Sofosbuvir as a potential alternative to treat the SARS-CoV-2 epidemicArticle Published on 2020-06-092022-10-04 Journal: Scientific Reports [Category] SARS, 변종, 치료제, [키워드] Antiviral approved conserved coronavirus Epidemic hepatitis C virus Infection infections Molecular medicine Pathogens polymerase residue SARS-CoV SARS-CoV-2 sofosbuvir the SARS-CoV-2 treat Treatment Vaccine Virology viruses [DOI] 10.1038/s41598-020-66440-9 PMC 바로가기 [Article Type] Article
Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelago게놈 차원의 DNA 메틸화 및 유전자 발현 패턴은 인도네시아 군도 전체의 유전적 조상과 환경적 차이를 반영합니다.Research Article Published on 2020-05-262022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] admixture Analysis capture complex country CpG dataset differential expression differentially expressed disease Diversity DNA methylation driven by environmental factor European examined excluded expression expression level expression levels Gene Expression gene expression pattern Genetic genomic healthy individuals highlighting Host human populations humans identify immune function Immunity implication in healthy individuals individual Indonesia Infectious disease introgression involved island majority Methylation molecular Molecular medicine molecular pattern molecular phenotype Neanderthal New pathway Pathways Phenotypes Population promoter robust selective pressure Sequencing Sumba tested Transcription tropical understanding Variation [DOI] 10.1371/journal.pgen.1008749 PMC 바로가기 [Article Type] Research Article
A suspicious role of interferon in the pathogenesis of SARS-CoV-2 by enhancing expression of ACE2Research Highlight Published on 2020-05-212022-10-29 Journal: Signal Transduction and Targeted Therapy [Category] COVID-19, MERS, SARS, [키워드] ACE2 expression Infection interferon Molecular medicine pathogenesis of SARS-CoV-2 [DOI] 10.1038/s41392-020-0185-z PMC 바로가기 [Article Type] Research Highlight
Rapid detection of terbinafine resistance in Trichophyton species by Amplified refractory mutation system-polymerase chain reaction트리코피톤 종에서 증폭된 불활성 돌연변이 시스템-중합효소 연쇄 반응에 의한 테르비나핀 내성의 신속한 검출Article Published on 2020-01-282024-07-28 Journal: Scientific Reports [Category] 백선증, [키워드] Fungal genetics Molecular medicine [DOI] 10.1038/s41598-020-58187-0 PMC 바로가기 [Article Type] Article
Differential IL-17A response to S. pneumoniae in adenoid tissue of children with sleep disordered breathing and otitis media with effusion수면 장애 호흡 및 삼출성 중이염이 있는 아동의 아데노이드 조직에서 S. pneumoniae에 대한 차별적 IL-17A 반응Article Published on 2019-12-272024-07-31 Journal: Burma Med J [Category] 폐렴구균 감염증, [키워드] Lymphocyte activation Molecular medicine Paediatric research [DOI] 10.1038/s41598-019-56415-w PMC 바로가기 [Article Type] Article
Natural Product Inspired Novel Indole based Chiral Scaffold Kills Human Malaria Parasites via Ionic Imbalance Mediated Cell Death자연 유래 제품에서 영감을 받은 새로운 인돌 기반의 키랄 스캐폴드가 이온 불균형 매개 세포 사멸을 통해 인간 말라리아 기생충을 죽인다.Article Published on 2019-11-282024-08-11 Journal: Burma Med J [Category] 말라리아, [키워드] Infection Molecular medicine Parasite biology [DOI] 10.1038/s41598-019-54339-z PMC 바로가기 [Article Type] Article