SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN)영국에서 항체 음성 의료 종사자와 비교한 항체 양성 환자의 SARS-CoV-2 감염률: 대규모, 다기관, 전향적 코호트 연구(SIREN)Multicenter Study Published on 2021-04-172022-09-11 Journal: Lancet (London, England) [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI adjusted Analysis antibody Antibody test antibody test) Antibody testing assigned baseline clinically Cohort cohorts COVID-19 defined Department determined by effective eligible England enrolled enrolment Evidence first positive Follow-up frailty future infection had no hazard health-care hierarchy hospital Immunity incidence incidence density incidence rate include Increased individual individuals induce Infection infection rate infection rates infection with SARS-CoV-2 infections Linked data lower risk median median interval multicentre participant Participants PCR PCR positive PCR test PCR testing PCR tests PCR-confirmed Poisson distribution positive positive PCR positive PCR test Potential Primary infection Primary outcome prospective cohort study protective effect Public Health England questionnaire Questionnaires rate ratios recruited Region Reinfection risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR Scottish Seroconversion Support Symptom symptomatic and asymptomatic UK Government was done was used were excluded [DOI] 10.1016/S0140-6736(21)00675-9 PMC 바로가기 [Article Type] Multicenter Study
COVID-19 Diagnostic Strategies. Part I: Nucleic Acid-Based TechnologiesReview Published on 2021-04-172022-10-28 Journal: Bioengineering [Category] COVID-19, [키워드] activities Asymptomatic carriers caused Community coronavirus 2 COVID-19 COVID-19 diagnostics CRISPR/Cas system Critical death detect develop diagnostic test diagnostic tests facilitate hazard individual Infection Microarray microfluidic-based biosensors molecular MONITOR NA-based tests Outbreaks Pandemics Part pathogen patients point-of-care (PoC) detection polymerase chain reaction (PCR), sequencing positive patient pre-symptomatic provide respiratory respiratory infection resulting SARS-CoV-2 Spread stages Support technology the disease the SARS-CoV-2 viral spread [DOI] 10.3390/bioengineering8040049 PMC 바로가기 [Article Type] Review
A systematic review of health sector responses to the coincidence of disasters and COVID-19Research Published on 2021-04-132022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, [키워드] Abstract affected affecting Analysis approach article caused Chinese complex conducted COVID-19 COVID-19 pandemic database Descriptive analysis Disasters earthquake events explained Factor Final form Google Scholar hazard Health Health sector health system health systems Healthcare professional Healthcare system identify implication IMPROVE inclusion criteria increasingly initial search investigated library Occurrence pandemic Pandemics performed Pneumonia Region reported Research researcher researchers response Result risk searched systematic review was done was selected Web while with COVID-19 World Health Organization Wuhan [DOI] 10.1186/s12889-021-10806-9 PMC 바로가기 [Article Type] Research
Comparative assessment of mortality risk factors between admission and follow-up models among patients hospitalized with COVID-19Research article Published on 2021-04-012022-10-05 Journal: International Journal of Infectious Diseases [Category] SARS, 바이오마커, [키워드] 28-day mortality Admission Biomarkers bpm Brazil C-reactive protein calculated changed clinical factor Clinical sign collected Comparative Confirmed COVID-19 infection coronavirus COVID-19 Cox regression model Follow-up hazard hazard ratio help Hospitalization in-hospital mortality Inclusion lactate dehydrogenase mechanical ventilation Mortality mortality risk factor objective oxygen saturation oxygen support Patient patients patients hospitalized peripheral oxygen saturation prognosis of patient remained respiratory rate Result retrospective cohort study risk factor urea with COVID-19 [DOI] 10.1016/j.ijid.2021.03.013 [Article Type] Research article
The global viralization of policies to contain the spreading of the COVID-19 pandemic: Analyses of school closures and first reported casesResearch Article Published on 2021-04-012022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] acting Affect Analysis applied China country COVID-19 COVID-19 case Epidemics evaluate hazard Health health emergency health system health systems increase in information International Italy measure Outbreaks pandemic Ratio reported Result Schools Seven Standard deviation survival the epidemic the WHO variety while WHO World Health Organization [DOI] 10.1371/journal.pone.0248828 PMC 바로가기 [Article Type] Research Article
