Novel coronavirus pathogen in humans and animals: an overview on its social impact, economic impact, and potential treatments인간과 동물의 신종 코로나바이러스 병원체: 사회적 영향, 경제적 영향 및 잠재적 치료법에 대한 개요Review Published on 2021-12-012022-09-11 Journal: Environmental science and pollution research inter [Category] SARS, 유전자 메커니즘, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 animals caused coronavirus coronavirus disease CoV COVID-19 COVID-19 mortality deaths Economy emerging pathogens exceeded Health Health Organization Human human pathogen humans Infection international public health lethal disease lockdowns measure mechanism MERS Middle East Middle East respiratory syndrome movement National novel Novel coronavirus outbreak pandemic pandemic of COVID-19 pathogen pathogenicity Pathogens Potential Potential treatment SARS-CoV SARS-CoV-2 SARS-CoV-2 virus Sequencing severe acute respiratory syndrome Coronavirus Social impact. spread to Symptoms syndrome therapy for COVID-19 Transmission Travel viral disease WHO World Health Organization worldwide pandemic [DOI] 10.1007/s11356-021-16809-8 PMC 바로가기 [Article Type] Review
Understanding the role of nACE2 in neurogenic hypertension among COVID-19 patients Reviews Published on 2021-11-302022-10-05 Journal: Hypertension research : official journal of the Ja [Category] COVID19(2023년), SARS, 진단, 치료제, [키워드] ACE2 adipose association binding blood pressure Brain cardiovascular disease Complication coronavirus disease COVID-19 COVID-19 mortality COVID-19 patient creating Cytokine storms decrease diabetes Effect enzyme expressed Gut host cell host cells hypertension Inflammatory responses Interaction kidneys Lungs Mortality neuronal new strain pandemic Patient presence of comorbidity provide RAS Region regulate Regulation responsible SARS-CoV-2 SARS-COV-2 infection severity of COVID-19 Spread tissue understanding vaccination Vaccines Variation virus [DOI] 10.1038/s41440-021-00800-4 [Article Type] Reviews
Optimising health and economic impacts of COVID-19 vaccine prioritisation strategies in the WHO European Region: a mathematical modelling studyResearch Paper Published on 2021-11-302022-10-30 Journal: The Lancet Regional Health - Europe [Category] COVID-19, [키워드] Adults age applied benefit Characteristics combinations Commonwealth Comorbidity compartmental model conditions Contact country Coverage COVID-19 COVID-19 mortality COVID-19 vaccine development disease Efficacy Epidemic Europe European European Commission evaluated examined finding Foreign foundation funding GDP greater group groups Health health economics highest Immunity Impact incrementally Infection less lowest Mathematical modelling Medical Research Council Melinda Gate Metrics Model morbidity Mortality multicountry analysis office Older Optimising outcome Policy evaluation profile reached Region reported Stage structures tested the WHO United Kingdom Vaccine vaccine policy Wellcome Trust WHO World Health Organization [DOI] 10.1016/j.lanepe.2021.100267 PMC 바로가기 [Article Type] Research Paper
Determinants of the Underlying Causes of Mortality during the First Wave of COVID-19 Pandemic in Saudi Arabia: A Descriptive National StudyArticle Published on 2021-11-302022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] age Analysis analyzed approval cardiovascular cause classification collected data COVID-19 COVID-19 mortality COVID-19 pandemic CVD death deaths demographic characteristics determinant determinants died disease Health ICD-10 implication international classification of diseases Kingdom Kingdom of Saudi Arabia lockdown males mortalities Mortality Mortality statistics Non-communicable disease recommendations reduction in Registered retrospective road Saudi Arabia Sex underlying mortality Wave were used WHO [DOI] 10.3390/ijerph182312647 PMC 바로가기 [Article Type] Article
Predicting COVID-19 mortality risk in Toronto, Canada: a comparison of tree-based and regression-based machine learning methodsResearch Published on 2021-11-272022-10-28 Journal: BMC Medical Research Methodology [Category] COVID-19, Fulltext, MERS, SARS, [키워드] Accuracy AUC calibration slope Canada Care characteristic Classification trees comparable COVID-19 COVID-19 mortality disease extreme Extreme gradient boosting Generalized additive model Health healthcare infected individual Linear Discriminant Analysis Logistic Logistic regression mortality risk offer positive predict Predictive Predictive model random repeated reported Result risk study population Toronto [DOI] 10.1186/s12874-021-01441-4 PMC 바로가기 [Article Type] Research
