Postmortem diagnosis of COVID-19: Antemortem challenges of three cases at the 37 Military Hospital, Accra, GhanaOriginal Research Published on 2020-11-032022-10-28 Journal: African Journal of Laboratory Medicine [Category] COVID-19, [키워드] Accuracy acute respiratory syndrome Analysis Antemortem Autopsy Clinical symptoms close contact collected conducted Consistency Contact tracing coronavirus coronavirus disease COVID-19 COVID-19 case COVID-19 cases COVID-19 testing Department dependent on Diagnosis disease Duration of infection Factors false-negative Ghana histopathological histopathological finding initial laboratory result lung modifying factors nasopharyngeal Nasopharyngeal swab objective observation outcome Pathogenesis performed polymerase chain positive Postmortem postmortem diagnosis required respiratory Result rRT-PCR SARS-CoV-2 tested [DOI] 10.4102/ajlm.v9i1.1290 PMC 바로가기 [Article Type] Original Research
COVID-19 and Liver Damage: Narrative Review and Proposed Clinical Protocol for Critically ill Pediatric PatientsReview Article Published on 2020-11-022022-10-31 Journal: Clinics [Category] COVID-19, MERS, SARS, [키워드] ALT/AST both virus C-reactive protein case sery Characteristics clinical coronavirus COVID-19 COVID-19 patient Critically ill CRP described direct viral infection Drug-induced liver injury exacerbated Follow-up genomic sequence histopathological impairment include Infection Inflammatory inflammatory markers Inflammatory response lesions liver Liver damage liver enzyme management MERS-CoV narrative Necrosis pathophysiological mechanism pediatric Pediatric case periportal pro-calcitonin protocol raised respiratory symptom retrospective cohort review SARS-CoV SARS-CoV-2 SARS-CoV-2 infections shown Surveillance syndrome the SARS-CoV-2 with COVID-19 [DOI] 10.6061/clinics/2020/e2250 PMC 바로가기 [Article Type] Review Article
A structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infectionArticle Published on 2020-11-012022-10-29 Journal: Placenta [Category] COVID-19, MERS, SARS, [키워드] 95% CI acute respiratory syndrome association Care categorise Cluster collaboration confidence control group coronavirus COVID COVID-19 criteria demonstrated Evidence examined fetal generalisability highly pathogenic histopathological Histopathology inclusion criteria Infant Infection infection with SARS-CoV-2 Inflammation Inflammatory interval lack lesion lesions Limited majority MERS MERS-CoV Middle East morphology Neonate Novel coronavirus number of sample occur pandemic pathology Placenta placental positive Pregnancy reliability reported respiratory syndrome coronavirus SARS-CoV-1 SARS-CoV-1 infection SARS-CoV-2 SARS-COV-2 infection tested Transmission Vascular vertical transmission Wuhan, China [DOI] 10.1016/j.placenta.2020.08.018 PMC 바로가기 [Article Type] Article
A clinical, histopathological and laboratory study of 19 consecutive Italian paediatric patients with chilblain-like lesions: lights and shadows on the relationship with COVID-19 infectionchilblain-like 병변을 가진 19명의 연속 이탈리아 소아 환자에 대한 임상, 조직 병리학 및 실험실 연구: COVID-19 감염과의 관계에 대한 빛과 그림자Article Published on 2020-11-012022-09-11 Journal: Journal of the European Academy of Dermatology and [Category] SARS, 유전자 메커니즘, 치료기술, 치료법, [키워드] Acral anomalies Autoimmune disease Autoimmune diseases basal layer Blood borderline Capillaries Characteristics chilblain children clinical evaluation Coagulation COVID-19 COVID-19 infection COVID-19 pandemic dermis direct immunofluorescence electron microscopy epidermal finger flu-like symptom flu-like symptoms heel histopathological Histopathology hypodermis IgA IgG immunofluorescence increasingly Infection Informed consent Italian Laboratory lesion lesions Major majority mechanism Microscopy mucin Nasopharyngeal swab nucleocapsid protein oedema paediatric patient papillary dermis Pathogenesis pathological finding Patient patients perivascular positive Protein recruited reported RT-PCR S1 domain SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid SARS-CoV-2 spike protein selected serology serology testing skin lesion skin lesions skin manifestation Spike protein Swab thrombi vessel with COVID-19 [DOI] 10.1111/jdv.16682 PMC 바로가기 [Article Type] Article
