SARS-CoV-2 and mitochondrial health: implications of lifestyle and ageingReview Published on 2020-11-092022-10-30 Journal: Immunity & Ageing : I & A [Category] COVID-19, [키워드] “cytokine storm” adaptive age cellular co-morbidity diabetes fatality functional Health healthy Host humans immune response immune system implication key factor maintain marker mitochondrial Mitochondrial function modulate new virus provide Replication SARS-CoV-2 Stress Support syndrome Treatment vaccine response virus [DOI] 10.1186/s12979-020-00204-x PMC 바로가기 [Article Type] Review
Shelter from the cytokine storm: pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly populationReview Published on 2020-11-062022-10-29 Journal: Seminars in immunopathology [Category] COVID-19, MERS, SARS, [키워드] age boost candidate clinical study clinical testing Comorbidities complex COVID-19 cytokine effective Effectiveness effort exacerbate Factor fraction help identify immune responses immune responsiveness immunopathological immunosenescence inflammaging lack marker mechanism Older older population overlap pharmacological treatments phenotype Prognosis recent response risk robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2 vaccine Systems biology tested vaccination vaccination efficacy Vaccination strategy Vaccine Vaccine development vaccine response virulence [DOI] 10.1007/s00281-020-00821-0 PMC 바로가기 [Article Type] Review
COVID-19 Vaccines Currently under Preclinical and Clinical Studies, and Associated Antiviral Immune ResponseReview Published on 2020-11-032022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] candidate caused clinical clinical trials Convalescent patients COVID-19 COVID-19 pandemic death determine develop effective Efficacy effort Human immune response impacted implication Infection Neutralizing antibodies Preclinical preclinical studies recovered COVID-19 patient response SARS-CoV-2 T-cell responses Vaccine vaccine candidate Vaccine development vaccine platform vaccine platforms vaccine response [DOI] 10.3390/vaccines8040649 PMC 바로가기 [Article Type] Review
T cell regeneration after immunological injury Reviews Published on 2020-10-232022-10-05 Journal: Nature reviews. Immunology [Category] 바이오마커, [키워드] adaptive approach benefit cause cell stress Chemotherapy clinical consequences consequence de novo Delayed ENhance immune immune function immune system Immunity immunological Immunosuppression increased risk individual Infection Injury malignancies outcome Patient promote Radiotherapy review T cell T cells therapeutic strategy thymic vaccine response [DOI] 10.1038/s41577-020-00457-z [Article Type] Reviews
Systematic analysis of infectious disease outcomes by age shows lowest severity in school-age childrenAnalysis Published on 2020-10-152022-10-29 Journal: Scientific Data [Category] Coronavirus, MERS, SARS, [키워드] Adults age Analysis assumed Bacterial Bacterial infection children Course COVID-19 pandemic dataset Diseases extreme groups Health immune function immune senescence implication Infection infections Infectious disease information lowest manifestation Older age outcome reached relative Resilience Risk factors severe disease severity Severity of disease systematic analysis Vaccine vaccine response viral infection [DOI] 10.1038/s41597-020-00668-y PMC 바로가기 [Article Type] Analysis
Cellular senescence as a potential mediator of COVID‐19 severity in the elderlyReview Published on 2020-09-212022-10-28 Journal: Aging Cell [Category] COVID-19, MERS, SARS, [키워드] accumulate advanced age alleviate association Biomarker cellular cellular senescence characterized complex Consequences contribute coronavirus disease COVID‐19 COVID‐19 patient Cytokine storm detrimental disease disease severity distress early phase Efficacy evaluate Factor functional growth Health identifying IMPROVE individual infect inflammatory reaction limit Lower respiratory tract lung failure mechanism novel Betacoronavirus Older Pathogenesis Prevent promote rising mortality risk SARS‐CoV‐2 SARS‐CoV‐2 infection second senescence senescent cell severe complication severity syndrome the disease therapy tissue damage Vaccinations Vaccine vaccine response [DOI] 10.1111/acel.13237 PMC 바로가기 [Article Type] Review
GWAS identifying HLA-DPB1 gene variants associated with responsiveness to hepatitis B virus vaccination in Koreans: Independent association of HLA-DPB1*04:02 possessing rs1042169 G – rs9277355 C – rs9277356 AArticle Published on 2019-11-012023-06-16 Journal: Journal of viral hepatitis [Category] B형 간염, [키워드] Hepatitis B virus HLA-DPB1 Korean vaccine response [DOI] 10.1111/jvh.13168
Pneumococcal vaccination responses in adults with subnormal IgG subclass concentrations성인에서 비정상 IgG 아형 농도에 대한 폐렴구균 백신 반응Research Article Published on 2019-08-202024-07-27 Journal: BMC Immunology [Category] 폐렴구균 감염증, [키워드] IgG subclasses pneumococcal Pneumovax®23 Primary Immunodeficiency vaccine response [DOI] 10.1186/s12865-019-0310-3 PMC 바로가기 [Article Type] Research Article
T Follicular Helper Cell Development and Functionality in Immune AgingArticle Published on 2019-02-222024-09-04 Journal: Clinical Science (London, England : 1979) [Category] 대상포진, [키워드] B cell antibody production Germinal center immunosenescence T cell differentiation T follicular regulatory cell vaccine response [DOI] 10.1042/CS20171157 PMC 바로가기 [Article Type] Article
Measurement and interpretation of Salmonella typhi Vi IgG antibodies for the assessment of adaptive immunityarticle Published on 2018-08-312024-09-01 Journal: Nursing Reports [Category] 살모넬라증, [키워드] Humoral immunodeficiency Immunoglobulin replacement Pneumococcal polysaccharide antigens pneumovax Typhim Vi vaccine response Vi polysaccharide antigen [Article Type] article