Omicron BA.2 (B.1.1.529.2): high potential to becoming the next dominating variantArticle Published on 2022-02-102022-10-28 Journal: ArXiv [Category] COVID-19, [키워드] acute respiratory syndrome algebraic Analysis antibody resistance antibody-resistance Beta contagious coronavirus COVID-19 deep learning Delta delta variant evaluate favor Gamma GlaxoSmithKline higher infectivity Infectivity Lambda Lineage mAbs Mutation natural selection omicron Patient question replaced reported SARS-CoV-2 SARS-CoV-2 variant Vaccine Vaccine breakthrough Vaccines variant PMC 바로가기 [Article Type] Article
Activation of Immune System May Cause Pathophysiological Changes in the Myocardium of SARS-CoV-2 Infected Monkey Model면역 체계의 활성화는 SARS-CoV-2에 감염된 원숭이 모델의 심근에 병태생리학적 변화를 일으킬 수 있음Article Published on 2022-02-102022-09-11 Journal: Cells [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] ACE2 receptor acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus analyzed cardiovascular cause change characterized collagen collected contagious contagious disease contribute coronavirus COVID-19 COVID-19 patients damages disease disorder eosin fibrosis foci heart heart failure heart tissue hearts hematoxylin Hematoxylin and eosin hypertrophy immunohistochemical staining induce Infection inflammatory cell inflammatory cells inflammatory immune response interstitial lead Lymphocytes Macrophage macrophages majority Model Monkey Myocardial myocarditis Myocardium pathological change pathological changes perivascular positive progression Region respiratory respiratory tract SARS-CoV-2 SARS-CoV-2 antigen SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe complications staining subsequent System T lymphocyte T lymphocytes the disease tissue tissue sample ventricular virus virus particle virus particles [DOI] 10.3390/cells11040611 PMC 바로가기 [Article Type] Article
Mitigation strategies to safely conduct HIV treatment research in the context of COVID‐19COVID-19의 맥락에서 HIV 치료 연구를 안전하게 수행하기 위한 완화 전략Commentary Published on 2022-02-092022-09-10 Journal: Journal of the International AIDS Society [Category] COVID19(2023년), MERS, SARS, 변종, [키워드] acquisition AIDS ambition analytical treatment interruption (ATI) Antiretroviral therapy ART assumed benefit best Clinical research clinical trial clinical trials Community contagious COVID‐19 COVID‐19 Critical develop effective Effectiveness evaluated expected Factor feasibility Guidance guideline high risk HIV HIV disease HIV treatment key consideration key considerations Local management Mitigation pandemic pathogenic PLWH populations progression reduced Research risk risk mitigation Safe SARS‐CoV‐2 SARS‐CoV‐2 Society Treatment strategies treatment strategy Uncertainty variants with HIV [DOI] 10.1002/jia2.25882 PMC 바로가기 [Article Type] Commentary
Insight into the Advances in Clinical Trials of SARS-CoV-2 VaccinesReview Article Published on 2022-02-092022-10-31 Journal: The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien des Maladies Infectieuses et de la Microbiologie Médicale [Category] COVID-19, [키워드] acute respiratory syndrome administration advance approved ChAdOx1 clinical clinical trial complications contagious CoronaVac Coronavirus-2 COVID-19 vaccine effective Efficacy Emergency use authorization evaluate Gam-COVID-Vac healthcare Immunity Infection insight Intervention janssen limit mixture Moderna mRNA mutant strain neutralizing antibody Occurrence pandemic peptide Prevent proportion reported robust SARS-CoV-2 Scientific community shown Spread tested the SARS-CoV-2 Vaccinating vaccination Vaccine Vaccines variants virus [DOI] 10.1155/2022/6913772 PMC 바로가기 [Article Type] Review Article
Risk Factors for Severe COVID-19 in Children: A Systematic Review and Meta-Analysis소아에서 심각한 COVID-19의 위험 요소: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-02-072022-09-11 Journal: Journal of Korean medical science [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval achievement acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission Adults age article Asthma children children with COVID-19 chronic lung disease chronic lung diseases Clinical course Comorbidities Comorbidity contagious coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 criteria Critical illness database death Decision making diabete diabetes disease disorder disorders Enrollment Factor heart disease help high risk Hospital admission Hospitalization hospitalizations Immunocompromised immunocompromised status Infant infected with SARS-CoV-2 intensive care intensive care unit admission Invasive mechanical ventilation Lung disease Meta-analysis Neonate neurologic obesity outcome Premature Prematurity Prevalence priority review risk risk factor Risk factors risk ratio risk stratification SARS-CoV-2 SARS-COV-2 infection screened Seizure severe COVID-19 subgroup analysis systematic review vaccination vaccination rate variant variants was performed [DOI] 10.3346/jkms.2022.37.e35 PMC 바로가기 [Article Type] Meta-Analysis
