Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease
건강 및 면역 매개 질환의 여러 세포 유형에서 eQTL 매핑을 통한 유전자형-표현형 연관성에 대한 통찰력
Research Article
[키워드] Active disease
Affect
Analysis
anti-neutrophil cytoplasmic antibody
association
Autoimmune
Autoimmune diseases
blood cell
blood vessel
blood vessels
bowel
Cancer
cell types
cellular
cellular activation
clinical disease
complex
complex system
contribute
cytoplasmic
damage
database
dependent on
disease risk
disease-associated loci
DNA
Effect
eQTL
eQTL analysis
eQTL mapping
eQTLs
estimate
examined
Examining
expression
expression data
expression quantitative trait loci
FIVE
Gene Expression
Genetic
genetic control
Genetic studies
Genetic variant
genetic variants
genetics
Genome-wide association studies
Gut
GWAS
healthy
healthy control
healthy controls
help
Human immune system
human inflammatory diseases
identifying
immune
Immune cell
immune cell type
immune cells
immune-mediated diseases
in vitro
include
Infection
Inflammation
Inflammatory
Inflammatory bowel disease
inflammatory disease
Inflammatory diseases
insight
investigated
joint
knowledge
leucocyte
loci
majority
mapping
Multiple
observation
Pathogenesis
Patient
performed
proportion
PROTECT
provide
Quantitative
regions
resulting
risk
specificity
subset
subtype
tissue
tissues
Treatment
Type
variant
Vasculitis
White blood cell
[DOI] 10.1371/journal.pgen.1005908 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1005908 PMC 바로가기 [Article Type] Research Article