Assessments of different inactivating reagents in formulating transmissible gastroenteritis virus vaccineResearch Published on 2020-10-232022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] β-propiolactone assessment Binary-ethylenimine cause caused CD4 CD8 cellular cellular immunity characterized control group demonstrated diarrhea Effect effective ELISA evaluated experimental group flow cytometry formaldehyde gastroenteritis group highest histopathological Histopathology Humoral immunity IFN-γ IgG IL-4 immunization inactivated Inactivated vaccine indicated induce Infection lymphocyte macroscopic mice Mortality pathological change pathology performed Peripheral blood positive rate produced proliferation reagent Result spleen subset T lymphocyte TGEV the disease transmissible gastroenteritis virus Transmissible gastroenteritis virus (TGEV) Vaccine virus vomiting [DOI] 10.1186/s12985-020-01433-8 PMC 바로가기 [Article Type] Research
Protection measures against SARS-CoV-2 infection for cytopathology and histopathology laboratories personnel: practical recommendations세포 병리학 및 조직 병리학 실험실 직원을 위한 SARS-CoV-2 감염에 대한 보호 조치: 실제 권장 사항Review Published on 2020-10-012022-09-11 Journal: Romanian journal of morphology and embryology = Re [Category] MERS, SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 body fluid body fluids clinical laboratories coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cytological cytopathology Emergency Departments equipment frozen section group handling hazard healthcare worker Healthcare workers high risk histopathological Histopathology hospital inactivation information Laboratory measure medical staff New coronavirus pandemic Pathogens pathology Patient patients protection Protective radiology departments recommendation respiratory restraint Romania SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus smear specimen surgical this new coronavirus transmission route Transmission routes [DOI] 10.47162/RJME.61.4.09 PMC 바로가기 [Article Type] Review
Imaging Diagnostics and Pathology in SARS-CoV-2-Related DiseasesReview Published on 2020-09-222022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] acute respiratory syndrome addition Algorithm applied artificial intelligence association Chinese Clinical data concerning Coronavirus-2 diagnostic procedure drug effort evaluated global pandemic histopathological imaging imaging diagnostic In vitro studies in vivo Infection Interpretation Invasion kidney lung mechanisms nuclear organ outbreak pandemic pathology Patient physician Pneumonia protocol provided Replication reported SARS-CoV-2 Scientific community Support the SARS-CoV-2 Treatment ultrastructure Vascular WHO World Health Organization Wuhan [DOI] 10.3390/ijms21186960 PMC 바로가기 [Article Type] Review
Are chilblains a skin expression of COVID-19 microangiopathy?chilblains는 COVID-19 미세혈관병증의 피부 표현입니까?Article Published on 2020-09-012022-09-12 Journal: Journal of thrombosis and haemostasis : JTH [Category] 진단, [키워드] Abstract chilblain chilblains COVID-19 expression histopathological histopathological findings hypercoagulable Hypercoagulable state Microthrombosis thrombotic thrombotic vasculopathy. [DOI] 10.1111/jth.15008 PMC 바로가기 [Article Type] Article
Digital pathology and computational image analysis in nephropathology Reviews Published on 2020-08-262022-10-05 Journal: Nature reviews. Nephrology [Category] 바이오마커, [키워드] acquisition Analysis applied approach clinically consortia data extraction Digital disease disease categories domains ecosystem generate histopathological homogeneous identify individual information Interpretation Kidney diseases machine-learning management oncology pathology Patient progression renal Repository risk shifting subject supported tissue Treatment [DOI] 10.1038/s41581-020-0321-6 [Article Type] Reviews
Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman PrimatesOriginal Article Published on 2020-07-282022-11-01 Journal: The New England Journal of Medicine [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Analysis antibody Antigen BAL BAL fluid CD4 T-cell CD8 T-cell responses changes in coronavirus coronavirus disease detectable Dilution dose eight evaluate geometric mean titer groups histopathological Inflammation inhibitory lower airway lower airways lung mRNA-1273 mRNA-1273 vaccine nasal swab Neutralizing activity pathologic performed polymerase chain Prevent primate quantification Replication response Result robust SARS-CoV-2 serum Seven specimen specimens Spike protein T-cell T-cell Response Th2 type 1 helper undetectable Vaccine vaccine group viral genome viral replication were assessed [DOI] 10.1056/NEJMoa2024671 PMC 바로가기 [Article Type] Original Article