Social deprivation as a risk factor for COVID-19 mortality among women and men in the UK Biobank: nature of risk and context suggests that social interventions are essential to mitigate the effects of future pandemicsOriginal Research Published on 2021-11-272022-10-29 Journal: Journal of epidemiology and community health [Category] Coronavirus, MERS, SARS, [키워드] 95% CI Adjustment age alleviate association associations baseline cardiovascular disease cause continuous scale COVD-19 COVID-19 COVID-19 mortality death Deprivation died Effect Effects Evidence Factor fatal influenza greater incidence Infection Intervention lack magnitude men mitigate Mortality National objective other diseases outcome measure Pandemics participant person years Pneumonia Prospective quantified Result resulting risk risk factor score setting Sex difference social class social deprivation UK biobank women [DOI] 10.1136/jech-2020-215810 PMC 바로가기 [Article Type] Original Research
Anti-SARS-CoV-2 IgG responses are powerful predicting signatures for the outcome of COVID-19 patientsAnti-SARS-CoV-2 IgG 반응은 COVID-19 환자의 결과에 대한 강력한 예측 신호입니다Article Published on 2021-11-262022-09-12 Journal: Journal of advanced research [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, [키워드] accessory protein Admission antibody association assumed Biomarker clinical information Clinical management Clinical outcome Comorbidities correlated COVID-19 COVID-19 mortality COVID-19 patient COVID-19 patients Cox proportional hazard demographics Disease progression disease severity Evidence global pandemic hospitalized COVID-19 patient identify IgG IgG antibody IgG response IgG responses implication Laboratory laboratory biomarker magnitude Microarray non-structural protein Non-structural/accessory protein nsp1 nsp10 Nsp7 NSP8 ORF3b Orf9b outcome outcomes Patient patient death patients positive rate Predicting signature predictive power Protein RdRP SARS-CoV-2 SARS-CoV-2 proteome SARS-CoV-2 specific antibody serum severity Severity of disease survivor symptoms onset was used [DOI] 10.1016/j.jare.2021.11.014 PMC 바로가기 [Article Type] Article
Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortalityResearch Article Published on 2021-11-262022-10-28 Journal: Science Advances [Category] COVID-19, [키워드] Accuracy acute respiratory syndrome adjusted hazard ratio age and sex antibody-dependent cellular cytotoxicity assessment benefit Cohort cohorts collected coronavirus COVID-19 COVID-19 mortality cytokine death description disease elevated feature help heterogeneity identify Immunoglobulin independent individuals log-transformed management marker Mortality on mechanical ventilation outcome Patient performed plasma Predictive predictor quantitation Receptor binding remained robust SARS-CoV-2 SARS-CoV-2 RNA symptom onset Therapies tissue injury Viral RNA vRNA [DOI] 10.1126/sciadv.abj5629 PMC 바로가기 [Article Type] Research Article
Prior fluid and electrolyte imbalance is associated with COVID-19 mortality Research Published on 2021-11-252022-10-05 Journal: Communications Medicine [Category] 바이오마커, [키워드] age Analysis Cancer Comorbidities Comorbidity COVID-19 COVID-19 mortality COVID-19 pandemic COVID-19 patient death Dementia diabetes diagnose early stage electrolyte imbalance Electronic health record identify immunological impairment increased risk individual Infection management Mortality multivariable pandemic Patient performed Prognostic factor public health threat renal renal function Result Retrospective analysis risk of death the disease univariable with COVID-19 [DOI] 10.1038/s43856-021-00051-x [Article Type] Research
Neutrophil-mediated oxidative stress and albumin structural damage predict COVID-19-associated mortality호중구 매개 산화 스트레스와 알부민 구조적 손상은 COVID-19 관련 사망률을 예측합니다Research Article Published on 2021-11-252022-09-12 Journal: eLife [Category] MERS, 진단, [키워드] accumulated albumin analyzed Anti-inflammatory anticoagulation antioxidant Blood blood sample candidate COVID-19 mortality COVID-19 treatment critically ill COVID-19 patients critically ill patients died Evidence faster Fatty acid functions healthy individual Human human serum albumin damage hydrogen peroxide in-hospital mortality indicated Kaplan–Meier survival analysis marker means median Mortality neutrophil Neutrophils non-survivor Non-survivors outcome oxidative stress parameter Patient plasma predict predicted Protein recruited reduced risk serum albumin severe patients significantly subject survivor the mean Transport Whole blood [DOI] 10.7554/eLife.69417 PMC 바로가기 [Article Type] Research Article