Controlled branched-chain amino acids auxotrophy in Listeria monocytogenes allows isoleucine to serve as a host signal and virulence effectorListeria monocytogenes의 조절된 분지쇄 아미노산 영양요구성은 이소류신이 숙주 신호 및 독성 효과기 역할을 할 수 있도록 합니다.Research Article Published on 2018-03-122022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activate adaptation amino acids Bacteria Bacterial pathogens BCAA BCAA biosynthesis BCAA biosynthesis genes branched-chain amino acid branched-chain amino acids CodY conditions Control Controlled deficiency dependent on downstream gene downstream genes Evidence expression function Gene regulation highlight Host Infection intracellular pathogen isoleucine L . monocytogene Listeria Listeria monocytogene Listeria monocytogenes mammalian cell mechanism metabolic pathway metabolic pathways metabolism metabolites occur pathogen pathogenic Pathogens regulate Regulation represse respond restrict Rli60 saprophyte switching transcribed transition Trigger triggers upregulated upstream virulence virulence gene virulence genes virulent while [DOI] 10.1371/journal.pgen.1007283 PMC 바로가기 [Article Type] Research Article
Honing in on enteric fever장티푸스에 집중하다Article Published on 2014-07-012024-07-30 Journal: eLife [Category] 살모넬라증, [키워드] Enteric fever Human mass spectrometry metabolites salmonella paratyphi a Salmonella Typhi typhoid [DOI] 10.7554/eLife.03545 PMC 바로가기
Salmonella Typhi and Salmonella Paratyphi A elaborate distinct systemic metabolite signatures during enteric fever장티푸스 동안 살모넬라 타이피와 살모넬라 파라티피 A는 독특한 전신 대사체 서명을 나타낸다.Article Published on 2014-06-052024-07-31 Journal: eLife [Category] 살모넬라증, [키워드] Enteric fever Human mass spectrometry metabolites salmonella paratyphi a Salmonella Typhi typhoid [DOI] 10.7554/eLife.03100 PMC 바로가기
Global host metabolic response to Plasmodium vivax infection: a 1 H NMR based urinary metabonomic study플라스모디움 비박스 감염에 대한 전신 대사 반응: 1H NMR 기반의 소변 대사체 연구Research Published on 2011-12-232024-08-14 Journal: Malaria Journal [Category] 말라리아, [키워드] Biomarker metabolites metabonomics NMR Plasmodium vivax [DOI] 10.1186/1475-2875-10-384 PMC 바로가기 [Article Type] Research