Characterizing COVID-19 clinical phenotypes and associated comorbidities and complication profilesCOVID-19 임상 표현형 및 관련 동반 질환 및 합병증 프로필 특성화Research Article Published on 2021-03-312022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, [키워드] Admission Analysis association Characteristics clinical outcomes clinical phenotype clinical phenotypes Clinical practice Clustering collected Comorbidities Comorbidity Complication complications coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients COVID-19 phenotypes database death determine facilitate Future hazard hematologic hematological highest hospitalized patient hospitalized patients hospitals I, II identification identify IMPROVE in-hospital complication increases in Multivariable models outcome outcomes Patient patient population phenotype Phenotypes Principal component principal component analysis profile Regression model renal Research respiratory Result Retrospective analysis therapy Trial utility variable was performed with COVID-19 [DOI] 10.1371/journal.pone.0248956 PMC 바로가기 [Article Type] Research Article
Ethnicity, household composition and COVID-19 mortality: a national linked data studyResearch Published on 2021-03-242022-10-30 Journal: Journal of the Royal Society of Medicine [Category] COVID-19, MERS, SARS, [키워드] 95% CI 95% confidence interval Causal census Characteristics children clinical Community confounding factors COVID-19 COVID-19 mortality death elderly elevated England ethnic studies Ethnicity explained Factors groups hazard hazard ratio Health Hospital Episode Statistics housing and health increased risk Infectious diseases Mediation analysis men men and women National objective Older outcome measure participant prevalent proportion public health Public health intervention Result retrospective data risk risk of COVID-19 setting South Asian white women younger people [DOI] 10.1177/0141076821999973 PMC 바로가기 [Article Type] Research
Modeling the Contribution of Male Testosterone Levels to the Duration of Positive COVID Testing among Hospitalized Male COVID-19 PatientsArticle Published on 2021-03-242022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Affect Bacterial Cell COVID COVID-19 COVID-19 patient COVID-19 testing Duration estimates evaluated Evidence explain greater hazard help Hospital admission hospitalized COVID-19 patients immune response Increasing Infection intervals involved Kaplan–Meier Level male male serum testosterone men modeling multivariable Cox regression negativity Oxygen administration pandemic positive COVID-19 Predictive preliminary finding randomized trials Ratio reduced risk factor serum subsequent susceptibility Testing Testosterone the log-rank test total testosterone viral clearance viral infections viral positivity duration [DOI] 10.3390/diagnostics11040581 PMC 바로가기 [Article Type] Article
Risk factors for mortality in hospitalized patients with COVID-19 from three hospitals in Peru: a retrospective cohort studyResearch Article Published on 2021-03-192022-10-31 Journal: F1000Research [Category] COVID-19, SARS, [키워드] 95% CI 95% confidence interval adjusted Admission Adults age average calculated Care carried cohort study Comorbidity country COVID-19 diagnosis of COVID-19 evaluate evaluated Factor first stage functions group hazard hospital Hospitalized hospitalized patient laboratory parameter Latin America less male Mortality Older oxygen saturation pandemic patients hospitalized reduce mortality regression analysis retrospective cohort study risk risk factor SARS-CoV-2 Sociodemographic Symptom Symptoms the mean Treatment variables with COVID-19 [DOI] 10.12688/f1000research.51474.1 PMC 바로가기 [Article Type] Research Article
The networks of m 6 A-SARS-CoV-2 related genes and immune infiltration patterns in idiopathic pulmonary fibrosisResearch Paper Published on 2021-03-152022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, SARS, [키워드] Algorithm Analysis association cells cellular characteristic CIBERSORT Cohort contribute coronavirus disease correlation COVID-19 COVID-19 infection COVID-19 pandemic Cox model dataset develop Diseases evaluated Gene Expression Gene Expression Omnibus gene expression pattern genetic link hazard identify Idiopathic pulmonary fibrosis immune immune cells immune infiltration immune response infiltration IPF Lung disease Methylation N6-methyladenosine operator Pathways patients Pearson correlation poor prognosis Prognosis pulmonary fibrosis regulated reported Research RNA modification SARS-CoV-2 SARS-COV-2 infection similarity tissue Treatment was obtained was performed was used were used [DOI] 10.18632/aging.202725 PMC 바로가기 [Article Type] Research Paper