Chest X-ray Classification for the Detection of COVID-19 Using Deep Learning Techniques딥 러닝 기술을 사용한 COVID-19 검출을 위한 흉부 X선 분류Article Published on 2022-02-052022-09-10 Journal: Sensors (Basel, Switzerland) [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] Accuracy chest X-ray chest X-rays classification contagious coronavirus COVID-19 COVID-19 infection dataset deep deep learning detection Diagnosis diagnosis of COVID-19 Diseases domain health system IMPROVE include infections learning life lung Non-COVID-19 outperform pandemic parameter path PCR testing Pneumonia Precision pressure recent Safe significantly technique transfer learning Viral Viral pneumonia X-ray [DOI] 10.3390/s22031211 PMC 바로가기 [Article Type] Article
Molecular dynamic simulation analysis of SARS-CoV-2 spike mutations and evaluation of ACE2 from pets and wild animals for infection riskSARS-CoV-2 스파이크 돌연변이의 분자 역학 시뮬레이션 분석 및 감염 위험에 대한 애완 동물 및 야생 동물의 ACE2 평가Article Published on 2022-02-012022-09-11 Journal: Computational biology and chemistry [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 ACE2 receptor ACE2 receptor recognition Analysis animal Animal host binding binding ability binding affinity caused contagious coronavirus disease Coronavirus disease 2019 Course COVID-19 Critical glycoprotein health emergency Host human ACE2 humans infection risk interact Interaction intermediate host life Missense mutation Missense mutations modeling mole molecular dynamics molecular dynamics simulations Molecular modeling Mus mutant Mutation mutations PALM Pandemics pangolin question RBD RBD region Receptor-binding domain reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 sequence SARS-CoV-2 sequences SARS-CoV-2 spike SARS-CoV-2 spike protein SARS-CoV-2 transmission spike gene spike glycoprotein Spike mutant Spike protein Stress susceptibility the binding affinity the RBD the receptor-binding domain the SARS-CoV-2 the spike protein transmission of SARS-CoV-2 transmitted viral spike virus vole wild animal wild animals [DOI] 10.1016/j.compbiolchem.2021.107613 PMC 바로가기 [Article Type] Article
A dynamic simulation study of FDA drug from zinc database against COVID-19 main protease receptorCOVID-19 주요 프로테아제 수용체에 대한 아연 데이터베이스에서 FDA 약물의 동적 시뮬레이션 연구Article Published on 2022-02-012022-08-31 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), MERS, SARS, 치료제, [키워드] accelerate approved binding calculated clinical study Compound compounds contagious COVID-19 database death drug drug candidate enzyme FDA FDA drugs FDA-approved drug FDA-approved drugs global public health globe Glu166 identify in silico Approach in vitro in vivo Initially lead library main protease MD simulation molecular molecular docking molecular dynamic simulation molecular dynamics MPro outbreak PCA protease provide receptor Research residue responsible RMSD RMSF SARS-CoV-2 selected Seven Spread trajectory was used Zinc ZINC database zinc database. [DOI] 10.1080/07391102.2020.1821785 PMC 바로가기 [Article Type] Article
Predicted HLA Class I and Class II Epitopes From Licensed Vaccines Are Largely Conserved in New SARS-CoV-2 Omicron Variant of Concern허가된 백신에서 예측된 HLA 클래스 I 및 클래스 II 에피토프는 우려의 새로운 SARS-CoV-2 오미크론 변이체에서 크게 보존됩니다Immunology Published on 2022-01-282022-09-11 Journal: Frontiers in Immunology [Category] 변종, [키워드] alleles analyzed cellular Cellular immune response class concern contagious Critical cytotoxic Efficacy elicited epitope Epitopes escape mutant escape mutation facilitate HLA HLA class 1 HLA class 2 HLA class I HLA class I and II alleles human population immune protection immune responses issue Mutation New new SARS-CoV-2 omicron SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants These data Vaccine vaccine efficacy variant virus [DOI] 10.3389/fimmu.2022.832889 PMC 바로가기 [Article Type] Immunology
Presence and stability of SARS-CoV-2 on environmental currency and money cards in Utah reveals a lack of live virus유타의 환경 통화 및 머니 카드에 대한 SARS-COV-2의 존재 및 안정성은 살아있는 바이러스가 부족하다는 것을 보여줍니다Research Article Published on 2022-01-252022-09-10 Journal: PLoS ONE [Category] SARS, 치료기술, [키워드] 24 hours 48 hours Brigham Young Campus coins Community contagious COVID-19 pandemic credit cards favor greater initial investigated lack Live virus microbial pathogen Pathogens plastic Presence reduction in reveal room temperature SARS-CoV-2 SARS-CoV-2 RNA shown Spread stability suggested supported swabbing temperature the United State Transmission United States university Utah Viral Viral detection virus [DOI] 10.1371/journal.pone.0263025 PMC 바로가기 [Article Type] Research Article