Nucleocapsid proteins organ Patient patients patients with pneumonia peptide peptide pool peptide pools persistence persistent Pneumonia proliferative Protein recipient response SARS-CoV-2 SARS-COV-2 infection Solid solid organ spike Spike protein Stimulation T-cell Response T-cell responses the Spike Transplant transplanted patients was determined [DOI] 10.3390/v13112261 PMC 바로가기 [Article Type] Article
Humoral response to SARS‐CoV‐2 and seasonal coronaviruses in COVID‐19 patientsCOVID-19 환자의 SARS-CoV-2 및 계절성 코로나바이러스에 대한 체액 반응Research Article Published on 2021-11-082022-09-10 Journal: Journal of medical virology [Category] MERS, SARS, 치료법, [키워드] 229E acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody antibody levels Antibody Response Antibody responses association both groups Cohort control group convalescent plasma coronavirus Coronaviruses correlated correlation COVID COVID‐19 patient Definition disease severity Donor elevated Evidence evidence of HCoV HCoV 229E high responder human coronavirus human coronaviruses humoral humoral immune response Humoral response immunoassay in both group individual Infection lead levels of antibodies levels of antibody no evidence of nucleocapsid Postinfection predisposition Prevalence Protein respiratory SARS‐CoV‐2 SARS‐CoV‐2 antibodies SARS‐CoV‐2 antibody SARS‐CoV‐2 seasonal coronavirus seasonal coronaviruses severe acute respiratory syndrome Coronavirus significantly symptom onset tested while [DOI] 10.1002/jmv.27427 PMC 바로가기 [Article Type] Research Article
Longitudinal clinico-serological analysis of anti-nucleocapsid and anti-receptor binding domain of spike protein antibodies against SARS-CoV-2SARS-CoV-2에 대한 스파이크 단백질 항체의 항-뉴클레오캡시드 및 항-수용체 결합 도메인의 종단 임상-혈청 분석Article Published on 2021-11-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료법, [키워드] 240 days Analysis antibody Antibody Response Antibody responses Antibody titer Antibody titers Antigen Asymptomatic binding domain Clinical data collected correlated correlation COVID-19 patient COVID-19 patients Critical disease Disease progression Disease spectrum evaluated First wave followed by IgG IgG antibody IgG antibody response IgG response increase in longitudinal monitoring N protein NAb nAb response NAb titer NAb titers NAbs neutralizing antibody Neutralizing antibody response nucleocapsid pandemic Patient persistence POD post infection progression Protein RBD Re-infection Receptor binding domain response robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic severe disease Spike protein symptomatic symptomatic status the antibody response the disease the SARS-CoV-2 [DOI] 10.1016/j.ijid.2021.09.024 PMC 바로가기 [Article Type] Article
Anti-spike antibody response to natural SARS-CoV-2 infection in the general population일반 인구에서 자연적인 SARS-CoV-2 감염에 대한 항스파이크 항체 반응Article Published on 2021-10-292022-09-12 Journal: Nature Communications [Category] MERS, SARS, 진단, [키워드] anti-spike antibodies anti-Spike IgG antibody antibody levels Antibody Response Antibody responses average Bayesian booster Community COVID-19 infection Cycle threshold value determinant determinants Epidemiology estimate feature female General population immune response infected with SARS-CoV-2 Infection latent class less linear MOST Older participant PCR tests peak level Planning positive swab Reinfection reported responders risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR test seroconvert seroconverted Severe infection subsequent Symptoms the antibody response trajectory understanding United Kingdom vaccination viral burden viral infection [DOI] 10.1038/s41467-021-26479-2 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Antibody Binding and Neutralization in Dried Blood Spot Eluates and Paired Plasma건혈 반점 용출액 및 짝을 이루는 혈장에서 SARS-CoV-2 항체 결합 및 중화Research Article Published on 2021-10-202022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 변종, 진단, [키워드] 384-well format acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adoption ambient ambient temperature antibodies antibody Antibody binding Antibody Response Antibody responses binding Blood cold chain cold temperatures collected convalescent coronavirus correlated COVID-19 COVID-19 pandemic Critical dried blood spot Dried blood spots ELISA Eluate enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay epitope epitope mapping equipment evaluate feature fingerstick immune response immune responses Infection invasive Longevity MOST natural infection neutralization assays Neutralizing antibodies neutralizing antibody overcome phage display plasma plasma antibody Population profile reflected respiratory responses risk SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody response SARS-CoV-2 antibody responses SARS-CoV-2 neutralization SARS-CoV-2 variant sera severe acute respiratory syndrome Coronavirus specific antibodies spot storage Support temperature vaccinated individuals vaccination variety venipuncture venous venous blood while [DOI] 10.1128/Spectrum.01298-21 PMC 바로가기 [Article Type] Research Article
