Deletion in the S1 Region of Porcine Epidemic Diarrhea Virus Reduces the Virulence and Influences the Virus-Neutralizing Activity of the Antibody InducedArticle Published on 2020-12-022022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] activity Amino acid antibody antigenicity cause caused Clinical sign Complete cross-neutralize Deletion diarrhea distribution domain Epidemic epidemic diarrhea Genome induced induces influence lower mortality Mortality neutralizing active occurred PEDV reduce Region S gene spike gene Spike protein Strains variant virulence virus virus-neutralizing [DOI] 10.3390/v12121378 PMC 바로가기 [Article Type] Article
Asymptomatic deep vein thrombosis in critically ill COVID-19 patients despite therapeutic levels of anti-Xa activity치료 수준의 항-Xa 활성에도 불구하고 중환자 COVID-19 환자의 무증상 심부 정맥 혈전증Comment Published on 2020-12-012022-09-11 Journal: Thrombosis research [Category] SARS, 치료기술, [키워드] anticoagulation Clinical sign Clinical signs COVID-19 patient Critically ill critically ill COVID-19 patients dose DVT occur Prevalence severe COVID-19 patients therapeutic thrombosis [DOI] 10.1016/j.thromres.2020.08.043 PMC 바로가기 [Article Type] Comment
Absence of SARS-CoV-2 infection in cats and dogs in close contact with a cluster of COVID-19 patients in a veterinary campusResearch article Published on 2020-12-012022-10-05 Journal: One Health [Category] Coronavirus, 유전자 메커니즘, [키워드] acute respiratory syndrome Anosmia antibody bats Blood canine Clinical sign close contact Cluster Community conditions coronavirus Coronavirus infection cough COVID-19 COVID-19 epidemiology COVID-19 pandemic COVID-19 patient cross-sectional detectable feline Fever host range immunoprecipitation index case infect Infection initial LIPS Luciferase immunoprecipitation system outbreak positive reported responsible SARS-CoV-2 SARS-COV-2 infection Self-isolation Spread tested the antibody response the disease virus with COVID-19 Wuhan, China [DOI] 10.1016/j.onehlt.2020.100164 [Article Type] Research article
Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infectionResearch Article Published on 2020-11-302022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] absence accompanied Activation Antiviral effect Brain caused CD4 T cell cellular chemokine Chemokine receptor Clinical sign CNS contributing to coronavirus Coronavirus infection Critical CX3CL1 CX3CR1 cytokine deficiency develop dissemination expression functions IFN IFNs immune protection Infection infiltration interferon-induced protein ISG ISGs lack leukocyte mechanism mice microglial Migration morbidity and mortality murine Neurological deficit neurotropic NK1.1 Pathogenesis PROTECT protective mechanism Protein receptor recruitment reduced regulate restrict significantly Spread stimulated Symptom T cell tissue homeostasis viral clearance Viral load viral replication virus virus load virus replication viruses wild-type [DOI] 10.1371/journal.ppat.1009034 PMC 바로가기 [Article Type] Research Article
Lung Ultrasound in Severe COVID-19 Pneumonia in the Sub-Intensive Care Unit: Beyond the Diagnostic PurposeCase report Published on 2020-11-272022-10-05 Journal: Respiratory Medicine Case Reports [Category] 진단, [키워드] arterial blood gase assist clinical evolution Clinical management Clinical sign conditions consolidation COVID-19 CPAP diagnostic employment lung failure Lung ultrasound management non-invasive ventilation Pneumonia severe COVID-19 disease Severe COVID-19 pneumonia the timing Ultrasound worsening [DOI] 10.1016/j.rmcr.2020.101307 [Article Type] Case report
Electroencephalographic Abnormalites in SARS-CoV-2 PatientsNeurology Published on 2020-11-262022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] abnormality agitated alteration Clinical sign Confusion Contact correlated COVID-19 COVID-19 patient de novo diagnosed diagnostic displaying Electroencephalography Encephalopathy epilepsy epileptic seizure exhibited eyelid favor indicated indications induce infection with SARS-CoV-2 investigated Loss of consciousness malaise Mild neurological Patient performed respiratory disorders Retrospective analysis SARS-CoV-2 Sedation Seizure Symptom the patient these symptoms virus [DOI] 10.3389/fneur.2020.582794 PMC 바로가기 [Article Type] Neurology
Lung ultrasound in outpatient approach to children with suspected COVID 19COVID 19 의심되는 어린이에 대한 외래 환자 접근의 폐 초음파Observational Study Published on 2020-11-232022-09-10 Journal: Italian Journal of Pediatrics [Category] SARS, 임상, 진단, 치료기술, [키워드] absence addition analysed approach children clinical examination Clinical sign Clinical signs cough COVID 19 detect diagnostic diagnostic test diagnostic tests disease distress Dyspnoea evaluate Evidence evidence of Fever Frequency highlight Hypoxemia Infection interstitial Italy lesion lung Lung injury lung involvement lung lesion lung lesions medical resource Mild Mild disease nasal swab observation pandemic performed persistent cough reliability reported respiratory distress Result Symptom test results [DOI] 10.1186/s13052-020-00938-w PMC 바로가기 [Article Type] Observational Study
COVID-19–Related Internet Search Patterns Among People in the United States: Exploratory AnalysisOriginal Paper Published on 2020-11-232022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, SARS, [키워드] accounted alcohol alleviate CDC center Clinical sign Control coronavirus COVID-19 COVID-19 outbreak database determine Google Government health information Health Organization identify infodemic infodemiology information information seeking infoveillance Internet majority media Modification natural language processing NLP objective organizations pandemic Patient pattern physician prevention provided question Result searched Symptom Symptoms the disease the United State The United States the WHO Topic Transmission Treatment turn virus website WHO World Health Organization [DOI] 10.2196/22407 PMC 바로가기 [Article Type] Original Paper
Current status on treatment options for feline infectious peritonitis and SARS-CoV-2 positive catsReview Published on 2020-11-132022-10-28 Journal: The Veterinary Quarterly [Category] COVID-19, MERS, SARS, [키워드] Antiviral antiviral drugs antiviral therapy approach cat caused Clinical effect Clinical sign coronavirus current feline Feline infectious peritonitis Feline infectious peritonitis virus FIP GS-441524 immune response immune system immune-mediated disease immunomodulator immunosuppressive agent increased survival information pandemic patients pharmacological positive Protease inhibitor provide reduce resulting robust SARS-CoV-2 stimulate Therapeutics treat Treatment viral-induced virulent virus [DOI] 10.1080/01652176.2020.1845917 PMC 바로가기 [Article Type] Review
The emerging role of neutrophil extracellular traps in severe acute respiratory syndrome coronavirus 2 (COVID-19)Article Published on 2020-11-122022-10-29 Journal: Scientific Reports [Category] COVID-19, [키워드] ACE2 activate acute respiratory distress acute respiratory syndrome angiotensin-converting enzyme 2 approach ARDS Asymptomatic cause Clinical sign common cold coronavirus COVID-19 death demonstrated disease Extracellular extrapulmonary tissues functional highly pathogenic Host human neutrophils indicated individual Infection investigated lymphocyte majority microthrombus multiorgan failure NETosis NETs neutrophil Neutrophil extracellular trap Neutrophils novel coronavirus SARS-CoV-2 pathway patients with comorbidity pro-inflammatory cytokine receptor ROS SARS-CoV-2 shown Specy stimulate symptomatic syndrome target cells the patient therapy thrombosis tissue upregulation viral infection Viral load virus entry [DOI] 10.1038/s41598-020-76781-0 PMC 바로가기 [Article Type] Article