COVID-19 Vaccination within the Context of Reactogenicity and Immunogenicity of ChAdOx1 Vaccine Administered to Teachers in Poland폴란드 교사에게 투여된 ChAdOx1 백신의 반응성 및 면역원성의 맥락에서 COVID-19 백신 접종Article Published on 2022-03-062022-09-10 Journal: International Journal of Environmental Research an [Category] MERS, SARS, 진단, 치료기술, [키워드] adverse effects Adverse reaction Adverse reactions age All participant All participants anti-RBD Anti-RBD IgG Antibody Response ChAdOx1 ChAdOx1 vaccine ChAdOx1-S chills Context COVID-19 demonstrated detectable determinants dose dosing interval Efficacy ENhance female first dose headache immunogenicity immunologic response immunologic responses individual Infection interval malaise male mRNA multivariate logistic regression offered Older participant Participants Poland predictor RBD reactogenicity Receptor-binding domain Region reported required SARS-CoV-2 SARS-COV-2 infection Serological testing Side effect Side effects Support teacher teachers the mean the median the receptor-binding domain Tolerability uninfected Vaccine were measured [DOI] 10.3390/ijerph19053111 PMC 바로가기 [Article Type] Article
Inference in epidemiological agent-based models using ensemble-based data assimilationResearch Article Published on 2022-03-042022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] age attribute Buenos Aires compartmental model complex Contact Contact tracing COVID-19 disease disease spread epidemiological epidemiological data Evolution experiment feature individual individual level Infection Inference information Interaction joint Kalman filter methodology MONITOR observation parameter parameters Population provided raise representing risk Schools statistical the mean [DOI] 10.1371/journal.pone.0264892 PMC 바로가기 [Article Type] Research Article
Estimation of Serial Interval and Reproduction Number to Quantify the Transmissibility of SARS-CoV-2 Omicron Variant in South Korea한국에서 SARS-CoV-2 오미크론 변이체의 전염성을 정량화하기 위한 일련 간격 및 복제 수 추정Article Published on 2022-03-042022-09-11 Journal: Viruses [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed B.1.1.529 children Community coronavirus CrI distribution estimate estimation interval likelihood Local maximum likelihood estimation number omicron Omicron variant outbreak predominant public health measures reconstructed reduce reproduction Reproduction number risk SARS-CoV-2 Serial interval severe acute respiratory syndrome Coronavirus significantly shorter South Korea Standard deviation the mean Transmissibility Transmission variant [DOI] 10.3390/v14030533 PMC 바로가기 [Article Type] Article
Clinical findings, viral load, and outcomes of COVID-19: Comparison of patients with negative and positive initial chest computed tomographyCOVID-19의 임상 소견, 바이러스 부하 및 결과: 초기 흉부 컴퓨터 단층 촬영 음성 및 양성 환자의 비교Comparative Study Published on 2022-03-032022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] addition Admission age AUC characteristic Chest computed tomography Chest CT clinical Clinical characteristics Clinical data Clinical findings confidence interval COVID-19 CRP level Ct value Cutoff Diagnosis Efficacy evaluated examined Fever help Hospital stay initial intensive care intensive care unit admission male mean hospital stay negative and positive Odds ratio Older outcome Patient patients Pneumonia positive receiver operating characteristic report ROC significantly significantly higher tested the mean therapy threshold value Viral load viral loads [DOI] 10.1371/journal.pone.0264711 PMC 바로가기 [Article Type] Comparative Study
Development of an Adeno-Associated Virus-Vectored SARS-CoV-2 Vaccine and Its Immunogenicity in Mice아데노 관련 바이러스 벡터화 SARS-CoV-2 백신의 개발 및 마우스에서의 면역원성Article Published on 2022-03-032022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 치료기술, [키워드] AAV9 adeno-associated virus administration BALB/c mice Cell culture cell culture supernatant development dimeric evaluated expressed expressing Genome HeLa cell HeLa cells immune immunization immunized immunogenicity Intramuscular injection linker long term long term protection mice murine model N-terminus nasal Neutralizing antibodies neutralizing antibody New coronavirus Novel coronavirus outbreak peptide pseudovirus purified Q-PCR RBD Receptor binding domain recombinant RBD protein S protein SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 vaccine sera signal peptide Spike protein the mean the SARS-CoV-2 Vaccine vaccine candidate vectored vaccine virus was determined [DOI] 10.3389/fcimb.2022.802147 PMC 바로가기 [Article Type] Article
Switch from Olanzapine Long-Acting Injectable to its Oral Equivalent during COVID-19 Pandemic: a Real World Observational StudyObservational Study Published on 2022-03-022022-10-04 Journal: The Psychiatric Quarterly [Category] MERS, 임상, [키워드] Administered age caused clinical Compliance conducted COVID-19 COVID-19 pandemic Diseases Effect equivalent Evolution gluteal injection intramuscular lack Long-acting antipsychotic medication NEUROLOGY Olanzapine Olanzapine pamoate oral Patient progression Psychiatric psychiatric condition Relapse Romania Schizophrenia sudden switch switching the mean the patient Treatment [DOI] 10.1007/s11126-021-09924-9 PMC 바로가기 [Article Type] Observational Study
