Outcomes of SARS-CoV-2 omicron infection in residents of long-term care facilities in England (VIVALDI): a prospective, cohort studyArticle Published on 2022-05-012022-11-16 Journal: The Lancet. Healthy longevity [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI age Alpha Analysis appear B.1.1.529 booster vaccination Care cohort study Course Coverage datasets death Department diagnosed disease severity eligible England excluded finding for inclusion hazard ratio Hospital admission indicated Infection investigated IQR Lateral flow device male median age MONITOR Mortality National National Health Service natural immunity NHS Observed Omicron variant outcome participant PCR Population positive positive PCR prospective cohort study PROTECT public health reduced reduction in resident risk risk of death SARS-CoV-2 SARS-CoV-2 test Sequencing severe disease severity Sex study period subset Surveillance tested unlikely Vaccine variant variants [DOI] 10.1016/S2666-7568(22)00093-9 PMC 바로가기
Prevalence of Micronutrient Deficiencies in Patients Hospitalized with COVID-19: An Observational Cohort StudyObservational Study Published on 2022-04-292022-10-05 Journal: Nutrients [Category] 임상, [키워드] 95% CI adjusted Admission age analyzed association B12 Clinical course Cohort composite endpoint coronavirus disease correlation correlation coefficient courses COVID-19 deficiencies deficiency eight Folic acid higher risk hospital hospital outcomes Hospitalized ICU in-hospital mortality intensive care IQR Logistic regression lower risk male Micronutrient micronutrients micronutrients. MOST older patient Patient Prevalence prevalent progression Research SARS-CoV-2 serum/plasma severe COVID-19 severe COVID-19 disease severe disease progression Treatment Vitamin vitamin A [DOI] 10.3390/nu14091862 PMC 바로가기 [Article Type] Observational Study
Associations between physical activity prior to infection and COVID-19 disease severity and symptoms: results from the prospective Predi-COVID cohort studyObservational Study Published on 2022-04-292022-10-05 Journal: BMJ Open [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI age approach Asymptomatic baseline chest pain cohort study collected COVID-19 COVID-19 disease severity COVID-19 infection cross-sectional disease severity dry cough effective Epidemiology fatigue female headache highest Hospitalised patients Illness severity Infection IQR lower risk Luxembourg mild illness moderate Patient physical activity prevalent Primary outcome public health questionnaire reduced risk reverse transcription-PCR SARS-COV-2 infection secondary outcome Self-reported symptoms severity severity of COVID-19 Sports Medicine Symptom Symptoms tested the disease the median Volunteer [DOI] 10.1136/bmjopen-2021-057863 PMC 바로가기 [Article Type] Observational Study
A randomized clinical trial of a booster dose with low versus standard dose of AZD1222 in adult after 2 doses of inactivated vaccines불활성화 백신 2회 투여 후 성인에서 AZD1222의 저용량 대 표준 용량의 추가 용량에 대한 무작위 임상 시험Randomized Controlled Trial Published on 2022-04-202022-09-11 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, [키워드] 95% CI Adults anti-S anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG. Anti-spike antibody Antibody titer ARMS AstraZeneca AZD1222 baseline booster booster dose ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine completion conducted CoronaVac CoronaVac vaccine delta variant dose double-blinded enrolled evaluate Fever geometric geometric mean geometric mean ratio Geometric means GMR GMRs healthy IgG immunogenicity inactivated Inactivated vaccine Infection IQR low dose low-dose median age median interval myalgia neutralization test neutralizing antibody Neutralizing antibody titer participant Prevent Randomized randomized clinical trial randomized, controlled trial RBD IgG reactogenicity receive recipient S-RBD SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine significantly lower Standard dose surrogate surrogate virus neutralization test sVNT systemic reactogenicity the SARS-CoV-2 variant Viral Viral particles virus neutralization test wild type [DOI] 10.1016/j.vaccine.2022.03.036 PMC 바로가기 [Article Type] Randomized Controlled Trial
Using high-resolution contact networks to evaluate SARS-CoV-2 transmission and control in large-scale multi-day events고해상도 접촉 네트워크를 사용하여 대규모 수일 이벤트에서 SARS-CoV-2 전송 및 제어 평가Article Published on 2022-04-122022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, [키워드] activities close contact collected Contact country Coverage Crew Delta delta variant evaluate event High-resolution influence Intervention IQR Mask mask mandate Mask mandates median Outbreaks per day rapid antigen test Rapid antigen tests reduce required risk SARS-CoV-2 transmission SARS-CoV-2 variant social contact the vaccine Transmission unique vaccination [DOI] 10.1038/s41467-022-29522-y PMC 바로가기 [Article Type] Article
