A Postcard From Italy: Challenges and Psychosocial Resources of Partners Living With and Without a Chronic Disease During COVID-19 EpidemicPsychology Published on 2020-12-112022-10-31 Journal: Frontiers in Psychology [Category] COVID-19, [키워드] addition adopted challenge changed chronic chronic disease Chronic illness COVID-19 cross-sectional global pandemic health condition healthy individual Italian Italian population less lockdown new virus outbreak pandemic partner Postcard protective role Psychological well-being Psychosocial Quality of life relational well-being resource Result shown Stress Stressor subject the epidemic WHO World Health Organization [DOI] 10.3389/fpsyg.2020.567522 PMC 바로가기 [Article Type] Psychology
A potential hypothesis for 2019-nCoV infection therapy through delivery of recombinant ACE2 by red blood cell-hitchhikingHypothesis Published on 2020-12-072022-10-30 Journal: Journal of Biological Research [Category] COVID-19, [키워드] 2019-nCoV 2019-nCoV infection 2019-nCoV infections ACE2 acting Angiotensin II approach Blood blood circulation bloodstream caused cellular country decrease Diseases drug delivery Epidemic Hypothesis increase Infectious disease investigated liver lung lung failure Lungs Nanoparticles neutralize novel outbreak proportion PROTECT protective role RBC RBC hitchhiking receptor recombinant ACE2 responsible reticuloendothelial system Serum level severe respiratory disease soluble ACE2 spleen Spread The 2019-nCoV Therapeutic approach therapy variety virus [DOI] 10.1186/s40709-020-00129-y PMC 바로가기 [Article Type] Hypothesis
On Cancer, COVID-19, and CT Scans: A Monocentric Retrospective StudyArticle Published on 2020-12-042022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute respiratory syndrome affected age analyzed Asymptomatic Bergamo Cancer cardiovascular comorbidities chest CT scan Computed tomography coronavirus coronavirus disease correlation COVID-19 COVID-19 infection COVID-19 outbreak COVID-19 pandemic CT scan diagnose Diagnosis diagnosis of COVID-19 disease disease severity heterogeneous Immunosuppression incidence Infection Italy Mild symptom mildly symptomatic patients mortality rate nasopharyngeal swabbing oncological patients Patient patients previous study Prognosis protective role Result RT-PCR RT-PCR test SARS-CoV-2 SARS-COV-2 infection severe disease Sex smoking suggested symptomatic patient treated Treatment unit [DOI] 10.3390/jcm9123935 PMC 바로가기 [Article Type] Article
Evidence for treatment with estradiol for women with SARS-CoV-2 infectionResearch Article Published on 2020-11-252022-10-28 Journal: BMC Medicine [Category] COVID-19, SARS, [키워드] 95% CI ACE2 acute respiratory syndrome administration age age and gender Analysis analyzed both sexes cellular entry changed coronavirus coronavirus disease COVID-19 COVID-19 cohort COVID-19 patient death Effect effective Electronic health record estradiol estradiol therapy expression Factor fatality Fatality rate female hazard ratio Hormone treatment human Angiotensin-converting enzyme incidence Infection influence International Kaplan-Meier survival curve men outcomes pre-menopausal women Predictive Primary outcome propensity score matching Prospective Study protective role Protein receiving reduced Result Retrospective study risk risk of COVID-19 risk of infection SARS-CoV-2 SARS-COV-2 infection Sex significantly higher sub-cohort supplementary material susceptibility therapeutic therapy Treatment was performed while women [DOI] 10.1186/s12916-020-01851-z PMC 바로가기 [Article Type] Research Article
