Biological – Page 14 – Communicable Diseases Research

Toward Consensus on Correct Interpretation of Protein Binding in Plasma and Other Biological Matrices for COVID‐19 Therapeutic Development

COVID-19 치료제 개발을 위한 혈장 및 기타 생물학적 매트릭스의 단백질 결합에 대한 올바른 해석에 대한 합의를 향하여

Review

Published on 2020-11-212022-09-10
Journal: Clinical Pharmacology and Therapeutics [Category] SARS, 신약개발, 치료제,

The Lebanese COVID-19 Cohort; A Challenge for the ABO Blood Group System

Medicine

Published on 2020-11-202022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

Study of Clinical and Biological Characteristics of Moroccan Covid-19 Patients With and Without Olfactory and/or Gustatory Dysfunction

Physiology

Published on 2020-11-192022-10-31
Journal: Frontiers in Physiology [Category] COVID-19,

[키워드] 1:1 acute respiratory syndrome age Ageusia Anosmia average Biological biological parameters body mass index carried Characteristics clinical Clinical characteristics clinical outcomes Clinical symptoms Comorbidity coronavirus disease Coronavirus-2 cough COVID-19 cross-sectional D-dimer database death demographic characteristics diagnosis of COVID-19 effort elevated Epidemic epidemiological epidemiological situation Fever Health Hemostasis IMPROVE include infected patient lactate dehydrogenase Liver function Lymphocytes lymphopenia majority marker morbidity and mortality Moroccan patients Morocco myalgia pandemic parameter parameters Patient patients performed Platelet previous study Protein provide reactive reported Result SARS-CoV-2 Sex significant difference Spread Symptom Symptomatic patients the disease the patient the SARS-CoV-2 the WHO viral infection
[DOI] 10.3389/fphys.2020.595005 PMC 바로가기 [Article Type] Physiology

Biological Context Linking Hypertension and Higher Risk for COVID-19 Severity

Physiology

Published on 2020-11-192022-10-31
Journal: Frontiers in Physiology [Category] COVID-19,

[키워드] ACE2 acute respiratory distress acute respiratory syndrome addition Admission age aggravate angiotensin-converting enzyme 2 Arterial hypertension Arterial stiffness Biological biological plausibility caused changes in Comorbidity Context contribute coronavirus coronavirus disease COVID COVID-19 COVID-19 patients COVID-19 severity death Dipeptidyl peptidase 4 disease Disease progression DPP4 dysregulated Endothelial dysfunction enzyme Gender hemodynamic hemodynamic factors higher risk hypertension immune system increased risk Inflammation inhibitors intensive care male manifestation mechanism Mortality multifunctional myocardial injury observation pathophysiology patients with COVID-19 presence of comorbidity proportions public health crisis renin-angiotensin system risk factor SARS-CoV-2 SARS-COV-2 infection shown syndrome target cells the SARS-CoV-2 this system Transmissibility
[DOI] 10.3389/fphys.2020.599729 PMC 바로가기 [Article Type] Physiology

Low-impact social distancing interventions to mitigate local epidemics of SARS-CoV-2

Article

Published on 2020-11-012023-07-11
Journal: Microbes and infection [Category] SARS,

[키워드] Biological COVID-19 Herd Immunity models SARS-CoV-2
[DOI] 10.1016/j.micinf.2020.09.006 PMC 바로가기

The Structure of the Membrane Protein of SARS-CoV-2 Resembles the Sugar Transporter SemiSWEET

Research Article

Published on 2020-10-192022-10-28
Journal: Pathogens and Immunity [Category] COVID-19,

[키워드] acute respiratory syndrome Amino acid Analysis autophagy Biological cause coronavirus COVID-19 Critical diabete domain endocytosis envelope protein experiment form function glycoprotein glycosylated glycosylation Health help homologous homology immune evasion in silico include induce influence interact involved lysosomal M protein maintain maturation membrane membrane glycoprotein membranes MERS-CoV N protein nucleocapsid protein pandemic pathway proliferation Protein receptor Replication responsible risk RNA viruses S protein SARS-CoV SARS-CoV-2 SemiSWEET similarity structural protein Structure sucrose sugar Sugar transporter the disease the S protein the SARS-CoV-2 virus the spike protein Transport transporter Vesicle virus wild animals
[DOI] 10.20411/pai.v5i1.377 PMC 바로가기 [Article Type] Research Article