Efficacy of convalescent plasma therapy in the patient with COVID-19: a randomised control trial (COPLA-II trial)COVID-19 환자에서 회복기 혈장 요법의 효능: 무작위 대조 시험(COPLA-II 시험)Clinical Trial Published on 2022-04-062022-09-12 Journal: BMJ Open [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] 1:1 48 hour adverse events allergic reaction Antibody titre Blood blood bank & Clinical improvement clinical outcomes collected conducted convalescent plasma Convalescent plasma therapy COVID-19 COVID-19 patient cytokine level D-dimer Efficacy Hospital admission hospitalisation in both group incidence initial IQR median median time Mortality no difference on mechanical ventilation outcome PaO participant Patient plasma proportion randomised randomised controlled trial reduction in SARS-CoV-2 antibody secondary severe COVID-19 patients study population the patient therapy TNF-α transfused Transfusion medicine Treatment treatment group Trial [DOI] 10.1136/bmjopen-2021-055189 PMC 바로가기 [Article Type] Clinical Trial
Clinical Features of Multisystem Inflammatory Syndrome in Children Associated with COVID-19 in Indonesia인도네시아 코로나19 관련 소아 다기관 염증 증후군의 임상적 특징Article Published on 2022-04-052022-09-11 Journal: Journal of tropical pediatrics [Category] COVID19(2023년), SARS, 치료기술, [키워드] activated Admitted Patient age Asian characteristics of patient children clinical Clinical course Clinical outcome clinical outcomes Coagulation coagulation factor collected data coronavirus disease Coronavirus disease 2019 country COVID-19 cross-sectional cross-sectional study diagnosed Diagnosis elevated highlight hospital Indonesia Inflammatory inflammatory markers intubation IQR male mechanical ventilation median age median time MIS-C Most patient Most patients neutrophil neutrophil counts non-survivor Non-survivors outcome parameter Patient patients positive prothrombin Prothrombin time reported required study period survivor syndrome tertiary referral hospital the median those who survived Treatment two groups Vasopressor vasopressors while White blood cells with COVID-19 [DOI] 10.1093/tropej/fmac025 PMC 바로가기 [Article Type] Article
Observational study on chest pain during the Covid-19 pandemic: changes and characteristics of visits to a Norwegian emergency department during the lockdownObservational Study Published on 2022-04-022022-10-04 Journal: BMC Emergency Medicine [Category] 임상, [키워드] Acute coronary syndrome age average change Characteristics chest pain collected COVID-19 Emergency emergency services Fewer patient Gender hospital impacted increase in initial IQR less lockdown moderate Myocardial infarction National normalized Norway Norway. observational study outbreak pandemic Patient patients presenting proportion remained severity Spread study period subsequent the median the patient Variation [DOI] 10.1186/s12873-022-00612-w PMC 바로가기 [Article Type] Observational Study
Improving vaccination coverage and offering vaccine to all school-age children allowed uninterrupted in-person schooling in King County, WA: Modeling analysisArticle Published on 2022-04-012022-11-16 Journal: Mathematical biosciences and engineering : MBE [Category] COVID19(2023년), SARS, 변종, [키워드] addition age age structured model Analysis analyzed benefit calibrated changes in children Coverage COVID-19 COVID-19 vaccination Critical dynamic Epidemic Epidemiology Health Hospitalization hospitalizations Improving Interaction IQR King limit mathematical mathematical modeling measure median modeling morbidity and mortality physical PPI predicted Prevent proportion provide Rapid reached reduce reducing reduction reported restored SARS-CoV-2 transmission SARS-CoV-2 variant School social distancing Social distancing measure Spread the epidemic trajectory USA vaccinate vaccination Vaccine variants of concern Washington [DOI] 10.3934/mbe.2022266 PMC 바로가기
Bacterial/fungal infection in hospitalized patients with COVID-19 in a tertiary hospital in the Community of Castilla y León, Spain스페인 카스티야 이 레온 지역 3차 병원에 입원한 COVID-19 환자의 박테리아/진균 감염Observational Study Published on 2022-04-012022-09-11 Journal: Enfermedades infecciosas y microbiologia clinica ( [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] Acinetobacter Acinetobacter baumannii Acinetobacter baumanniia Admission analyses Bacteremia Brote Coinfección Coinfection Comorbidities contribute contributed COVID-19 COVID-19 patients demographic determine diagnosed elevated English Factor hospital hospitalized patient hospitalized patients ICU ICU patient ICU Patients incidence increase Increases Infection intensive care unit interferon IQR Leukocytosis majority male median age men Mortality MOST multidrug-resistant multivariate logistic regression observational study outbreak pacientes hospitalizado pathogen Pathogens Patient patients Predictive predictor profile profiles pulmonary aspergillosis respiratory infections SARS-CoV-2 SARS-CoV-2 pneumonia Sobreinfección Spain Spanish Staphylococcus aureus Streptococcus pneumoniae superinfection Superinfections Tocilizumab urinary viral respiratory infection viral respiratory infections with COVID-19 [DOI] 10.1016/j.eimce.2022.02.002 PMC 바로가기 [Article Type] Observational Study