Antecedent Administration of Angiotensin-Converting Enzyme Inhibitors or Angiotensin II Receptor Antagonists and Survival After Hospitalization for COVID-19 SyndromeObservational Study Published on 2020-11-172022-10-05 Journal: Journal of the American Heart Association [Category] 임상, [키워드] 95% CI ACE-2 ACEi acute respiratory syndrome administration affected age Analysis Angiotensin II angiotensin-converting enzyme inhibitor angiotensin-converting enzyme-2 angiotensin‐converting enzyme inhibitor angiotensin‐converting enzyme‐2 antagonist antecedent ARB cardiovascular risk congestive heart failure Coracle coronavirus coronavirus disease COVID-19 COVID‐19 death Diabetes Mellitus enzyme groups Hospitalization Hospitalized human cells hypertension in-hospital mortality inhibitor Italy Mortality Odds ratio Older overall mortality Patient patients patients hospitalized Primary outcome protective role receptor reduced reduced risk Region renin‐angiotensin converting enzyme inhibitor. Result SARS-CoV-2 SARS‐CoV‐2 Sex smoking status trend upregulation while with COVID-19 [DOI] 10.1161/JAHA.120.017364 PMC 바로가기 [Article Type] Observational Study
The protective role of life satisfaction, coping strategies and defense mechanisms on perceived stress due to COVID-19 emergency: A chained mediation modelResearch Article Published on 2020-11-132022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Analysis analyzed approach consequence contribute coping Coping strategy Coronavirus disease-19 correlation COVID-19 COVID-19 pandemic Defense distress emotional Factor help Intervention inventory Italian item life lockdown measure mechanism mediation model mental health Orientation outcome pandemic participant pathway Perceived stress Perceived Stress Scale Perspective positive attitude problem PROTECT Protective protective role Research Risk factors Satisfaction scale variable [DOI] 10.1371/journal.pone.0242402 PMC 바로가기 [Article Type] Research Article
Possible protective role of 17β-estradiol against COVID-19Article Published on 2020-11-082022-10-30 Journal: Journal of allergy and infectious diseases [Category] COVID-19, [키워드] 17β-estradiol ACE2 acute respiratory distress all age groups angiotensin-converting enzyme 2 appear ARDS binding cause cells coronavirus disease COVID-19 develop down-regulate fatality infect cell Medical conditions men Older Patient plasma membrane priming protease Protective protective role Protein protein expression RAAS SARS-CoV-2 SARS-CoV-2 spike protein serine 2 severe complication Sex difference syndrome therapeutic TMPRSS2 transmembrane virus WHO women World Health Organization worldwide pandemic [DOI] 10.46439/allergy.1.010 PMC 바로가기 [Article Type] Article
Could MEFV mutation carriage status have a protective role for COVID-19 pandemic?MEFV 돌연변이 운반 상태가 COVID-19 전염병에 대한 보호 역할을 할 수 있습니까?Article Published on 2020-11-012022-09-11 Journal: Medical Hypotheses [Category] 변종, [키워드] COVID-19 MEFV Mutation protective role [DOI] 10.1016/j.mehy.2020.109889 PMC 바로가기 [Article Type] Article
Prioritizing potential ACE2 inhibitors in the COVID-19 pandemic: Insights from a molecular mechanics-assisted structure-based virtual screening experimentResearch article Published on 2020-11-012022-10-05 Journal: Journal of molecular graphics & modelling [Category] SARS, 신약개발, [키워드] ACE2 approved Cell clinically cofactor Contact COVID-19 COVID-19 outbreak Critical disease docked drug drug candidate drug library drug repositioning drugs Entry inhibitor enzyme experiment exterior generate human ACE2 in silico inhibitor inhibitors Initially insight introduced Ligand ligands mechanism membrane-bound molecular molecular docking peptide protective role receptor residue SARS-CoV-2 screened shifting therapeutic therapeutic target Virtual screening [DOI] 10.1016/j.jmgm.2020.107697 [Article Type] Research article
Should ACE2 be given a chance in COVID-19 therapeutics: A semi-systematic review of strategies enhancing ACE2Research article Published on 2020-11-012022-10-05 Journal: European journal of pharmacology [Category] 신약개발, [키워드] absence ACE ACE2 acute respiratory syndrome analysed Ang (1–7) Angiotensin converting enzyme-2 Angiotensin II antiviral therapy bind Cardiopulmonary Corona virus COVID-19 COVID-19 disease COVID-19 pathogenesis death diabetes downregulation downstream drug effective enzyme human cell Loss modulation other organs pathophysiological Pathways progression protective effect protective role Protein pulmonary epithelial cell pulmonary system RAAS receptor SARS-CoV-2 stimulate symptomatic therapeutic Treatment Vaccine virus [DOI] 10.1016/j.ejphar.2020.173545 [Article Type] Research article