Genomic Diversity of SARS-CoV-2 Omicron Variant in South American Countries남미 국가에서 SARS-CoV-2 오미크론 변이체의 게놈 다양성Article Published on 2022-06-072022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단, [키워드] acquisition addition Analysis antibody B.1.1.529 Characteristics circulating variants continent contributed dispersal Diversity dominant epidemiological favor Genome genomic genomic information Genomic surveillance identify Lineage lineages mechanism Mutation mutations nucleotide nucleotide diversity omicron omicron sublineages Phylogenetic relationship Phylogenomic analysis provided public health SARS-CoV-2 South South America Surveillance Transmission variant [DOI] 10.3390/v14061234 PMC 바로가기 [Article Type] Article
Clinical Characteristics and Risk Factors for Mortality in Critical Coronavirus Disease 2019 Patients 50 Years of Age or Younger During the Delta Wave: Comparison With Patients > 50 Years in Korea2019년 델타파 중 50세 이하 환자 중대 코로나바이러스 감염증의 임상적 특성 및 사망률 위험인자: 국내 50세 이상 환자와의 비교Article Published on 2022-06-062022-09-11 Journal: Journal of Korean medical science [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval Adult patients age analyses Analysis analyzed Blood stream infection BMI body mass body mass index Case fatality rate clinical Clinical characteristics clinical feature Clinical features condition conditions coronavirus disease Coronavirus disease 2019 COVID-19 creatinine Critical critical condition death Delta delta variant diabetes Diabetes Mellitus died dominant eight electronic medical record enrolled evaluate Factor Fatality rate General population globe highest highlight hospital Hospitalized hypertension identify independent predictor independent predictors Infection measure mechanical ventilation Mortality mortality risk factor mortality risk factors Multivariate analysis nasal nasal cannula Numerous obese obesity Odds ratio Older older patient older patients oxygen Oxygen therapy Patient PCR-confirmed COVID-19 Prevent progression respiratory Respiratory Support risk risk factor Risk factors Secondary infection severity statistically study period study population the patient therapy total patients underlying disease vaccination vaccination rate Vaccinations variant while women Year Young younger patient younger patients [DOI] 10.3346/jkms.2022.37.e175 PMC 바로가기 [Article Type] Article
mRNA or ChAd0x1 COVID-19 Vaccination of Adolescents Induces Robust Antibody and Cellular Responses With Continued Recognition of Omicron Following mRNA-1273청소년의 mRNA 또는 ChAd0x1 COVID-19 예방 접종은 mRNA-1273에 이어 오미크론을 계속 인식하여 강력한 항체 및 세포 반응을 유도합니다Article Published on 2022-06-022022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Adolescent antibody antibody level antibody levels Antibody Response BNT162b2 CD4+ T-cell Cell cellular response Cellular responses ChAdOx1 comprehensive analysis COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines cytokine develop dominant Donor doses dual elicit Evidence generate health condition High-risk patients IL-10 immune response immune responses immunogenic Infection measure memory Mild mRNA mRNA vaccination mRNA vaccine mRNA-1273 natural infection neuro-disabilities neutralisation titre Neutralisation titres omicron Omicron variant paediatric physical populations reactivity Recognition remained response risk robust severe disease significantly increased single vaccination Strong T-cell T-cell Response T-cell responses T-cells These data vaccination Vaccine vaccine dose variant [DOI] 10.3389/fimmu.2022.882515 PMC 바로가기 [Article Type] Article
Emergency SARS-CoV-2 variants of concern: rapidly direct RT-qPCR detection without RNA extraction, clinical comparison, cost-effective, and high-throughput우려되는 긴급 SARS-CoV-2 변종: RNA 추출 없이 신속하게 직접 RT-qPCR 검출, 임상 비교, 비용 효율적 및 높은 처리량Article Published on 2022-06-022022-09-11 Journal: Aging (Albany NY) [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alternative method analytical sensitivity Chain Reaction characterized complex coronavirus coronavirus disease Coronavirus disease 2019 cost-effective diagnosis COVID-19 Diagnosis direct RT-qPCR dominant E gene Emergency Evolution faster gold gold standard High-throughput labor limit of detection mutations nasopharyngeal swabs Negative predictive value pandemic polymerase chain polymerase chain reaction positive Predictive value protocol real-time reverse transcriptase Real-time reverse transcriptase polymerase chain reaction reverse transcriptase Reverse transcriptase polymerase chain reaction RNA extraction RT-PCR RT-qPCR SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 VoC sensitivity severe acute respiratory syndrome Coronavirus significantly Spike protein thermocyclers variant variants variants of concern [DOI] 10.18632/aging.204095 PMC 바로가기 [Article Type] Article
