severe cases

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alteration antibodies autoantibodies autoantibody caused change circulating leukocyte circulating leukocytes Control coronavirus coronavirus disease Coronavirus disease 2019 correlated Course COVID-19 Critical Critical disease dendritic cell description diagnosed disease course disease pathogenesis Effect elevated epitope evaluated Evidence evidence of expressed expression functional healthy controls help IFNs immune immune system Immunoglobulin in some increased expression individual individuals with COVID-19 inhibitory receptor interferon interferon response interferons ISG lack LAIR1 leukocyte leukocytes longitudinal mechanisms moderate disease monocyte Monocytes mononuclear cell mononuclear cells myeloid cell myeloid cells Patient patients with COVID-19 Peripheral blood Peripheral blood mononuclear cells peripheral blood samples Population Prevalence producing receptor reduced respiratory response SARS-CoV-2 severe acute respiratory syndrome Coronavirus Severe case severe cases severe disease severity single-cell Single-cell transcriptomics subset Support systemic impact systemic impacts the disease Transcriptome transcriptome sequencing transcriptomics turn Type type I Type I IFN type I interferon type I interferons
[DOI] 10.1126/scitranslmed.abh2624 PMC 바로가기 [Article Type] Research Article