“Acute Myocardial Infarction in the Time of COVID-19”: A Review of Biological, Environmental, and Psychosocial Contributors

Review

Published on 2020-10-092022-10-29
Journal: International Journal of Environmental Research an [Category] COVID-19, MERS,

[키워드] Acute myocardial infarction Admission Biological biological pathway cardiac event cardiovascular comorbidities cardiovascular risk factors characterized complex complications Coronavirus disease 2019 Covid patients COVID-19 decrease Endothelial dysfunction Evidence explain Factor fear Health immune In-hospital incidence Increased induce Infection Inflammation Inflammatory responses morbidity and mortality Mortality myocardial damage myocardial injury Patient plaque instability Pollution procoagulant Psychological distress Psychosocial reduction in Respiratory disease response review risk factor severity subsequent Symptoms symptoms onset time
[DOI] 10.3390/ijerph17207371 PMC 바로가기 [Article Type] Review

Preemptive interleukin-6 blockade in patients with COVID-19

Article

Published on 2020-10-082022-10-04
Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 치료제,

[키워드] antibody anticipated Biological blockade C-reactive protein catastrophic clinical manifestation clinical marker collected Comorbidity consequence contributing to COVID-19 criteria Cytokine release syndrome Cytokine storm D-dimer death disease evaluated Final Gender Health care humanized implicated In-hospital inclusion criteria Infectious diseases initial interleukin-6 key factor monoclonal Nasopharyngeal swab nasopharynx non-responder outcome outcomes Patient patients patients hospitalized patients with COVID-19 plasma biomarker predicted predictor predictors Prevent profile receptor Responder Safe severely ill patients Signaling SOFA SOFA score Stage Systolic blood pressure Temporal the SARS-CoV-2 therapy Tocilizumab treated with COVID-19
[DOI] 10.1038/s41598-020-74001-3 PMC 바로가기 [Article Type] Article

Qualitative and Quantitative Analysis of Ukrainian Iris Species: A Fresh Look on Their Antioxidant Content and Biological Activities

Article

Published on 2020-10-082022-10-30
Journal: Molecules [Category] Coronavirus, MERS,

Histopathological findings and viral tropism in UK patients with severe fatal COVID-19: a post-mortem study

심각한 치명적인 COVID-19를 가진 영국 환자의 조직병리학적 발견 및 바이러스 친화성: 사후 연구

Article

Published on 2020-10-012022-09-11
Journal: The Lancet. Microbe [Category] SARS, 치료기술,

[키워드] Activation active viral replication acute pancreatitis acute respiratory syndrome alveolar damage aortic dissection Autopsies Autopsy Biological Biotechnology Brain Case series cause of death Clinical course Clinical data clinically Cohort Comprehensive coronavirus Council COVID-19 death description Diagnosis died diffuse Diffuse alveolar damage disseminated mucormycosis dominant eight eligible Endocarditis Evidence evidence of examined feature FIVE Genome heart high mortality rate histopathological finding histopathological findings Immune cell Immunohistochemical analysis Infarction Infection Injury IQR kidney lung lymphocyte Major major organs marantic endocarditis median age microglial Mucormycosis nine Older organ Pancreatitis Pathologists Patient patients Pericarditis Post-mortem provided Quantitative reported respiratory respiratory tract RT-PCR analysis sampling Science severe acute respiratory syndrome Coronavirus severe COVID-19 subset Support T cells thrombosis thrombotic tissue sample tissue samples transcript Viral viral genomes Viral RNA viral tropism was done Wellcome Trust
[DOI] 10.1016/S2666-5247(20)30115-4 PMC 바로가기 [Article Type] Article