COVID-19 serological evaluation in a cohort of Vaccinated and Seropositive healthcare workers백신 접종 및 혈청 양성 반응을 보이는 의료 종사자 집단에서 COVID-19 혈청학적 평가Article Published on 2021-10-192022-09-11 Journal: Acta bio-medica : Atenei Parmensis [Category] MERS, SARS, 진단, 치료법, [키워드] Acquired age Anti-nucleocapsid antibodies anti-nucleocapsid antibody antibody antibody levels Antibody Response Antibody responses Antibody titer Antibody titers association booster carried category cellular childbearing age chronic degenerative diseases Cohort Complete Course COVID-19 cut-off value degenerative disease dose evaluate examined females Gender greater health problem healthcare worker Healthcare workers Humoral immunity IgG immune system immunoassay Infection material molecular nucleocapsid Pfizer positive positive swab present promote public health R software reported respiratory SARS-CoV-2 serological serological assessment Sex single dose spike statistically significant stratified subject suggested Swab vaccination Vaccine vaccine dose women [DOI] 10.23750/abm.v92iS6.12261 PMC 바로가기 [Article Type] Article
APC-Targeted DNA Vaccination Against Reticulocyte-Binding Protein Homolog 5 Induces Plasmodium falciparum -Specific Neutralizing Antibodies and T Cell ResponsesAPC-표적 DNA 백신이 망상적혈구 결합 단백질 호모로그 5에 대해 플라스모디움 팔시파룸 특이적 중화 항체 및 T 세포 반응을 유도한다.Original Research Published on 2021-10-182024-08-08 Journal: Frontiers in immunology [Category] 말라리아, [키워드] Antibody responses APC-targeting DNA vaccines GIA malaria PfRH5 T cell responses [DOI] 10.3389/fimmu.2021.720550 PMC 바로가기 [Article Type] Original Research
Low-dose mRNA-1273 COVID-19 vaccine generates durable memory enhanced by cross-reactive T cells저용량 mRNA-1273 Covid-19 백신은 교차 반응성 T 세포에 의해 강화 된 내구성 기억을 생성합니다.Article Published on 2021-10-082022-09-10 Journal: Science (New York, N.y.) [Category] Fulltext, MERS, 임상, 진단, [키워드] age Antibody Response Antibody responses binding antibody boost CD4 CD8 Cell cells comparable COVID-19 cases cross-reactive examined follicular generate groups helper cells Immunity immunization Impact memory Moderna mRNA-1273 vaccine mRNA-1273 COVID-19 vaccine Neutralizing antibody response neutralizing antibody responses subject subjects T cell T cell memory T cells T follicular helper cells the vaccine [DOI] 10.1126/science.abj9853 PMC 바로가기 [Article Type] Article
Immunoglobulin G antibody response to the Sputnik V vaccine: previous SARS-CoV-2 seropositive individuals may need just one vaccine dose스푸트니크 V 백신에 대한 면역글로불린 G 항체 반응: 이전에 SARS-CoV-2 혈청 양성 반응을 보인 개인은 단 한 번의 백신 접종이 필요할 수 있습니다.Article Published on 2021-10-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료법, [키워드] antibody antibody levels Antibody Response antibody response against Antibody responses booster dose Cohort develop domain dose doses enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated had no IgG IgG antibodies IgG antibody IgG immune response IgG response Immunoglobulin Immunoglobulin G individual individuals nucleocapsid protein nucleocapsid protein (NP) RBD receiving Receptor-binding domain Receptor-binding domain (RBD) S/P S/P ratio SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens second dose seronegative seropositive seropositive individual seropositive subject seropositive subjects significant increase Spike protein Sputnik V vaccine the receptor-binding domain the spike protein the vaccine triggered vaccination Vaccine vaccine booster dose. vaccine dose Venezuela [DOI] 10.1016/j.ijid.2021.07.070 PMC 바로가기 [Article Type] Article
Multicenter evaluation of four immunoassays for the performance of early diagnosis of COVID-19 and assessment of antibody responses of patients with pneumonia in TaiwanObservational Study Published on 2021-10-012023-06-19 Journal: Journal of microbiology, immunology, and infection [Category] MERS, SARS, [키워드] Antibody responses COVID-19 False positive immunoassays Pneumonia [DOI] 10.1016/j.jmii.2021.02.003 PMC 바로가기 [Article Type] Observational Study