High-titre methylene blue-treated convalescent plasma as an early treatment for outpatients with COVID-19: a randomised, placebo-controlled trialRandomized Controlled Trial Published on 2022-03-012022-10-04 Journal: The Lancet. Respiratory Medicine [Category] COVID19(2023년), SARS, 바이오마커, 임상, 치료법, [키워드] 1:1 age Analysis anti-SARS-CoV-2 IgG assigned baseline convalescent plasma COVID-19 COVID-19 vaccine crowdfunding did not reduce double-blind early treatment Efficacy eligible Endpoint enrolment Euroimmun Evidence experimental group experimental intervention for inclusion Grifols health-care hospitalisation in viral incidence intention-to-treat population intravenous IQR less log Methylene Mild mild COVID-19 symptom monitoring board multicentre Nasopharyngeal swab occurred Older Outpatient participant Patient Placebo placebo-controlled trial plasma Prevent progression random assignment randomisation randomised Randomly receive recommendation reduce Registered reported risk saline solution SARS-CoV-2 viral load Serious Adverse Event severe disease Spain Stratification Support symptom duration the mean Thromboembolic event titre Treatment Trial Viral load was done web-based system with COVID-19 [DOI] 10.1016/S2213-2600(21)00545-2 PMC 바로가기 [Article Type] Randomized Controlled Trial
Evaluation of bacterial agents isolated from endotracheal aspirate cultures of Covid-19 general intensive care patients and their antibiotic resistance profiles compared to pre-pandemic conditions코로나19 일반 중환자실 환자의 기관내 흡인 배양액에서 분리한 세균성 물질의 평가와 전염병 이전 상태와 비교한 항생제 내성 프로파일Article Published on 2022-03-012022-09-11 Journal: Microbial pathogenesis [Category] SARS, 치료기술, [키워드] Acinetobacter age amoxicillin Antibiotic resistance Antibiotics antimicrobial Antimicrobial stewardship Bacterial bacterial co-infection Candida cefepime Ceftazidime ciprofloxacin clavulanic acid clinical Clinical outcome colistin condition Course COVID-19 pandemic Critically ill Critically ill patient critically ill patients Culture cultures died ertapenem Escherichia coli evaluated Gender growth ICU imipenem increase increase in infected with SARS-CoV-2 intensive care intensive care follow-up intensive care patient intensive care unit Klebsiella pneumoniae levofloxacin meropenem microorganism more difficult Mortality no significant difference nosocomial Nosocomial pneumonia P. aeruginosa pandemic Patient patients hospitalized piperacillin piperacillin-tazobactam Pneumonia pneumoniae Prevalence prevalent profile Pseudomonas aeruginosa SARS-CoV-2 Secondary infection secondary infections shown significant difference Staphylococcus aureus statistically significant statistically significant difference strain Strains tazobactam the mean tigecycline tobramycin Treatment VAP Ventilator-associated pneumonia while [DOI] 10.1016/j.micpath.2022.105409 PMC 바로가기 [Article Type] Article
Evaluation of a rapid-antigen test for COVID-19 in an asymptomatic collective : A prospective study무증상 집단에서의 코로나19 신속항원검사 평가 : 전향적 연구Article Published on 2022-03-012022-09-11 Journal: Wiener medizinische Wochenschrift (1946) [Category] SARS, 치료기술, [키워드] Antigen antigen detection Asymptomatic average carried Chain Reaction confidence interval COVID-19 COVID-19 patient COVID-19 patients cycle threshold District early stage early stages evaluate hospital mass Mass screening over performed point of care point-of-care testing polymerase chain polymerase chain reaction positive positive result Prospective Study Rapid Rapid antigen tests Real-Time Reverse Transcription Polymerase Chain Reaction Real-time reverse transcription polymerase chain reaction. resource reverse transcription reverse transcription polymerase chain reaction Roche Diagnostics RT-PCR RT-PCR tests SARS-CoV‑2 sensitivity Sensitivity and specificity significant increase specificity Swab Symptom tested the mean treated Viral load viral loads was done [DOI] 10.1007/s10354-021-00883-1 PMC 바로가기 [Article Type] Article
Can FeNO be a biomarker in the post-COVID-19 patients monitoring?FeNO는 코로나19 이후 환자 모니터링에서 바이오마커가 될 수 있습니까?Article Published on 2022-03-012022-09-11 Journal: Respiratory medicine [Category] MERS, SARS, 바이오마커, [키워드] 95% CI Asthma Biomarker bronchial asthma Can clinical manifestation clinical manifestations Consistency control group Corticosteroid Corticosteroids COVID-19 disease onset enrolled FeNO healthy subject healthy subjects healthy volunteer Hospitalized Hypothesis Inflammatory mean difference men nitric oxide Patient post-COVID-19 post-COVID-19 patient Post-COVID-19 patients reported statistically significant syndrome systemic corticosteroid systemic corticosteroids the mean treated women [DOI] 10.1016/j.rmed.2022.106745 PMC 바로가기 [Article Type] Article