Structural diversity of the SARS-CoV-2 Omicron spikeSARS-CoV-2 오미크론 스파이크의 구조적 다양성Article Published on 2022-06-022022-09-11 Journal: Molecular Cell [Category] COVID19(2023년), SARS, 변종, [키워드] affecting Analysis changes in communication conformational conformational change Critical cryo Cryo-electron microscopy cryo-EM structure cryo-EM structures Crystallography Delta delta variant determine domain dominant electron microscopy epitope fusion peptide immune immune evasion Impact interprotomer communication intraprotomer communication Mutation Neutralizing Neutralizing antibodies neutralizing antibody omicron Omicron spike peptide RBD Receptor-binding domain SARS-CoV-2 evolution spike Spike protein the SARS-CoV-2 Transmissibility variant vector analysis. virus transmissibility X-ray X-ray crystallography [DOI] 10.1016/j.molcel.2022.03.028 PMC 바로가기 [Article Type] Article
Augmented neutralization of SARS-CoV-2 Omicron variant by boost vaccination and monoclonal antibodies추가 백신 접종 및 단일 클론 항체에 의한 SARS-CoV-2 Omicron 변이체의 증강 중화Article Published on 2022-06-012022-09-11 Journal: European Journal of Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibodies antibody Antibody binding appearance approved binding BNT162b2 boost boost immunization candidate caused clinically coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Delta delta variant determine dominant Effective vaccines Efficacy Evidence flow cytometry immunization increase MONITOR monoclonal antibodies monoclonal antibody neutralization Neutralization assay neutralization assays neutralize neutralized Neutralizing neutralizing antibody omicron Omicron variant Omicron variants parental pathogenicity Protective pseudotyped SARS-CoV-2 recognize respiratory SARS-CoV-2 SARS-CoV-2 variants serum antibodies serum antibody serum titer serum titers severe acute respiratory syndrome Coronavirus Support therapeutic therapeutic antibodies titers Transmissibility vaccination Vaccine variant variants virus variant virus variants Wuhan strain [DOI] 10.1002/eji.202249841 PMC 바로가기 [Article Type] Article
Modelling the COVID-19 epidemic and the vaccination campaign in Italy by the SUIHTER modelResearch article Published on 2022-06-012022-10-05 Journal: Infectious Disease Modelling [Category] 변종, [키워드] analyses clinical evidence compartmental model COVID-19 COVID-19 epidemic COVID-19 pandemic death dominant Efficacy epidemiological Evolution extension feature Forecast Hospitalization Italy Prevent Scenario analyses Transmission transmission rate vaccination Vaccine variant virus variants [DOI] 10.1016/j.idm.2022.03.002 [Article Type] Research article
SARS-CoV-2 Immunohistochemistry In Placenta태반의 SARS-CoV-2 면역조직화학Article Published on 2022-06-012022-09-11 Journal: International journal of surgical pathology [Category] COVID19(2023년), SARS, 변종, 치료법, [키워드] COVID-19 delta variant diagnosing dominant electron microscopy immunohistochemistry Infection nucleocapsid nucleocapsid protein parental pathology Placenta placental Placental infection pregnant women Protein robust SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 virus Spike protein ultrastructure [DOI] 10.1177/10668969211067754 PMC 바로가기 [Article Type] Article
Posterior reversible encephalopathy syndrome – A pathology that should not be overlooked in the era of COVID-19후두 가역성 뇌병증 증후군 - 코로나19 시대에 간과해서는 안 될 병리학Case Reports Published on 2022-06-012022-09-11 Journal: The American journal of emergency medicine [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Antibiotics Aphasia Autoimmune diseases blindness Case report cause Computed tomography coronavirus coronavirus disease Coronavirus disease 2019 cortical cortical blindness Corticosteroid Corticosteroids cough COVID-19 delta variant Department described determine diagnosed with COVID-19 Diagnosis dominant drugs Dyspnea eclampsia Emergency emergency department Encephalopathy Europe exhibiting exposure to Fever full recovery general practitioner generalized tonic-clonic seizures had no hypertensive Immediate Infectious disease Infectious diseases Invasion knowledge lobes material medical history MRI nervous system neurological Neurological complication Neurological complications Neurological symptom Neurological symptoms occipital Organ failure outcome pathology Patient patients with COVID-19 Pneumonia Posterior Posterior reversible encephalopathy syndrome PRES presenting radiological receiving renal resolved SARS-CoV-2 SARS-CoV-2 pneumonia secondary to Seizures Sepsis severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe SARS Shortness of breath Symptom syndrome Thoracic Treatment variant [DOI] 10.1016/j.ajem.2022.03.005 PMC 바로가기 [Article Type] Case Reports
Development of a Test System to Detect the Omicron Variant of SARS-CoV-2 and the Frequency of Its Detection in PatientsSARS-CoV-2의 오미크론 변이체 및 환자의 검출 빈도를 감지하는 테스트 시스템 개발Article Published on 2022-06-012022-09-11 Journal: Bulletin of experimental biology and medicine [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] allele allele-specific reverse transcription PCR (AS-RT-PCR) B.1.1.529 clinical clinical samples collected contagiousness coronavirus detect detection development dominant exceptional first test Frequency Genome Genotype less Mutation mutations omicron Omicron variant Patient patients primer probe probes Region reverse transcription PCR RT-PCR SARS-CoV SARS-CoV 2 SARS-CoV-2 System Test [DOI] 10.1007/s10517-022-05524-0 PMC 바로가기 [Article Type] Article